Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
estradiol 0.5 MG / progesterone 100 MG Oral Capsule [Bijuva] estradiol	264	5.2%	T3	83.3%	1,289,816
Twice-Daily diclofenac epolamine 0.013 MG/MG Medicated Patch Twice-Daily diclofenac epolamine	264	5.2%	T3	81.7%	-
pilocarpine hydrochloride 12.5 MG/ML Ophthalmic Solution pilocarpine hydrochloride	262	5.2%	T2	13.6%	91,595
American house dust mite allergenic extract 6 SQ-HDM / European house dust mite allergenic extract 6 SQ-HDM Sublingual Tablet [Odactra] American house dust mite allergenic extract	262	5.2%	T3	83.3%	493
ciprofloxacin 100 MG/ML Oral Suspension [Cipro] ciprofloxacin	261	5.2%	T4	0%	1,810
zavegepant 10 MG Nasal Spray [Zavzpret] zavegepant	261	5.2%	T3	97.8%	999
60 ACTUAT fluticasone propionate 0.05 MG/ACTUAT Dry Powder Inhaler	261	5.2%	T2	0%	-
60 ACTUAT fluticasone propionate 0.1 MG/ACTUAT Dry Powder Inhaler	261	5.2%	T2	0%	-
60 ACTUAT fluticasone propionate 0.25 MG/ACTUAT Dry Powder Inhaler	261	5.2%	T2	0%	-
tretinoin 0.5 MG/ML Topical Lotion [Altreno] tretinoin	260	5.1%	T3	96.6%	91,688
prednisolone 10 MG Disintegrating Oral Tablet prednisolone	258	5.1%	T3	7.1%	20,337
brensocatib 10 MG Oral Tablet [Brinsupri] brensocatib	255	5%	T4	93.3%	-
brensocatib 25 MG Oral Tablet [Brinsupri] brensocatib	255	5%	T4	93.3%	-
acetaminophen 325 MG / butalbital 50 MG Oral Tablet acetaminophen	253	5%	T3	64.5%	156
esomeprazole 10 MG Granules for Oral Suspension esomeprazole	251	5%	T2	0%	685,529
esomeprazole 20 MG Granules for Oral Suspension esomeprazole	251	5%	T2	0%	685,529
esomeprazole 40 MG Granules for Oral Suspension esomeprazole	251	5%	T2	0%	685,529
lansoprazole 15 MG Disintegrating Oral Tablet lansoprazole	251	5%	T3	0%	303,222
lansoprazole 30 MG Disintegrating Oral Tablet lansoprazole	251	5%	T3	0%	303,222
hydrocortisone acetate 10 MG/ML / pramoxine hydrochloride 10 MG/ML Rectal Cream hydrocortisone acetate	251	5%	T3	0%	430
fluorometholone 2.5 MG/ML Ophthalmic Suspension [FML Forte Liquifilm] fluorometholone	250	4.9%	T3	0%	168,211
acetohydroxamic acid 250 MG Oral Tablet [Lithostat] acetohydroxamic acid	249	4.9%	T4	7.1%	203
seladelpar 10 MG Oral Capsule [Livdelzi] seladelpar	249	4.9%	T4	94.6%	-
clobetasol propionate 0.5 MG/ML Topical Spray clobetasol propionate	248	4.9%	T3	0%	1,250,981
{7 (lamotrigine 100 MG Disintegrating Oral Tablet) / 14 (lamotrigine 25 MG Disintegrating Oral Tablet) / 14 (lamotrigine 50 MG Disintegrating Oral Tablet) } Pack lamotrigine	248	4.9%	T2	0%	-
nilotinib 200 MG Oral Capsule [Tasigna] nilotinib	247	4.9%	T4	100%	2,961
nilotinib 150 MG Oral Capsule [Tasigna] nilotinib	247	4.9%	T4	100%	2,961
nilotinib 50 MG Oral Capsule [Tasigna] nilotinib	247	4.9%	T4	100%	2,961
{4 (amoxicillin 500 MG Oral Capsule) / 2 (clarithromycin 500 MG Oral Tablet) / 2 (lansoprazole 30 MG Delayed Release Oral Capsule) } Pack amoxicillin	245	4.8%	T2	0%	-
Abuse-Deterrent oxycodone hydrochloride 15 MG Oral Tablet Abuse-Deterrent oxycodone hydrochloride	244	4.8%	T2	0%	-
sotalol hydrochloride 5 MG/ML Oral Solution [Sotylize] sotalol hydrochloride	243	4.8%	T4	10%	262,533
prednisolone 30 MG Disintegrating Oral Tablet prednisolone	243	4.8%	T3	8.3%	20,337
abrocitinib 100 MG Oral Tablet [Cibinqo] abrocitinib	243	4.8%	T4	96.7%	347
chlordiazepoxide hydrochloride 5 MG / clidinium bromide 2.5 MG Oral Capsule chlordiazepoxide hydrochloride	242	4.8%	T2	33.3%	25,948
1 ML corticotropin 80 UNT/ML Prefilled Syringe [Cortrophin] corticotropin	241	4.8%	T4	100%	326
0.5 ML corticotropin 80 UNT/ML Prefilled Syringe [Cortrophin] corticotropin	241	4.8%	T4	100%	326
ticagrelor 90 MG Oral Tablet [Brilinta] ticagrelor	237	4.7%	T3	0%	234,770
iptacopan 200 MG Oral Capsule [Fabhalta] iptacopan	237	4.7%	T4	96.6%	-
rolapitant 90 MG Oral Tablet [Varubi] rolapitant	236	4.7%	T3	100%	187
budesonide 0.125 MG/ML Inhalation Suspension [Pulmicort] budesonide	235	4.6%	T4	100%	61,841
budesonide 0.25 MG/ML Inhalation Suspension [Pulmicort] budesonide	235	4.6%	T4	100%	61,841
budesonide 0.5 MG/ML Inhalation Suspension [Pulmicort] budesonide	235	4.6%	T4	100%	61,841
timolol hemihydrate 5 MG/ML Ophthalmic Solution timolol hemihydrate	235	4.6%	T1	0%	6,978
formoterol fumarate 0.01 MG/ML Inhalation Solution [Perforomist] formoterol fumarate	235	4.6%	T5	100%	3,044
amphotericin B liposomal 50 MG Injection [AmBisome] amphotericin B liposomal	234	4.6%	T4	81.8%	144
hydrocortisone acetate 10 MG/ML / pramoxine hydrochloride 10 MG/ML Rectal Foam [Proctofoam-HC] hydrocortisone acetate	231	4.6%	T2	0%	430
trofinetide 200 MG/ML Oral Solution [Daybue] trofinetide	231	4.6%	T4	94.7%	94
somatropin 8 MG/ML Injectable Solution [Serostim] somatropin	230	4.5%	T4	100%	1,572
somatropin 5 MG Injection [Serostim] somatropin	230	4.5%	T4	100%	1,572
somatropin 6 MG Injection [Serostim] somatropin	230	4.5%	T4	100%	1,572
0.6 ML pegfilgrastim-bmez 10 MG/ML Prefilled Syringe [Ziextenzo] pegfilgrastim-bmez	227	4.5%	T4	93.1%	809
betaine 1000 MG Powder for Oral Solution [Cystadane] betaine	227	4.5%	T4	0%	89
berdazimer 0.103 MG/MG Topical Gel [Zelsuvmi] berdazimer	227	4.5%	T4	90%	-
dalbavancin 500 MG Injection [Dalvance] dalbavancin	226	4.5%	T4	9.1%	1,299
fostamatinib 100 MG Oral Tablet [Tavalisse] fostamatinib	226	4.5%	T4	95.5%	486
fostamatinib 150 MG Oral Tablet [Tavalisse] fostamatinib	226	4.5%	T4	95.5%	486
solriamfetol 75 MG Oral Tablet [Sunosi] solriamfetol	225	4.4%	T3	96.3%	3,390
solriamfetol 150 MG Oral Tablet [Sunosi] solriamfetol	225	4.4%	T3	96.3%	3,390
{21 (dexamethasone 1.5 MG Oral Tablet) } Pack dexamethasone	224	4.4%	T3	0%	-
{35 (dexamethasone 1.5 MG Oral Tablet) } Pack dexamethasone	224	4.4%	T3	0%	-
{51 (dexamethasone 1.5 MG Oral Tablet) } Pack dexamethasone	224	4.4%	T3	0%	-
tiopronin 100 MG Delayed Release Oral Tablet tiopronin	222	4.4%	T4	63.3%	261
tiopronin 300 MG Delayed Release Oral Tablet tiopronin	222	4.4%	T4	63.3%	261
mefenamic acid 250 MG Oral Capsule mefenamic acid	221	4.4%	T3	0%	138
Abuse-Deterrent oxycodone hydrochloride 5 MG Oral Tablet Abuse-Deterrent oxycodone hydrochloride	221	4.4%	T4	0%	-
Abuse-Deterrent oxycodone hydrochloride 10 MG Oral Tablet Abuse-Deterrent oxycodone hydrochloride	221	4.4%	T4	0%	-
Abuse-Deterrent oxycodone hydrochloride 30 MG Oral Tablet Abuse-Deterrent oxycodone hydrochloride	221	4.4%	T4	0%	-
bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral Capsule bismuth subcitrate	220	4.3%	T3	0%	-
tiopronin 100 MG Oral Tablet tiopronin	218	4.3%	T4	39.4%	261
triamcinolone acetonide 0.0005 MG/MG Topical Ointment triamcinolone acetonide	217	4.3%	T3	0%	3,621,019
colchicine 0.6 MG Oral Capsule [Mitigare] colchicine	217	4.3%	T3	0%	553,640
dexamethasone 20 MG Oral Tablet [Hemady] dexamethasone	216	4.3%	T3	27.8%	850,184
ergotamine tartrate 2 MG Sublingual Tablet [Ergomar] ergotamine tartrate	215	4.2%	T4	0%	15
baricitinib 2 MG Oral Tablet [Olumiant] baricitinib	214	4.2%	T3	94.3%	1,389
baricitinib 1 MG Oral Tablet [Olumiant] baricitinib	214	4.2%	T3	94.3%	1,389
sildenafil 10 MG/ML Oral Suspension sildenafil	213	4.2%	T4	100%	253,277
azathioprine 75 MG Oral Tablet [Azasan] azathioprine	213	4.2%	T2	100%	90,745
azathioprine 100 MG Oral Tablet [Azasan] azathioprine	213	4.2%	T2	100%	90,745
givinostat 8.86 MG/ML Oral Suspension [Duvyzat] givinostat	212	4.2%	T4	92.3%	-
tesamorelin 2 MG Injection [Egrifta] tesamorelin	211	4.2%	T4	93.8%	653
tesamorelin 11.6 MG Injection [Egrifta] tesamorelin	211	4.2%	T4	93.5%	653
amifampridine 10 MG Oral Tablet [Firdapse] amifampridine	211	4.2%	T5	96.4%	356
anidulafungin 100 MG Injection [Eraxis] anidulafungin	211	4.2%	T4	45%	146
osilodrostat 1 MG Oral Tablet [Isturisa] osilodrostat	210	4.1%	T4	100%	202
osilodrostat 5 MG Oral Tablet [Isturisa] osilodrostat	210	4.1%	T4	100%	202
0.5 ML interferon beta-1a 0.088 MG/ML Prefilled Syringe [Rebif] interferon	209	4.1%	T4	72.3%	1,364
0.5 ML filgrastim-ayow 0.6 MG/ML Prefilled Syringe [Releuko] filgrastim-ayow	209	4.1%	T3	85.7%	-
0.8 ML filgrastim-ayow 0.6 MG/ML Prefilled Syringe [Releuko] filgrastim-ayow	209	4.1%	T3	85.7%	-
1 ML infliximab-dyyb 120 MG/ML Pen Injector [Zymfentra] infliximab-dyyb	209	4.1%	T4	88%	-
1 ML infliximab-dyyb 120 MG/ML Prefilled Syringe [Zymfentra] infliximab-dyyb	209	4.1%	T4	88%	-
1 ML nedosiran 160 MG/ML Prefilled Syringe [Rivfloza] nedosiran	207	4.1%	T4	100%	-
0.8 ML nedosiran 160 MG/ML Prefilled Syringe [Rivfloza] nedosiran	207	4.1%	T4	100%	-
0.5 ML nedosiran 160 MG/ML Injection [Rivfloza] nedosiran	207	4.1%	T4	100%	-
{4 (ozanimod 0.23 MG Oral Capsule [Zeposia]) / 3 (ozanimod 0.46 MG Oral Capsule [Zeposia]) } Pack [Zeposia 7-Day Starter Pack] ozanimod	206	4.1%	T4	93.3%	1,034
ozanimod 0.92 MG Oral Capsule [Zeposia] ozanimod	206	4.1%	T4	93.3%	1,034
tafenoquine 150 MG Oral Tablet [Krintafel] tafenoquine	206	4.1%	T4	0%	20
meprobamate 200 MG Oral Tablet meprobamate	204	4%	T2	45.5%	719
meprobamate 400 MG Oral Tablet meprobamate	204	4%	T2	45.5%	719
levacetylleucine 1000 MG Granules for Oral Suspension [Aqneursa] levacetylleucine	203	4%	T4	93.5%	-
Preservative-Free timolol 2.5 MG/ML Ophthalmic Solution Preservative-Free timolol	202	4%	T3	8.3%	-

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team