Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
erythromycin ethylsuccinate 80 MG/ML Oral Suspension erythromycin ethylsuccinate	353	7%	T3	0%	1,861
nemolizumab-ilto 30 MG Auto-Injector [Nemluvio] nemolizumab-ilto	351	6.9%	T4	98.3%	-
tolcapone 100 MG Oral Tablet tolcapone	348	6.9%	T4	17.4%	25
corticotropin 80 UNT/ML Injectable Solution [Cortrophin] corticotropin	347	6.8%	T4	100%	942
2 ML lanadelumab-flyo 150 MG/ML Injection [Takhzyro] lanadelumab-flyo	341	6.7%	T5	93.5%	27
2 ML lanadelumab-flyo 150 MG/ML Prefilled Syringe [Takhzyro] lanadelumab-flyo	341	6.7%	T5	93.5%	27
0.5 ML ustekinumab-ttwe 90 MG/ML Prefilled Syringe ustekinumab-ttwe	341	6.7%	T3	87.5%	-
1 ML ustekinumab-ttwe 90 MG/ML Prefilled Syringe ustekinumab-ttwe	341	6.7%	T5	87.5%	-
insulin aspart-szjj 100 UNT/ML Injectable Solution [Merilog] insulin aspart-szjj	339	6.7%	T3	12.5%	418,431
3 ML insulin aspart-szjj 100 UNT/ML Pen Injector [Merilog] insulin aspart-szjj	339	6.7%	T3	0%	-
200 ACTUAT albuterol 0.09 MG/ACTUAT Dry Powder Inhaler [ProAir]	338	6.7%	T3	0%	-
sacubitril 24 MG / valsartan 26 MG Oral Tablet [Entresto] sacubitril	337	6.7%	T3	0%	663,587
sacubitril 97 MG / valsartan 103 MG Oral Tablet [Entresto] sacubitril	337	6.7%	T3	0%	663,587
sacubitril 49 MG / valsartan 51 MG Oral Tablet [Entresto] sacubitril	337	6.7%	T3	0%	663,587
elagolix 150 MG Oral Tablet [Orilissa] elagolix	334	6.6%	T4	95.9%	66
elagolix 200 MG Oral Tablet [Orilissa] elagolix	334	6.6%	T4	95.9%	66
buprenorphine 0.075 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.15 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.3 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.45 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.6 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.75 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
buprenorphine 0.9 MG Buccal Film [Belbuca] buprenorphine	332	6.6%	T3	82.5%	74,893
{28 (alpelisib 50 MG Oral Granules [Vijoice]) } Pack [Vijoice 50 MG Granules 28 Day] alpelisib	331	6.5%	T4	93%	31
1 ML certolizumab pegol 200 MG/ML Prefilled Syringe [Cimzia] certolizumab pegol	330	6.5%	T4	100%	5,602
amitriptyline hydrochloride 12.5 MG / chlordiazepoxide 5 MG Oral Tablet amitriptyline hydrochloride	329	6.5%	T2	25.9%	838,449
amitriptyline hydrochloride 25 MG / chlordiazepoxide 10 MG Oral Tablet amitriptyline hydrochloride	329	6.5%	T2	25.9%	838,449
certolizumab pegol 200 MG Injection [Cimzia] certolizumab pegol	325	6.4%	T4	100%	5,602
{6 (1 ML certolizumab pegol 200 MG/ML Prefilled Syringe [Cimzia]) } Pack [Cimzia Starter Kit (6 count)] certolizumab pegol	325	6.4%	T4	100%	5,602
{6 (0.2 ML interferon beta-1a 0.044 MG/ML Prefilled Syringe [Rebif]) / 6 (0.5 ML interferon beta-1a 0.044 MG/ML Prefilled Syringe [Rebif]) } Pack [Rebif Titration] interferon	324	6.4%	T4	71.4%	1,364
1 ML lanadelumab-flyo 150 MG/ML Prefilled Syringe [Takhzyro] lanadelumab-flyo	322	6.4%	T5	92.9%	27
30 ACTUAT umeclidinium 0.0625 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler	321	6.3%	T3	0%	-
adapalene 0.001 MG/MG / benzoyl peroxide 0.025 MG/MG Topical Gel adapalene	320	6.3%	T2	8.7%	4,155
{6 (0.2 ML interferon beta-1a 0.044 MG/ML Auto-Injector [Rebif]) / 6 (0.5 ML interferon beta-1a 0.044 MG/ML Auto-Injector [Rebif]) } Pack [Rebif Rebidose] interferon	320	6.3%	T4	70.8%	1,364
0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] interferon	320	6.3%	T4	70.8%	1,364
metronidazole 125 MG Oral Tablet metronidazole	316	6.2%	T2	0%	1,528,785
12 HR oxymorphone hydrochloride 5 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
12 HR oxymorphone hydrochloride 7.5 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
12 HR oxymorphone hydrochloride 10 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
12 HR oxymorphone hydrochloride 15 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
12 HR oxymorphone hydrochloride 20 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
12 HR oxymorphone hydrochloride 30 MG Extended Release Oral Tablet oxymorphone hydrochloride	316	6.2%	T3	0%	-
risdiplam 5 MG Oral Tablet [Evrysdi] risdiplam	313	6.2%	T4	98.4%	424
0.5 ML interferon beta-1a 0.044 MG/ML Auto-Injector [Rebif] interferon	312	6.2%	T4	72.3%	1,364
deferiprone 100 MG/ML Oral Solution [Ferriprox] deferiprone	312	6.2%	T5	77.8%	198
0.15 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	311	6.1%	T3	4.8%	5,262
0.2 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	311	6.1%	T3	4.8%	5,262
0.25 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	311	6.1%	T3	4.8%	5,262
0.45 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	311	6.1%	T3	4.8%	5,262
0.6 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	311	6.1%	T3	4.8%	5,262
{24 (ethinyl estradiol 0.02 MG / norethindrone acetate 1 MG Oral Capsule) / 4 (ferrous fumarate 75 MG Oral Capsule) } Pack ethinyl estradiol	311	6.1%	T2	0%	-
opicapone 25 MG Oral Capsule [Ongentys] opicapone	310	6.1%	T3	25.8%	3,270
opicapone 50 MG Oral Capsule [Ongentys] opicapone	310	6.1%	T3	25.8%	3,270
14 ACTUAT budesonide 2 MG/ACTUAT Rectal Foam	309	6.1%	T2	8.2%	-
prednisolone 5 MG Oral Tablet prednisolone	307	6.1%	T3	28.6%	20,337
{28 (alpelisib 50 MG Oral Tablet [Vijoice]) } Pack [Vijoice 50 MG 28 Day] alpelisib	307	6.1%	T4	92.3%	31
{28 (alpelisib 125 MG Oral Tablet [Vijoice]) } Pack [Vijoice 125 MG 28 Day] alpelisib	307	6.1%	T4	92.3%	31
12 HR oxymorphone hydrochloride 40 MG Extended Release Oral Tablet oxymorphone hydrochloride	304	6%	T3	0%	-
macitentan 10 MG / tadalafil 20 MG Oral Tablet [Opsynvi] macitentan	303	6%	T4	100%	9,031
macitentan 10 MG / tadalafil 40 MG Oral Tablet [Opsynvi] macitentan	303	6%	T4	100%	9,031
lofexidine 0.18 MG Oral Tablet lofexidine	303	6%	T4	46.2%	781
0.3 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	302	6%	T3	3.2%	5,262
0.35 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	302	6%	T3	3.2%	5,262
0.4 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	302	6%	T3	3.2%	5,262
0.5 ML methotrexate 50 MG/ML Auto-Injector [Rasuvo] methotrexate	302	6%	T3	3.2%	5,262
prednisolone 15 MG Disintegrating Oral Tablet prednisolone	292	5.8%	T3	6.7%	20,337
arimoclomol 124 MG Oral Capsule [Miplyffa] arimoclomol	291	5.7%	T4	98.4%	-
arimoclomol 47 MG Oral Capsule [Miplyffa] arimoclomol	291	5.7%	T4	98.4%	-
arimoclomol 62 MG Oral Capsule [Miplyffa] arimoclomol	291	5.7%	T4	98.4%	-
arimoclomol 93 MG Oral Capsule [Miplyffa] arimoclomol	291	5.7%	T4	98.4%	-
maralixibat 10 MG Oral Tablet [Livmarli] maralixibat	286	5.6%	T4	95.3%	-
maralixibat 15 MG Oral Tablet [Livmarli] maralixibat	286	5.6%	T4	95.3%	-
maralixibat 20 MG Oral Tablet [Livmarli] maralixibat	286	5.6%	T4	95.3%	-
maralixibat 30 MG Oral Tablet [Livmarli] maralixibat	286	5.6%	T4	95.3%	-
{21 (ethinyl estradiol 0.02 MG / levonorgestrel 0.1 MG Oral Tablet) / 7 (ferrous bisglycinate 36.5 MG Oral Tablet) } Pack [Minzoya 28 Day] ethinyl estradiol	286	5.6%	T2	0%	-
0.8 ML olezarsen 100 MG/ML Auto-Injector [Tryngolza] olezarsen	286	5.6%	T4	94.1%	-
olsalazine sodium 250 MG Oral Capsule [Dipentum] olsalazine sodium	285	5.6%	T4	0%	215
acetaminophen 325 MG / butalbital 50 MG / caffeine 40 MG / codeine phosphate 30 MG Oral Capsule acetaminophen	283	5.6%	T2	61.3%	156
{24 (ethinyl estradiol 0.02 MG / norethindrone acetate 1 MG Oral Capsule) / 4 (ferrous fumarate 75 MG Oral Capsule) } Pack [Merzee 28 Day] ethinyl estradiol	283	5.6%	T2	0%	-
suzetrigine 50 MG Oral Tablet [Journavx] suzetrigine	281	5.5%	T3	25.5%	-
alprazolam 0.25 MG Disintegrating Oral Tablet alprazolam	280	5.5%	T2	5%	2,265,351
alprazolam 0.5 MG Disintegrating Oral Tablet alprazolam	280	5.5%	T2	5%	2,265,351
alprazolam 1 MG Disintegrating Oral Tablet alprazolam	280	5.5%	T2	5%	2,265,351
alprazolam 2 MG Disintegrating Oral Tablet alprazolam	280	5.5%	T2	5%	2,265,351
60 ACTUAT budesonide 0.09 MG/ACTUAT Dry Powder Inhaler [Pulmicort]	279	5.5%	T3	0%	394
120 ACTUAT budesonide 0.18 MG/ACTUAT Dry Powder Inhaler [Pulmicort]	279	5.5%	T3	0%	394
90 DAY estradiol 0.00208 MG/HR Vaginal System [Femring]	278	5.5%	T3	0%	2,894
90 DAY estradiol 0.00417 MG/HR Vaginal System [Femring]	278	5.5%	T3	0%	2,894
ivermectin 10 MG/ML Topical Cream ivermectin	276	5.4%	T3	40.5%	40,953
ritlecitinib 50 MG Oral Capsule [Litfulo] ritlecitinib	276	5.4%	T4	97.9%	26
trientine tetrahydrochloride 300 MG Oral Tablet [Cuvrior] trientine tetrahydrochloride	276	5.4%	T4	100%	-
ketoprofen 50 MG Oral Capsule ketoprofen	272	5.4%	T3	0%	1,019
0.8 ML filgrastim 0.6 MG/ML Prefilled Syringe [Neupogen] filgrastim	269	5.3%	T5	71.4%	1,092
1 ML filgrastim 0.3 MG/ML Injection [Neupogen] filgrastim	269	5.3%	T5	71.4%	1,092
1.6 ML filgrastim 0.3 MG/ML Injection [Neupogen] filgrastim	269	5.3%	T5	71.4%	1,092
0.5 ML filgrastim 0.6 MG/ML Prefilled Syringe [Neupogen] filgrastim	269	5.3%	T5	71.4%	1,092
nitrofurantoin 5 MG/ML Oral Suspension nitrofurantoin	267	5.3%	T3	8%	1,444
paroxetine mesylate 7.5 MG Oral Capsule paroxetine mesylate	267	5.3%	T3	7.1%	1,010
{21 (ethinyl estradiol 0.02 MG / levonorgestrel 0.1 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Joyeaux 28 Day] ethinyl estradiol	265	5.2%	T3	0%	-
estradiol 1 MG / progesterone 100 MG Oral Capsule [Bijuva] estradiol	264	5.2%	T3	83.3%	1,289,816

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team