Medicare Part D coverage · 0.5 · RxCUI 1650004
0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif]
Per the CMS 2026 Part D formulary file, 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] is covered by 307 Medicare Part D plans (6.1% of enrollable products), averaging Tier 4.3, with prior authorization required on 70.2% of covering formularies.
- 6.1%
- Plan coverage
- 307
- Plans covering
- T4.3
- Avg tier
- 70.2%
- Prior auth required
What the CMS Formulary Data Shows for 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif]
Per the CMS 2026 Part D formulary file, 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] (RxNorm concept RXCUI 1650004, generic name 0.5) appears on 47 distinct formulary files spanning 307 Medicare Part D plan offerings - 6.1% of enrollable Part D products, selective placement; verify formulary inclusion before enrolling. Tier placement ranges from Tier 1 to Tier 5, with a cross-plan average of Tier 4.3.
Real-world access to 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] depends on utilization management as much as tier placement: 70.2% of covering formularies require prior authorization. 8.5% require step therapy. 48.9% apply quantity limits.
Historical spending context from the CMS Medicare Part D Drug Spending Dashboard shows 1,364 Part D beneficiaries filled 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] in 2023, with total plan-and-beneficiary spending of $131,300,521 and an average per-beneficiary annual cost of $96,261.38. The plan-by-plan detail below lists exactly which PDP and MA-PD contracts carry 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] today.
Coverage Details
- Formularies covering
- 47
- Plans covering
- 307
- Coverage rate
- 6.1%
- Tier range
- Tier 1 – Tier 5
- Average tier
- Tier 4, Non-Preferred
Restrictions
- Prior authorization required
- 70.2% of formularies
- Step therapy required
- 8.5% of formularies
- Quantity limits
- 48.9% of formularies
2023 Medicare Spending
- Beneficiaries
- 1,364
- Total spending
- $131,300,521
- Avg per beneficiary
- $96,261.38
Tier Distribution Across Plans
Medicare Advantage Plans (MA-PD) Covering 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif]
100 Medicare Advantage plans with Part D drug coverage include this drug.
| Plan | Insurer | Tier | PA | Premium | States |
|---|---|---|---|---|---|
| SeniorCare Complete (HMO D-SNP) | South Country Health Alliance | T1 | Yes | $0 | MN |
| AbilityCare (HMO D-SNP) | South Country Health Alliance | T1 | Yes | $0 | MN |
| Alameda Alliance Wellness (HMO D-SNP) | Alameda Alliance FOR Health | T1 | Yes | $0 | CA |
| Provider Partners Pennsylvania Community Plan (HMO I-SNP) | Provider Partners Health Plan OF Pennsylvania, Inc | T1 | Yes | $0 | PA |
| Provider Partners North Carolina Community Plan (HMO I-SNP) | Provider Partners Health Plan OF North Carolina | T1 | Yes | $0 | NC |
| Provider Partners Indiana Community Plan (HMO I-SNP) | Provider Partners Health Plan OF Indiana | T1 | Yes | $0 | IN |
| Provider Partners Missouri Community Plan (HMO I-SNP) | Provider Partners Health Plan OF Missouri, Inc. | T1 | Yes | $0 | MO |
| Community Care's Partnership Program (HMO D-SNP) | Community Care Health Plan, Inc. | T1 | No | $0 | WI |
| Mass General Brigham SCO (HMO D-SNP) | Mass General Brigham Health Plan, Inc | T1 | No | $0 | MA |
| Mass General Brigham One Care (HMO D-SNP) | Mass General Brigham Health Plan, Inc | T1 | No | $0 | MA |
| Tufts Health One Care (HMO D-SNP) | Tufts Health Public Plans, Inc. | T1 | No | $0 | MA |
| Tufts Health One Care CW (HMO D-SNP) | Tufts Health Public Plans, Inc. | T1 | No | $0 | MA |
| Tufts Health Plan Senior Care Options (HMO D-SNP) | Tufts Associated Health Maintenance Organization | T1 | No | $0 | MA |
| Tufts Health Plan Senior Care Options CW (HMO D-SNP) | Tufts Associated Health Maintenance Organization | T1 | No | $0 | MA |
| Provider Partners Texas Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Texas, Inc. | T1 | Yes | $4.80 | TX |
| Provider Partners Illinois Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Illinois | T1 | Yes | $15.20 | IL |
| Provider Partners Pennsylvania Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Pennsylvania, Inc | T1 | Yes | $32.70 | PA |
| Provider Partners Pennsylvania Essential Plan (HMO I-SNP) | Provider Partners Health Plan OF Pennsylvania, Inc | T1 | Yes | $32.70 | PA |
| Provider Partners North Carolina Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF North Carolina | T1 | Yes | $36.20 | NC |
| Provider Partners North Carolina Essential Plan (HMO I-SNP) | Provider Partners Health Plan OF North Carolina | T1 | Yes | $36.20 | NC |
Show the next 30 plans
| Provider Partners Indiana Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Indiana | T1 | Yes | $38.40 | IN |
| Provider Partners Indiana Essential Plan (HMO I-SNP) | Provider Partners Health Plan OF Indiana | T1 | Yes | $38.40 | IN |
| Provider Partners Kentucky Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Kentucky | T1 | Yes | $38.40 | KY |
| Provider Partners Missouri Advantage Plan (HMO I-SNP) | Provider Partners Health Plan OF Missouri, Inc. | T1 | Yes | $43.00 | MO |
| Provider Partners Missouri Essential Plan (HMO I-SNP) | Provider Partners Health Plan OF Missouri, Inc. | T1 | Yes | $43.00 | MO |
| CalOptima Health OneCare Complete (HMO D-SNP) | Orange County Health Authority | T2 | Yes | $0 | CA |
| Medicare BlueEssential (PPO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Medicare BlueActive (PPO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Medicare BlueVital (PPO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Univera SeniorChoice Basic (HMO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Univera SeniorChoice Extra (HMO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Medicare Blue Choice Core (HMO) | Excellus Health Plan, Inc. | T5 | No | $0 | NY |
| Univera Medicare Dual (HMO D-SNP) | Excellus Health Plan Community Care LLC | T5 | No | $0 | NY |
| Medicare Blue Dual (HMO D-SNP) | Excellus Health Plan Community Care LLC | T5 | No | $0 | NY |
| Personal Choice 65 Achieve Rx (PPO) | QCC Insurance Company | T5 | No | $0 | PA |
| Keystone 65 Focus Rx (HMO-POS) | Keystone Health Plan East, Inc. | T5 | No | $0 | PA |
| Keystone 65 Focus Rx (HMO-POS) | Keystone Health Plan East, Inc. | T5 | No | $0 | PA |
| Keystone 65 Basic Rx (HMO) | Keystone Health Plan East, Inc. | T5 | No | $0 | PA |
| AmeriHealth Medicare Core (PPO) | Amerihealth Insurance Company OF NEW Jersey | T5 | No | $0 | NJ |
| AmeriHealth Medicare Ultimate (PPO) | Amerihealth Insurance Company OF NEW Jersey | T5 | No | $0 | NJ |
| eternalHealth Forever (HMO) | Eternalhealth, Inc. | T5 | Yes | $0 | MA |
| eternalHealth Freedom (PPO) | Eternalhealth, Inc. | T5 | Yes | $0 | MA |
| eternalHealth Give Back (PPO) | Eternalhealth, Inc. | T5 | Yes | $0 | MA |
| eternalHealth Horizon (HMO) | Eternalhealth OF Arizona Inc | T5 | Yes | $0 | AZ |
| eternalHealth Grand Give Back (HMO) | Eternalhealth OF Arizona Inc | T5 | Yes | $0 | AZ |
| eternalHealth + Fry's Medicare Advantage (HMO) | Eternalhealth OF Arizona Inc | T5 | Yes | $0 | AZ |
| Senior Care Plus Essential plan (HMO) | Hometown Health Plan, Inc. | T5 | Yes | $0 | NV |
| Senior Care Plus Complete Plan (HMO) | Hometown Health Plan, Inc. | T5 | Yes | $0 | NV |
| Renown Preferred Plan by Senior Care Plus (HMO) | Hometown Health Plan, Inc. | T5 | Yes | $0 | NV |
| Senior Care Plus Extensive Duals Plan (HMO D-SNP) | Hometown Health Plan, Inc. | T5 | Yes | $0 | NV |
Showing top 50 of 100 plans.
Frequently Asked Questions
Is 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] covered by Medicare Part D?
Yes, 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] is covered by 307 Medicare Part D plans (6.1% of all Part D formularies).
What tier is 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] on Medicare Part D plans?
0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] averages Tier 4.3 across Part D plans, ranging from Tier 1 to Tier 5.
Does 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] require prior authorization?
70.2% of Part D formularies require prior authorization for 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif]. Step therapy: 8.5%. Quantity limits: 48.9%.
How much does Medicare spend on 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif]?
In 2023, total Medicare Part D spending on 0.5 ML interferon beta-1a 0.088 MG/ML Auto-Injector [Rebif] was $131,300,521, covering 1,364 beneficiaries. The average spend per beneficiary was $96,261.38.
Read our methodology - how this data is sourced, computed, and verified.
Nationwide similar Part D drugs
Data-derived peers across the CMS Part D formulary extract: nearest average tier placement and nearest prior-authorization rate. Not therapeutic alternatives or same-generic strengths.
Closest average formulary tier
- nitisinone 2 MG Oral Capsule T4.3
- Pediatric 1.5 ML leuprolide acetate 7.5 MG/ML Prefilled Syringe [Lupron] T4.3
- nafarelin 0.2 MG/ACTUAT Metered Dose Nasal Spray [Synarel] T4.3
- 10 ML immunoglobulin G, human 100 MG/ML Injection [Gammaked] T4.3
- C1 esterase inhibitor (human) 500 UNT Injection [Berinert] T4.3
- 0.6 ML risperidone 150 MG/ML Prefilled Syringe [Perseris] T4.3
Similar prior-authorization rate
- {6 (0.2 ML interferon beta-1a 0.044 MG/ML Auto-Injector [Rebif]) / 6 (0.5 ML interferon beta-1a 0.044 MG/ML Auto-Injector [Rebif]) } Pack [Rebif Rebidose] 70.2% PA
- diclofenac sodium 0.03 MG/MG Topical Gel 70.3% PA
- lactulose 10000 MG Powder for Oral Solution [Kristalose] 70% PA
- Twice-Daily deferiprone 1000 MG Oral Tablet [Ferriprox] 70% PA
- megestrol acetate 125 MG/ML Oral Suspension 69.9% PA
- aripiprazole 2 MG Oral Film [Opipza] 69.8% PA