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Medicare Part D drugs starting with R

82 drugs start with R; 40 of them are on at least 90% of 2026 Part D formularies. Part D spending was highest for Revlimid in 2024: $4.2 billion, what plans and patients paid at the pharmacy before rebates.

Which drugs start with R?

By name; spending is what plans and patients paid at the pharmacy in 2024 (“no 2024 match”: no row of the CMS spending file can be tied to this product alone)
DrugPlans coveringUsual tierMedicare spending, 2024
RabAvert (rabies vaccine)100%Tier 1$1 million
Rabeprazole sodium73.7%Tier 2$13 million
Radicava (edaravone)31.4%Tier 5$5 million
Raldesy (trazodone hydrochloride)100%Tier 4no 2024 match
Raloxifene hydrochloride100%Tier 2$32 million
Ramelteon71%Tier 4$24 million
Ramipril100%Tier 1$17 million
Ranitidine0.5%Tier 1no 2024 match
Ranolazine100%Tier 4$111 million
Rasagiline100%Tier 4$28 million
Rasuvo (methotrexate)6.2%Tier 4$22 million
Rayaldee (calcifediol)29.3%Tier 5$43 million
Rebif (interferon beta-1a)6.2%Tier 5$105 million
Reclipsen (desogestrel / ethinyl estradiol)96.6%Tier 2$7 thousand
Recombivax (hepatitis B vaccine)100%Tier 1no 2024 match
Recorlev (levoketoconazole)2.6%Tier 5$30 million
Rectiv (nitroglycerin)1%Tier 4$2 million
Redemplo (plozasiran)1.2%Tier 5no 2024 match
Reglan (metoclopramide)under 0.1%Tier 1$68 thousand
Relenza (zanamivir)87.1%Tier 4$13 thousand
Releuko (filgrastim-ayow)4.1%Tier 4$92 thousand
Relexxii (methylphenidate hydrochloride)0.1%Tier 3$39 thousand
Relistor (methylnaltrexone bromide)25.4%Tier 5$135 million
Remeron (mirtazapine)under 0.1%Tier 1$732 thousand
Repaglinide100%Tier 1$12 million
Repatha (evolocumab)92.8%Tier 3$1.9 billion
Restasis (cyclosporine)59.7%Tier 3$1.3 billion
Retacrit (epoetin alfa-epbx)54.3%Tier 4$27 million
Retevmo (selpercatinib)100%Tier 5$85 million
Retin-A (tretinoin)2.3%Tier 2$1 million
Retrovir (zidovudine)0.2%Tier 1no 2024 match
Revcovi (elapegademase-lvlr)100%Tier 5$40 million
Revlimid (lenalidomide)3.5%Tier 5$4.2 billion
Revuforj (revumenib)100%Tier 5$1 million
Rextovy (naloxone hydrochloride)44.8%Tier 4no 2024 match
Rexulti (brexpiprazole)100%Tier 5$861 million
Reyataz (atazanavir)100%Tier 5$650 thousand
Rezdiffra (resmetirom)100%Tier 5$69 million
Rezlidhia (olutasidenib)100%Tier 5$15 million
Rezurock (belumosudil)52.5%Tier 5$243 million
Show the other 42 drugs
DrugPlans coveringUsual tierMedicare spending, 2024
Rezvoglar (insulin glargine-aglr)1.1%Tier 2$586 thousand
Rhapsido (remibrutinib)0.3%Tier 5no 2024 match
Rhopressa (netarsudil)91.4%Tier 3$168 million
Ribavirin100%Tier 3$246 thousand
Ridaura (auranofin)15.2%Tier 3$922 thousand
Rifabutin100%Tier 4$7 million
Rifampin100%Tier 3$7 million
Riluzole100%Tier 4$8 million
Rimantadine hydrochloride89.1%Tier 4$126 thousand
Rinvoq (upadacitinib)98.2%Tier 5$1.4 billion
Risedronate sodium88.6%Tier 3$26 million
Risperdal (risperidone)26.5%Tier 4$4 million
Risperidone100%Tier 2$97 million
Ritalin (methylphenidate hydrochloride)0.2%Tier 1$1 million
Ritonavir100%Tier 3$6 million
Rivaroxaban89.4%Tier 3no 2024 match
Rivastigmine100%Tier 2$89 million
Rivelsa (ethinyl estradiol)30.3%Tier 2$4 thousand
Rivfloza (nedosiran)3.8%Tier 5no 2024 match
Rizatriptan98.8%Tier 2$15 million
Rocaltrol (calcitriol)under 0.1%Tier 1$17 thousand
Rocklatan (latanoprost / netarsudil)89.5%Tier 3$167 million
Roflumilast100%Tier 4$32 million
Romvimza (vimseltinib)100%Tier 5no 2024 match
Ropinirole100%Tier 2$65 million
Rosuvastatin calcium100%Tier 1$437 million
Rosyrah (ethinyl estradiol)41.5%Tier 2no 2024 match
Rotarix (rotavirus vaccine)100%Tier 1no 2024 match
RotaTeq (rotavirus vaccine)100%Tier 1no 2024 match
Rowasa (mesalamine)0.3%Tier 4$44 thousand
Roweepra (levetiracetam)93.9%Tier 2$749
Roxicodone (oxycodone hydrochloride)under 0.1%Tier 1$2 million
Rozerem (ramelteon)under 0.1%Tier 1$735 thousand
Rozlytrek (entrectinib)100%Tier 5$19 million
Rubraca (rucaparib)100%Tier 5$32 million
Ruconest (C1 esterase inhibitor, recombinant)0.1%Tier 6$56 million
Rufinamide100%Tier 4$30 million
Rukobia (fostemsavir)100%Tier 5$115 million
Ryaltris (mometasone furoate / olopatadine hydrochloride)20.3%Tier 4$3 million
Rybelsus (semaglutide)93.8%Tier 3$1.9 billion
Rydapt (midostaurin)100%Tier 5$27 million
Rytary (carbidopa / levodopa)12%Tier 4$272 million

Source: CMS Part D formulary file, 2026 second quarter; CMS Medicare Part D Spending by Drug, 2024.

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