Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
cyclosporine, modified 25 MG Oral Capsule [Neoral] cyclosporine, modified	120	2.4%	T3	100%	492,479
cyclosporine, modified 100 MG Oral Capsule [Neoral] cyclosporine, modified	120	2.4%	T3	100%	492,479
1 ML satralizumab-mwge 120 MG/ML Prefilled Syringe [Enspryng] satralizumab-mwge	120	2.4%	T4	100%	220
sebetralstat 300 MG Oral Tablet [Ekterly] sebetralstat	120	2.4%	T4	60%	-
buspirone hydrochloride 15 MG Oral Capsule [Bucapsol] buspirone hydrochloride	119	2.3%	T5	0%	1,420,432
doxycycline hyclate 200 MG Delayed Release Oral Tablet doxycycline hyclate	118	2.3%	T2	0%	4,121,486
estradiol 0.1 MG/ML Vaginal Cream [Estrace] estradiol	118	2.3%	T2	0%	1,289,816
tretinoin 0.25 MG/ML Topical Cream [Retin-A] tretinoin	117	2.3%	T2	66.7%	91,688
tretinoin 0.5 MG/ML Topical Cream [Retin-A] tretinoin	117	2.3%	T2	66.7%	91,688
tretinoin 1 MG/ML Topical Cream [Retin-A] tretinoin	117	2.3%	T2	66.7%	91,688
tretinoin 0.00025 MG/MG Topical Gel [Retin-A] tretinoin	117	2.3%	T2	66.7%	91,688
tretinoin 0.0001 MG/MG Topical Gel [Retin-A] tretinoin	117	2.3%	T2	66.7%	91,688
glycopyrrolate 1.5 MG Oral Tablet glycopyrrolate	117	2.3%	T2	0%	51,524
1.14 ML sarilumab 132 MG/ML Auto-Injector [Kevzara] sarilumab	117	2.3%	T4	100%	4,167
efavirenz 600 MG / lamivudine 300 MG / tenofovir disoproxil fumarate 300 MG Oral Tablet [Symfi] efavirenz	117	2.3%	T4	0%	1,779
12 HR carbamazepine 100 MG Extended Release Oral Capsule [Carbatrol] carbamazepine	117	2.3%	T2	0%	1,707
12 HR carbamazepine 200 MG Extended Release Oral Capsule [Carbatrol] carbamazepine	117	2.3%	T2	0%	1,707
12 HR carbamazepine 300 MG Extended Release Oral Capsule [Carbatrol] carbamazepine	117	2.3%	T2	0%	1,707
0.574 ML zilucoplan 40 MG/ML Prefilled Syringe [Zilbrysq] zilucoplan	116	2.3%	T4	100%	-
0.81 ML zilucoplan 40 MG/ML Prefilled Syringe [Zilbrysq] zilucoplan	116	2.3%	T4	100%	-
hydrocortisone 1 MG/ML Oral Solution [Khindivi] hydrocortisone	115	2.3%	T5	0%	1,257,661
indomethacin 50 MG Rectal Suppository [Indocin] indomethacin	115	2.3%	T5	0%	123,532
halobetasol propionate 0.5 MG/ML Topical Foam halobetasol propionate	115	2.3%	T4	0%	89,868
168 HR estradiol 0.00208 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
168 HR estradiol 0.00417 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
168 HR estradiol 0.00312 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
168 HR estradiol 0.00104 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
168 HR estradiol 0.00156 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
168 HR estradiol 0.0025 MG/HR Transdermal System [Climara] estradiol	115	2.3%	T2	0%	6,601
diflunisal 375 MG Oral Tablet [Dolobid] diflunisal	115	2.3%	T5	0%	3,325
flurandrenolide 0.004 MG/SQCM Medicated Tape [Cordran] flurandrenolide	115	2.3%	T4	0%	1,839
tasimelteon 4 MG/ML Oral Suspension [Hetlioz] tasimelteon	115	2.3%	T4	100%	499
tiopronin 100 MG Oral Tablet [Thiola] tiopronin	115	2.3%	T5	0%	261
sarecycline 100 MG Oral Tablet [Seysara] sarecycline	115	2.3%	T5	0%	190
birch triterpenes 0.1 MG/MG Topical Gel [Filsuvez] birch triterpenes	115	2.3%	T4	100%	-
24 HR minocycline 40 MG Extended Release Oral Capsule [Emrosi] minocycline	115	2.3%	T5	0%	-
berotralstat 150 MG Oral Capsule [Orladeyo] berotralstat	113	2.2%	T5	100%	158
berotralstat 110 MG Oral Capsule [Orladeyo] berotralstat	113	2.2%	T5	100%	158
palovarotene 1 MG Oral Capsule [Sohonos] palovarotene	113	2.2%	T4	100%	-
palovarotene 1.5 MG Oral Capsule [Sohonos] palovarotene	113	2.2%	T4	100%	-
palovarotene 2.5 MG Oral Capsule [Sohonos] palovarotene	113	2.2%	T4	100%	-
palovarotene 5 MG Oral Capsule [Sohonos] palovarotene	113	2.2%	T4	100%	-
palovarotene 10 MG Oral Capsule [Sohonos] palovarotene	113	2.2%	T4	100%	-
24 HR amantadine 68.5 MG Extended Release Oral Capsule [Gocovri] amantadine	112	2.2%	T4	88.2%	4,464
24 HR amantadine 137 MG Extended Release Oral Capsule [Gocovri] amantadine	112	2.2%	T4	88.2%	4,464
{2 (1.17 ML romosozumab-aqqg 89.7 MG/ML Prefilled Syringe [Evenity]) } Pack [Evenity 210 MG Dose] romosozumab-aqqg	112	2.2%	T4	100%	145
60 ACTUAT exenatide 0.005 MG/ACTUAT Pen Injector	112	2.2%	T3	100%	-
60 ACTUAT exenatide 0.01 MG/ACTUAT Pen Injector	112	2.2%	T3	100%	-
{18 (oteseconazole 150 MG Oral Capsule [Vivjoa]) } Pack [Vivjoa 18-Count] oteseconazole	109	2.2%	T4	100%	71
lusutrombopag 3 MG Oral Tablet [Mulpleta] lusutrombopag	109	2.2%	T5	100%	28
fluticasone propionate 0.5 MG/ML Topical Lotion fluticasone propionate	108	2.1%	T2	0%	4,902,813
1.14 ML sarilumab 132 MG/ML Prefilled Syringe [Kevzara] sarilumab	108	2.1%	T4	100%	4,167
1.14 ML sarilumab 175 MG/ML Prefilled Syringe [Kevzara] sarilumab	108	2.1%	T4	100%	4,167
1.14 ML sarilumab 175 MG/ML Auto-Injector [Kevzara] sarilumab	108	2.1%	T4	100%	4,167
sirolimus 0.002 MG/MG Topical Gel [Hyftor] sirolimus	107	2.1%	T5	100%	7,218
12 HR hydrocodone bitartrate 10 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
12 HR hydrocodone bitartrate 15 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
12 HR hydrocodone bitartrate 20 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
12 HR hydrocodone bitartrate 30 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
12 HR hydrocodone bitartrate 40 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
12 HR hydrocodone bitartrate 50 MG Extended Release Oral Capsule hydrocodone bitartrate	107	2.1%	T4	28.6%	-
riluzole 5 MG/ML Oral Suspension [Tiglutik] riluzole	106	2.1%	T3	42.1%	9,582
benzoyl peroxide 0.025 MG/MG / clindamycin phosphate 0.012 MG/MG Topical Gel benzoyl peroxide	106	2.1%	T2	0%	465
metreleptin 5 MG/ML Injectable Solution [Myalept] metreleptin	106	2.1%	T5	100%	13
0.416 ML zilucoplan 40 MG/ML Prefilled Syringe [Zilbrysq] zilucoplan	106	2.1%	T4	100%	-
doxycycline hyclate 50 MG Delayed Release Oral Tablet doxycycline hyclate	105	2.1%	T2	0%	4,121,486
doxycycline hyclate 100 MG Delayed Release Oral Tablet doxycycline hyclate	105	2.1%	T3	0%	4,121,486
betamethasone 0.0005 MG/MG / calcipotriene 0.00005 MG/MG Topical Ointment betamethasone	105	2.1%	T4	21.4%	407,711
mesna 400 MG Oral Tablet [Mesnex] mesna	105	2.1%	T5	0%	284
200 ACTUAT levalbuterol 0.045 MG/ACTUAT Metered Dose Inhaler [Xopenex]	105	2.1%	T3	0%	-
cyclosporine 25 MG Oral Capsule [Sandimmune] cyclosporine	104	2.1%	T3	100%	492,479
cyclosporine 100 MG Oral Capsule [Sandimmune] cyclosporine	104	2.1%	T4	100%	492,479
tacrolimus 0.5 MG Oral Capsule [Prograf] tacrolimus	104	2.1%	T3	100%	204,385
tacrolimus 1 MG Oral Capsule [Prograf] tacrolimus	104	2.1%	T3	100%	204,385
tacrolimus 5 MG Oral Capsule [Prograf] tacrolimus	104	2.1%	T4	100%	204,385
apraclonidine 10 MG/ML Ophthalmic Solution [Iopidine] apraclonidine	104	2.1%	T4	0%	1,543
mycophenolic acid 180 MG Delayed Release Oral Tablet [Myfortic] mycophenolic acid	104	2.1%	T3	100%	215
0.5 ML ustekinumab-hmny 90 MG/ML Prefilled Syringe [Starjemza] ustekinumab-hmny	104	2.1%	T3	100%	-
0.5 ML ustekinumab-hmny 90 MG/ML Injection [Starjemza] ustekinumab-hmny	104	2.1%	T3	100%	-
tobramycin 60 MG/ML Inhalation Solution [Kitabis] tobramycin	103	2%	T4	100%	195,319
naloxone 0.5 MG / pentazocine 50 MG Oral Tablet naloxone	102	2%	T2	5.9%	744,446
mycophenolic acid 360 MG Delayed Release Oral Tablet [Myfortic] mycophenolic acid	102	2%	T4	100%	215
almotriptan 6.25 MG Oral Tablet almotriptan	100	2%	T3	0%	1,289
almotriptan 12.5 MG Oral Tablet almotriptan	100	2%	T3	0%	1,289
cyclosporine, modified 100 MG/ML Oral Solution [Neoral] cyclosporine, modified	99	2%	T3	100%	492,479
budesonide 0.2 MG/ML Oral Suspension [Eohilia] budesonide	99	2%	T4	100%	61,841
mycophenolate mofetil 250 MG Oral Capsule [Cellcept] mycophenolate mofetil	98	1.9%	T4	100%	105,503
mycophenolate mofetil 500 MG Oral Tablet [Cellcept] mycophenolate mofetil	98	1.9%	T4	100%	105,503
baricitinib 4 MG Oral Tablet [Olumiant] baricitinib	98	1.9%	T3	100%	1,389
24 HR oxcarbazepine 150 MG Extended Release Oral Tablet oxcarbazepine	98	1.9%	T3	0%	-
24 HR oxcarbazepine 300 MG Extended Release Oral Tablet oxcarbazepine	98	1.9%	T3	0%	-
24 HR oxcarbazepine 600 MG Extended Release Oral Tablet oxcarbazepine	98	1.9%	T4	0%	-
digoxin 0.25 MG Oral Tablet [Lanoxin] digoxin	97	1.9%	T3	0%	392,747
liothyronine sodium 0.005 MG Oral Tablet [Cytomel] liothyronine sodium	97	1.9%	T3	0%	171,270
liothyronine sodium 0.025 MG Oral Tablet [Cytomel] liothyronine sodium	97	1.9%	T3	0%	171,270
liothyronine sodium 0.05 MG Oral Tablet [Cytomel] liothyronine sodium	97	1.9%	T3	0%	171,270
Modified 24 HR metformin hydrochloride 1000 MG Extended Release Oral Tablet Modified	97	1.9%	T3	25%	-
1 ML ustekinumab-hmny 90 MG/ML Prefilled Syringe [Starjemza] ustekinumab-hmny	96	1.9%	T3	100%	-
bosentan 32 MG Tablet for Oral Suspension [Tracleer] bosentan	95	1.9%	T4	100%	715
prednisolone 10 MG Disintegrating Oral Tablet [Orapred] prednisolone	94	1.9%	T3	25%	20,337

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team