Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
Sprinkle 24 HR topiramate 200 MG Extended Release Oral Capsule Sprinkle	719	14.2%	T3	5.6%	-
Sprinkle 24 HR topiramate 25 MG Extended Release Oral Capsule Sprinkle	719	14.2%	T3	5.6%	-
Sprinkle 24 HR topiramate 100 MG Extended Release Oral Capsule Sprinkle	719	14.2%	T3	5.6%	-
Modified 24 HR metformin hydrochloride 500 MG Extended Release Oral Tablet Modified	717	14.2%	T4	66.7%	-
zolmitriptan 2.5 MG Disintegrating Oral Tablet zolmitriptan	715	14.1%	T2	0%	11,158
desloratadine 2.5 MG Disintegrating Oral Tablet desloratadine	711	14%	T3	0%	42,939
1.7 ML denosumab-bnht 70 MG/ML Prefilled Syringe [Bomyntra] denosumab-bnht	707	14%	T4	98.4%	-
isosorbide dinitrate 40 MG Oral Tablet isosorbide dinitrate	706	13.9%	T3	0%	129,460
3 ML liraglutide 6 MG/ML Pen Injector liraglutide	705	13.9%	T2	99%	-
3 ML somatropin 10 MG/ML Pen Injector [Norditropin] somatropin	703	13.9%	T4	100%	-
canagliflozin 50 MG / metformin hydrochloride 500 MG Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	69,576
canagliflozin 50 MG / metformin hydrochloride 1000 MG Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	69,576
canagliflozin 150 MG / metformin hydrochloride 500 MG Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	69,576
canagliflozin 150 MG / metformin hydrochloride 1000 MG Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	69,576
desloratadine 5 MG Disintegrating Oral Tablet desloratadine	699	13.8%	T3	0%	42,939
24 HR canagliflozin 50 MG / metformin hydrochloride 500 MG Extended Release Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	4,565
24 HR canagliflozin 50 MG / metformin hydrochloride 1000 MG Extended Release Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	4,565
24 HR canagliflozin 150 MG / metformin hydrochloride 500 MG Extended Release Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	4,565
24 HR canagliflozin 150 MG / metformin hydrochloride 1000 MG Extended Release Oral Tablet [Invokamet] canagliflozin	699	13.8%	T4	0%	4,565
canagliflozin 100 MG Oral Tablet [Invokana] canagliflozin	695	13.7%	T3	0%	69,576
canagliflozin 300 MG Oral Tablet [Invokana] canagliflozin	695	13.7%	T3	0%	69,576
24 HR pregabalin 82.5 MG Extended Release Oral Tablet pregabalin	694	13.7%	T3	43.8%	-
24 HR pregabalin 165 MG Extended Release Oral Tablet pregabalin	694	13.7%	T3	43.8%	-
24 HR pregabalin 330 MG Extended Release Oral Tablet pregabalin	694	13.7%	T3	43.8%	-
theophylline 300 MG Extended Release Oral Capsule [Theo-24] theophylline	693	13.7%	T3	0%	39,063
1.7 ML denosumab-bnht 70 MG/ML Injection [Bomyntra] denosumab-bnht	692	13.7%	T4	98.3%	-
lactulose 20000 MG Powder for Oral Solution lactulose	690	13.6%	T3	50%	526,962
clindamycin 10 MG/ML Topical Foam clindamycin	690	13.6%	T3	0%	8,722
deflazacort 6 MG Oral Tablet [Kymbee] deflazacort	688	13.6%	T4	100%	99
deflazacort 18 MG Oral Tablet [Kymbee] deflazacort	688	13.6%	T4	100%	99
deflazacort 30 MG Oral Tablet [Kymbee] deflazacort	688	13.6%	T4	100%	99
deflazacort 36 MG Oral Tablet [Kymbee] deflazacort	688	13.6%	T4	100%	99
gepotidacin 750 MG Oral Tablet [Blujepa] gepotidacin	687	13.6%	T3	1.8%	-
24 HR methylphenidate hydrochloride 72 MG Extended Release Oral Tablet methylphenidate hydrochloride	684	13.5%	T2	3.3%	-
ketoconazole 20 MG/ML Topical Foam [Ketodan] ketoconazole	680	13.4%	T4	0%	1,750,875
dapsone 0.05 MG/MG Topical Gel dapsone	674	13.3%	T4	0%	25,257
lactulose 20000 MG Powder for Oral Solution [Kristalose] lactulose	671	13.2%	T4	63.6%	526,962
hydrocortisone butyrate 1 MG/ML Topical Solution hydrocortisone butyrate	670	13.2%	T2	0%	6,139
lactulose 10000 MG Powder for Oral Solution [Kristalose] lactulose	667	13.2%	T4	70%	526,962
deferiprone 1000 MG Oral Tablet deferiprone	667	13.2%	T4	90%	198
deferiprone 500 MG Oral Tablet deferiprone	667	13.2%	T4	90%	198
bromocriptine 0.8 MG Oral Tablet [Cycloset] bromocriptine	666	13.1%	T4	2.6%	6,713
metronidazole 0.0075 MG/MG Vaginal Gel [Vandazole] metronidazole	661	13%	T3	0%	1,528,785
metoclopramide 5 MG Disintegrating Oral Tablet metoclopramide	660	13%	T2	0%	402,098
phenoxybenzamine hydrochloride 10 MG Oral Capsule phenoxybenzamine hydrochloride	655	12.9%	T5	26.7%	157
clindamycin 10 MG/ML Topical Foam [Clindacin] clindamycin	653	12.9%	T4	0%	8,722
fenoprofen 400 MG Oral Capsule fenoprofen	645	12.7%	T4	0%	270
12 HR carbinoxamine maleate 0.8 MG/ML Extended Release Suspension carbinoxamine maleate	645	12.7%	T4	100%	-
imiquimod 25 MG/ML Topical Cream [Zyclara] imiquimod	640	12.6%	T5	0%	124,101
insulin lispro 100 UNT/ML Injectable Solution [Admelog] insulin lispro	639	12.6%	T3	93%	418,431
3 ML insulin lispro 100 UNT/ML Pen Injector [Admelog] insulin lispro	639	12.6%	T3	1.8%	4,971
metronidazole 10 MG/ML Topical Cream [Noritate] metronidazole	636	12.6%	T5	0%	1,528,785
200 ML vancomycin 5 MG/ML Injection [Tyzavan] vancomycin	636	12.6%	T2	0%	-
carisoprodol 350 MG Oral Tablet carisoprodol	632	12.5%	T2	58.3%	62,766
8 HR carbidopa 23.75 MG / levodopa 95 MG Extended Release Oral Capsule [Rytary] carbidopa	625	12.3%	T4	1.7%	32,157
8 HR carbidopa 36.25 MG / levodopa 145 MG Extended Release Oral Capsule [Rytary] carbidopa	625	12.3%	T4	1.7%	32,157
8 HR carbidopa 48.75 MG / levodopa 195 MG Extended Release Oral Capsule [Rytary] carbidopa	625	12.3%	T4	1.7%	32,157
8 HR carbidopa 61.25 MG / levodopa 245 MG Extended Release Oral Capsule [Rytary] carbidopa	625	12.3%	T4	1.7%	32,157
24 HR methylphenidate hydrochloride 63 MG Extended Release Oral Tablet methylphenidate hydrochloride	621	12.3%	T4	0%	-
24 HR methylphenidate hydrochloride 45 MG Extended Release Oral Tablet methylphenidate hydrochloride	621	12.3%	T4	0%	-
120 ACTUAT fluticasone propionate 0.22 MG/ACTUAT Metered Dose Inhaler	617	12.2%	T3	0%	-
naftifine hydrochloride 10 MG/ML Topical Cream naftifine hydrochloride	613	12.1%	T3	0%	8,135
1 ML tbo-filgrastim 0.3 MG/ML Injection [Granix] tbo-filgrastim	612	12.1%	T5	93.3%	430
60 ACTUAT fluticasone propionate 0.055 MG/ACTUAT / salmeterol 0.014 MG/ACTUAT Dry Powder Inhaler	611	12.1%	T2	0%	-
60 ACTUAT fluticasone propionate 0.113 MG/ACTUAT / salmeterol 0.014 MG/ACTUAT Dry Powder Inhaler	611	12.1%	T2	0%	-
60 ACTUAT fluticasone propionate 0.232 MG/ACTUAT / salmeterol 0.014 MG/ACTUAT Dry Powder Inhaler	611	12.1%	T2	0%	-
pyridostigmine bromide 12 MG/ML Oral Solution pyridostigmine bromide	610	12%	T3	0%	56,300
vancomycin 50 MG/ML Oral Solution vancomycin	608	12%	T3	0%	161,077
Sensor 3 ML insulin lispro 100 UNT/ML Pen Injector [Humalog] Sensor	607	12%	T3	1.4%	156,031
ascorbic acid 4700 MG / polyethylene glycol 3350 100000 MG / potassium chloride 1015 MG / sodium ascorbate 5900 MG / sodium chloride 2690 MG / sodium sulfate 7500 MG Powder for Oral Solution ascorbic acid	597	11.8%	T2	0%	-
loteprednol etabonate 10 MG/ML Ophthalmic Suspension [Inveltys] loteprednol etabonate	595	11.7%	T2	0%	91,483
azathioprine 100 MG Oral Tablet azathioprine	594	11.7%	T2	100%	90,745
azathioprine 75 MG Oral Tablet azathioprine	590	11.6%	T2	100%	90,745
theophylline 100 MG Extended Release Oral Capsule [Theo-24] theophylline	590	11.6%	T4	0%	39,063
naftifine hydrochloride 20 MG/ML Topical Cream naftifine hydrochloride	588	11.6%	T3	0%	8,135
C1 esterase inhibitor (human) 500 UNT Injection [Cinryze] C1	587	11.6%	T4	97.6%	191
0.5 ML peginterferon beta-1a 0.25 MG/ML Auto-Injector [Plegridy] peginterferon	586	11.6%	T4	77.7%	-
0.5 ML peginterferon beta-1a 0.25 MG/ML Prefilled Syringe [Plegridy] peginterferon	586	11.6%	T4	77.7%	-
120 ACTUAT fluticasone propionate 0.044 MG/ACTUAT Metered Dose Inhaler	583	11.5%	T3	0%	-
120 ACTUAT fluticasone propionate 0.11 MG/ACTUAT Metered Dose Inhaler	583	11.5%	T3	0%	-
theophylline 200 MG Extended Release Oral Capsule [Theo-24] theophylline	578	11.4%	T4	0%	39,063
theophylline 400 MG Extended Release Oral Capsule [Theo-24] theophylline	578	11.4%	T4	0%	39,063
nifedipine 10 MG Oral Capsule nifedipine	574	11.3%	T2	23.3%	849,024
nifedipine 20 MG Oral Capsule nifedipine	574	11.3%	T2	23.3%	849,024
0.5 ML tbo-filgrastim 0.6 MG/ML Prefilled Syringe [Granix] tbo-filgrastim	573	11.3%	T5	93%	430
0.8 ML tbo-filgrastim 0.6 MG/ML Prefilled Syringe [Granix] tbo-filgrastim	573	11.3%	T5	93%	430
24 HR pramipexole dihydrochloride 4.5 MG Extended Release Oral Tablet pramipexole dihydrochloride	564	11.1%	T3	0%	-
24 HR pramipexole dihydrochloride 3.75 MG Extended Release Oral Tablet pramipexole dihydrochloride	564	11.1%	T3	0%	-
1 ML alirocumab 75 MG/ML Auto-Injector [Praluent] alirocumab	563	11.1%	T3	100%	-
1 ML alirocumab 150 MG/ML Auto-Injector [Praluent] alirocumab	563	11.1%	T3	100%	-
naftifine hydrochloride 0.02 MG/MG Topical Gel naftifine hydrochloride	549	10.8%	T3	0%	8,135
saxagliptin 2.5 MG Oral Tablet saxagliptin	540	10.7%	T2	0%	5,089
saxagliptin 5 MG Oral Tablet saxagliptin	540	10.7%	T2	0%	5,089
mavacamten 2.5 MG Oral Capsule [Camzyos] mavacamten	527	10.4%	T4	100%	2,006
mavacamten 5 MG Oral Capsule [Camzyos] mavacamten	527	10.4%	T4	100%	2,006
mavacamten 10 MG Oral Capsule [Camzyos] mavacamten	527	10.4%	T4	100%	2,006
mavacamten 15 MG Oral Capsule [Camzyos] mavacamten	527	10.4%	T4	100%	2,006
vancomycin 25 MG/ML Oral Solution vancomycin	526	10.4%	T3	0%	161,077
penciclovir 10 MG/ML Topical Cream penciclovir	525	10.4%	T3	3.2%	3,267
eluxadoline 75 MG Oral Tablet [Viberzi] eluxadoline	519	10.2%	T4	55.9%	7,023

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team