Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
0.5 ML ustekinumab-stba 90 MG/ML Prefilled Syringe [Steqeyma] ustekinumab-stba	1,725	34%	T3	100%	-
escitalopram 15 MG Oral Capsule escitalopram	1,722	34%	T4	29%	2,538,742
1.7 ML denosumab-bmwo 70 MG/ML Injection [Osenvelt] denosumab-bmwo	1,719	33.9%	T4	84.8%	-
bromfenac 0.7 MG/ML Ophthalmic Solution bromfenac	1,717	33.9%	T3	0%	144,112
24 HR rotigotine 0.0417 MG/HR Transdermal System [Neupro] rotigotine	1,711	33.8%	T3	2.9%	15,325
24 HR trospium chloride 60 MG Extended Release Oral Capsule trospium chloride	1,706	33.7%	T3	2.1%	-
3 ML insulin degludec 100 UNT/ML / liraglutide 3.6 MG/ML Pen Injector [Xultophy] insulin degludec	1,703	33.6%	T3	0%	-
24 HR rotigotine 0.0833 MG/HR Transdermal System [Neupro] rotigotine	1,702	33.6%	T3	2.9%	15,325
24 HR rotigotine 0.125 MG/HR Transdermal System [Neupro] rotigotine	1,702	33.6%	T3	2.9%	15,325
24 HR rotigotine 0.167 MG/HR Transdermal System [Neupro] rotigotine	1,702	33.6%	T3	2.9%	15,325
24 HR rotigotine 0.25 MG/HR Transdermal System [Neupro] rotigotine	1,702	33.6%	T3	2.9%	15,325
24 HR rotigotine 0.333 MG/HR Transdermal System [Neupro] rotigotine	1,702	33.6%	T3	2.9%	15,325
promethazine hydrochloride 25 MG Rectal Suppository [Promethegan] promethazine hydrochloride	1,701	33.6%	T3	47.3%	523,738
{1 (ascorbic acid 7540 MG / polyethylene glycol 3350 40000 MG / potassium chloride 1200 MG / sodium ascorbate 48110 MG / sodium chloride 3200 MG Powder for Oral Solution) / 1 (polyethylene glycol 3350 100000 MG / potassium chloride 1000 MG / sodium chloride 2000 MG / sodium sulfate 9000 MG Powder for Oral Solution) } Pack [Plenvu] ascorbic acid	1,696	33.5%	T3	0%	56,685
1 ML denosumab-bbdz 60 MG/ML Prefilled Syringe [Jubbonti] denosumab-bbdz	1,695	33.5%	T3	37.4%	-
0.5 ML ustekinumab-ttwe 90 MG/ML Injection [Pyzchiva] ustekinumab-ttwe	1,691	33.4%	T3	100%	-
cefadroxil 1000 MG Oral Tablet cefadroxil	1,690	33.4%	T2	0%	315,336
duloxetine 40 MG Delayed Release Oral Capsule duloxetine	1,688	33.3%	T2	0%	2,465,211
0.5 ML ustekinumab-ttwe 90 MG/ML Prefilled Syringe [Pyzchiva] ustekinumab-ttwe	1,684	33.2%	T3	100%	-
1 ML ustekinumab-ttwe 90 MG/ML Prefilled Syringe [Pyzchiva] ustekinumab-ttwe	1,684	33.2%	T4	100%	-
cephalexin 750 MG Oral Capsule cephalexin	1,682	33.2%	T3	0%	5,051,787
{5 (milnacipran hydrochloride 12.5 MG Oral Tablet [Savella]) / 8 (milnacipran hydrochloride 25 MG Oral Tablet [Savella]) / 42 (milnacipran hydrochloride 50 MG Oral Tablet [Savella]) } Pack [Savella 4-Week Titration] milnacipran hydrochloride	1,673	33%	T3	11.8%	16,373
milnacipran hydrochloride 100 MG Oral Tablet [Savella] milnacipran hydrochloride	1,673	33%	T3	11.8%	16,373
milnacipran hydrochloride 12.5 MG Oral Tablet [Savella] milnacipran hydrochloride	1,673	33%	T3	11.8%	16,373
milnacipran hydrochloride 25 MG Oral Tablet [Savella] milnacipran hydrochloride	1,673	33%	T3	11.8%	16,373
milnacipran hydrochloride 50 MG Oral Tablet [Savella] milnacipran hydrochloride	1,673	33%	T3	11.8%	16,373
fluticasone propionate 0.093 MG/ACTUAT Metered Dose Nasal Spray [Xhance] fluticasone propionate	1,669	32.9%	T3	66.3%	4,902,813
miglustat 100 MG Oral Capsule miglustat	1,656	32.7%	T4	95%	22
0.25 ML paliperidone palmitate 156 MG/ML Prefilled Syringe [Erzofri] paliperidone palmitate	1,650	32.6%	T4	14.2%	-
amitriptyline hydrochloride 10 MG / perphenazine 2 MG Oral Tablet amitriptyline hydrochloride	1,648	32.5%	T2	23.4%	838,449
pitavastatin calcium 1 MG Oral Tablet pitavastatin calcium	1,640	32.4%	T2	0%	70,926
pitavastatin calcium 2 MG Oral Tablet pitavastatin calcium	1,640	32.4%	T2	0%	70,926
pitavastatin calcium 4 MG Oral Tablet pitavastatin calcium	1,640	32.4%	T2	0%	70,926
amitriptyline hydrochloride 10 MG / perphenazine 4 MG Oral Tablet amitriptyline hydrochloride	1,633	32.2%	T2	23.8%	838,449
icosapent ethyl 1000 MG Oral Capsule icosapent ethyl	1,626	32.1%	T3	0.5%	279,946
60 ACTUAT ciclesonide 0.08 MG/ACTUAT Metered Dose Inhaler [Alvesco]	1,619	32%	T3	0%	88,457
60 ACTUAT ciclesonide 0.16 MG/ACTUAT Metered Dose Inhaler [Alvesco]	1,619	32%	T3	0%	88,457
icosapent ethyl 500 MG Oral Capsule icosapent ethyl	1,618	31.9%	T3	0.5%	279,946
patiromer 1000 MG Powder for Oral Suspension [Veltassa] patiromer	1,615	31.9%	T3	20.4%	43,162
amitriptyline hydrochloride 25 MG / perphenazine 2 MG Oral Tablet amitriptyline hydrochloride	1,613	31.8%	T2	22.6%	838,449
amitriptyline hydrochloride 25 MG / perphenazine 4 MG Oral Tablet amitriptyline hydrochloride	1,613	31.8%	T2	22.6%	838,449
ciprofloxacin 2 MG/ML / hydrocortisone 10 MG/ML Otic Suspension [Cipro HC] ciprofloxacin	1,613	31.8%	T4	0%	1,810
mepolizumab 100 MG Injection [Nucala] mepolizumab	1,612	31.8%	T4	100%	7,618
12 HR clonidine hydrochloride 0.1 MG Extended Release Oral Tablet clonidine hydrochloride	1,612	31.8%	T2	4.3%	-
1 ML denosumab-bmwo 60 MG/ML Prefilled Syringe [Stoboclo] denosumab-bmwo	1,604	31.7%	T3	36.6%	-
loteprednol etabonate 2 MG/ML Ophthalmic Suspension loteprednol etabonate	1,603	31.6%	T2	0.9%	91,483
60 ACTUAT olodaterol 0.0025 MG/ACTUAT Inhalation Spray [Striverdi]	1,602	31.6%	T3	0%	-
alpha 1-proteinase inhibitor, human 1 MG Injection [Zemaira] alpha	1,600	31.6%	T4	100%	226
amitriptyline hydrochloride 50 MG / perphenazine 4 MG Oral Tablet amitriptyline hydrochloride	1,598	31.5%	T2	23.1%	838,449
methylphenidate hydrochloride 2.5 MG Chewable Tablet methylphenidate hydrochloride	1,597	31.5%	T3	31.6%	108,959
insulin lispro-aabc 100 UNT/ML Injectable Solution [Lyumjev] insulin lispro-aabc	1,597	31.5%	T3	24.8%	13,588
3 ML insulin lispro-aabc 100 UNT/ML Pen Injector [Lyumjev] insulin lispro-aabc	1,597	31.5%	T3	0.8%	3,723
3 ML insulin lispro-aabc 200 UNT/ML Pen Injector [Lyumjev] insulin lispro-aabc	1,597	31.5%	T3	0.8%	3,723
bromfenac 0.75 MG/ML Ophthalmic Solution bromfenac	1,596	31.5%	T3	0%	144,112
1 ML hydromorphone hydrochloride 10 MG/ML Injection hydromorphone hydrochloride	1,595	31.5%	T3	29.3%	-
sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] sapropterin dihydrochloride	1,594	31.5%	T4	98.8%	137
sapropterin dihydrochloride 100 MG Powder for Oral Solution [Javygtor] sapropterin dihydrochloride	1,591	31.4%	T4	98.8%	137
edaravone 21 MG/ML Oral Suspension [Radicava] edaravone	1,587	31.3%	T4	99%	2,994
benzoyl peroxide 0.05 MG/MG / clindamycin phosphate 0.012 MG/MG Topical Gel [Neuac] benzoyl peroxide	1,586	31.3%	T2	0%	465
fluorometholone acetate 1 MG/ML Ophthalmic Suspension [Flarex] fluorometholone acetate	1,583	31.2%	T3	0%	15,372
eltrombopag 9 MG Oral Tablet [Alvaiz] eltrombopag	1,575	31.1%	T4	99.2%	5,708
eltrombopag 18 MG Oral Tablet [Alvaiz] eltrombopag	1,575	31.1%	T4	99.2%	5,708
eltrombopag 36 MG Oral Tablet [Alvaiz] eltrombopag	1,575	31.1%	T4	99.2%	5,708
eltrombopag 54 MG Oral Tablet [Alvaiz] eltrombopag	1,575	31.1%	T4	99.2%	5,708
{126 (12 HR treprostinil 0.125 MG Extended Release Oral Tablet [Orenitram]) / 42 (12 HR treprostinil 0.25 MG Extended Release Oral Tablet [Orenitram]) } Pack [Orenitram Month 1 Titration Kit] treprostinil	1,559	30.8%	T5	100%	-
{126 (12 HR treprostinil 0.125 MG Extended Release Oral Tablet [Orenitram]) / 210 (12 HR treprostinil 0.25 MG Extended Release Oral Tablet [Orenitram]) } Pack [Orenitram Month 2 Titration Kit] treprostinil	1,559	30.8%	T5	100%	-
{126 (12 HR treprostinil 0.125 MG Extended Release Oral Tablet [Orenitram]) / 42 (12 HR treprostinil 0.25 MG Extended Release Oral Tablet [Orenitram]) / 84 (12 HR treprostinil 1 MG Extended Release Oral Tablet [Orenitram]) } Pack [Orenitram Month 3 Titration Kit] treprostinil	1,559	30.8%	T5	100%	-
tedizolid phosphate 200 MG Oral Tablet [Sivextro] tedizolid phosphate	1,554	30.7%	T5	69.4%	489
clobetasol propionate 0.5 MG/ML Topical Foam clobetasol propionate	1,552	30.6%	T3	0%	1,250,981
fenofibrate 50 MG Oral Capsule fenofibrate	1,552	30.6%	T2	0%	500,170
clindamycin 10 MG/ML Medicated Pad [Clindacin] clindamycin	1,550	30.6%	T3	0%	8,722
sacrosidase 8500 UNT/ML Oral Solution [Sucraid] sacrosidase	1,550	30.6%	T4	80.2%	1,656
{7 (ethinyl estradiol 0.01 MG Oral Tablet) / 42 (ethinyl estradiol 0.02 MG / levonorgestrel 0.15 MG Oral Tablet) / 21 (ethinyl estradiol 0.025 MG / levonorgestrel 0.15 MG Oral Tablet) / 21 (ethinyl estradiol 0.03 MG / levonorgestrel 0.15 MG Oral Tablet) } Pack [Rivelsa 91 Day] ethinyl estradiol	1,546	30.5%	T2	0%	-
3 ML insulin lispro 100 UNT/ML Pen Injector insulin lispro	1,544	30.5%	T3	0%	-
0.6 ML pegfilgrastim-jmdb 10 MG/ML Prefilled Syringe [Fulphila] pegfilgrastim-jmdb	1,537	30.3%	T4	78.9%	173
Breath-Actuated 120 ACTUAT beclomethasone dipropionate 0.04 MG/ACTUAT Metered Dose Inhaler [Qvar] Breath-Actuated	1,536	30.3%	T3	0%	-
Breath-Actuated 120 ACTUAT beclomethasone dipropionate 0.08 MG/ACTUAT Metered Dose Inhaler [Qvar] Breath-Actuated	1,536	30.3%	T3	0%	-
plecanatide 3 MG Oral Tablet [Trulance] plecanatide	1,529	30.2%	T3	0.8%	41,836
3 ML apomorphine hydrochloride 10 MG/ML Cartridge apomorphine hydrochloride	1,521	30%	T5	88%	-
24 HR methylphenidate hydrochloride 54 MG Extended Release Oral Tablet methylphenidate hydrochloride	1,512	29.8%	T2	2.8%	-
24 HR methylphenidate hydrochloride 18 MG Extended Release Oral Tablet methylphenidate hydrochloride	1,512	29.8%	T2	2.8%	-
24 HR methylphenidate hydrochloride 27 MG Extended Release Oral Tablet methylphenidate hydrochloride	1,512	29.8%	T2	2.8%	-
24 HR methylphenidate hydrochloride 36 MG Extended Release Oral Tablet methylphenidate hydrochloride	1,508	29.8%	T2	2.9%	-
naproxen 25 MG/ML Oral Suspension naproxen	1,507	29.7%	T3	8.6%	1,344,536
24 HR calcifediol 0.03 MG Extended Release Oral Capsule [Rayaldee] calcifediol	1,493	29.5%	T4	1%	4,889
ciprofloxacin 0.003 MG/MG Ophthalmic Ointment [Ciloxan] ciprofloxacin	1,488	29.4%	T3	1.3%	1,810
miglustat 100 MG Oral Capsule [Yargesa] miglustat	1,484	29.3%	T4	97.7%	22
methylphenidate hydrochloride 5 MG Chewable Tablet methylphenidate hydrochloride	1,482	29.2%	T3	32.3%	108,959
methylphenidate hydrochloride 10 MG Chewable Tablet methylphenidate hydrochloride	1,482	29.2%	T3	32.3%	108,959
hydroxychloroquine sulfate 100 MG Oral Tablet hydroxychloroquine sulfate	1,478	29.2%	T2	0%	583,911
{56 (mitapivat 5 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 5 MG 4-Week] mitapivat	1,471	29%	T5	98.1%	26
{56 (mitapivat 20 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 20 MG 4-Week] mitapivat	1,471	29%	T5	98.1%	26
{56 (mitapivat 50 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 50 MG 4-Week] mitapivat	1,471	29%	T5	98.1%	26
{7 (mitapivat 5 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 5 MG Taper] mitapivat	1,471	29%	T5	98.1%	26
{7 (mitapivat 20 MG Oral Tablet [Pyrukynd]) / 7 (mitapivat 5 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 5 MG / 20 MG Taper] mitapivat	1,471	29%	T5	98.1%	26
{7 (mitapivat 20 MG Oral Tablet [Pyrukynd]) / 7 (mitapivat 50 MG Oral Tablet [Pyrukynd]) } Pack [Pyrukynd 20 MG / 50 MG Taper] mitapivat	1,471	29%	T5	98.1%	26
indomethacin 75 MG Extended Release Oral Capsule indomethacin	1,458	28.8%	T2	0%	123,532
24 HR venlafaxine 112.5 MG Extended Release Oral Tablet venlafaxine	1,458	28.8%	T3	1.2%	-
C1 esterase inhibitor (human) 500 UNT Injection [Berinert] C1	1,453	28.7%	T4	97.4%	191
0.5 UNT Doses 3 ML insulin lispro 100 UNT/ML Pen Injector Doses	1,447	28.6%	T2	0%	-

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team