Medicare Part D coverage · sapropterin dihydrochloride · RxCUI 2621237

sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]

Per the CMS 2026 Part D formulary file, sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] is covered by 1,593 Medicare Part D plans (31.5% of enrollable products), averaging Tier 4.3, with prior authorization required on 98.8% of covering formularies.

31.5%
Plan coverage
1,593
Plans covering
T4.3
Avg tier
98.8%
Prior auth required

Verify with CMS →

Important: Drug coverage and costs vary by plan and location. Verify coverage directly with your Medicare plan before filling a prescription. This is informational data only and should not replace advice from your healthcare provider or pharmacist.

What the CMS Formulary Data Shows for sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]

Per the CMS 2026 Part D formulary file, sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] (RxNorm concept RXCUI 2621237, generic name sapropterin dihydrochloride) appears on 86 distinct formulary files spanning 1,593 Medicare Part D plan offerings - 31.5% of enrollable Part D products, selective placement; verify formulary inclusion before enrolling. Tier placement ranges from Tier 1 to Tier 5, with a cross-plan average of Tier 4.3.

Real-world access to sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] depends on utilization management as much as tier placement: 98.8% of covering formularies require prior authorization. 0% require step therapy. 0% apply quantity limits.

Historical spending context from the CMS Medicare Part D Drug Spending Dashboard shows 137 Part D beneficiaries filled sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] in 2023, with total plan-and-beneficiary spending of $14,682,881 and an average per-beneficiary annual cost of $107,174.32. The plan-by-plan detail below lists exactly which PDP and MA-PD contracts carry sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] today.

Coverage Details

Formularies covering
86
Plans covering
1,593
Coverage rate
31.5%
Tier range
Tier 1 – Tier 5
Average tier
Tier 4, Non-Preferred

Restrictions

Prior authorization required
98.8% of formularies
Step therapy required
0% of formularies
Quantity limits
0% of formularies

2023 Medicare Spending

Beneficiaries
137
Total spending
$14,682,881
Avg per beneficiary
$107,174.32

Tier Distribution Across Plans

32 plans
Tier 1, Preferred Generic
42 plans
Tier 4, Non-Preferred
26 plans
Tier 5, Specialty

Medicare Advantage Plans (MA-PD) Covering sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]

100 Medicare Advantage plans with Part D drug coverage include this drug.

Plan Insurer Tier PA Premium States
Florida Complete Care-Duals VIP (HMO-POS D-SNP) Hpmp OF Florida, Inc. T1 Yes $0 FL
Mercy Care Advantage (HMO D-SNP) Mercy Care T1 Yes $0 AZ
Mercy Care Advantage (HMO D-SNP) Mercy Care T1 Yes $0 AZ
Mercy Care Advantage (HMO D-SNP) Mercy Care T1 Yes $0 AZ
Elderplan Plus Long-Term Care (HMO-POS D-SNP) Elderplan, Inc. T1 Yes $0 NY
Health Choice Pathway (HMO D-SNP) Health Choice Arizona, Inc. T1 Yes $0 AZ
Healthfirst CompleteCare (HMO D-SNP) Healthfirst Health Plan, Inc. T1 Yes $0 NY
IMCare Classic (HMO D-SNP) Itasca Medical Care T1 Yes $0 MN
Johns Hopkins Advantage MD D-SNP (HMO D-SNP) Hopkins Health Advantage, Inc. T1 Yes $0 MD
MetroPlus UltraCare (HMO D-SNP) Metroplus Health Plan, Inc. T1 Yes $0 NY
Senior Whole Health SCO (HMO D-SNP) Senior Whole Health, LLC T1 Yes $0 MA
Senior Whole Health SCO NHC (HMO D-SNP) Senior Whole Health, LLC T1 Yes $0 MA
Molina One Care (HMO D-SNP) Senior Whole Health, LLC T1 Yes $0 MA
CCA One Care (HMO D-SNP) Commonwealth Care Alliance, Inc. T1 Yes $0 MA
CCA Senior Care Options (HMO D-SNP) Commonwealth Care Alliance, Inc. T1 Yes $0 MA
CalOptima Health OneCare Complete (HMO D-SNP) Orange County Health Authority T1 Yes $0 CA
Mass General Brigham SCO (HMO D-SNP) Mass General Brigham Health Plan, Inc T1 Yes $0 MA
Mass General Brigham One Care (HMO D-SNP) Mass General Brigham Health Plan, Inc T1 Yes $0 MA
Highmark Wholecare Medicare Assured Diamond (HMO D-SNP) Gateway Health Plan, Inc. T1 Yes $0 PA
Highmark Wholecare Medicare Assured Diamond (HMO D-SNP) Gateway Health Plan, Inc. T1 Yes $0 PA
Show the next 30 plans
Highmark Health Options Duals (HMO D-SNP) Highmark Health Options West Virginia Inc. T1 Yes $0 WV
Highmark Health Options Duals (HMO D-SNP) Highmark Bcbsd, Inc. T1 Yes $0 DE
Florida Complete Care (HMO I-SNP) Hpmp OF Florida, Inc. T1 Yes $4.80 FL
Florida Complete Care- In The Community (HMO-POS I-SNP) Hpmp OF Florida, Inc. T1 Yes $4.80 FL
Highmark Wholecare Medicare Assured Ruby (HMO D-SNP) Gateway Health Plan, Inc. T1 Yes $13.10 PA
Highmark Wholecare Medicare Assured Ruby (HMO D-SNP) Gateway Health Plan, Inc. T1 Yes $17.60 PA
Elderplan For Medicaid Beneficiaries (HMO-POS D-SNP) Elderplan, Inc. T1 Yes $22.70 NY
VIVA Medicare Extra Value (HMO D-SNP) Viva Health, Inc. T1 Yes $27.70 AL
VIVA Medicare Extra Care (HMO D-SNP) Viva Health, Inc. T1 Yes $27.70 AL
Highmark Health Options Duals Select (HMO D-SNP) Highmark Bcbsd, Inc. T1 Yes $31.20 DE
Elderplan Advantage For Nursing Home Residents (HMO-POS I-SNP) Elderplan, Inc. T1 Yes $44.80 NY
MetroPlus Platinum Plan (HMO) Metroplus Health Plan, Inc. T1 Yes $58.80 NY
Freedom VIP Care (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Savings (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Savings (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Rewards (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Rewards (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Optimum Diamond Rewards (HMO C-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Optimum Diamond Savings (HMO C-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Optimum Diamond Rewards (HMO C-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Optimum Diamond (HMO C-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Freedom Medi-Medi Partial (HMO D-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom Medi-Medi Full (HMO D-SNP) Freedom Health, Inc. T4 Yes $0 FL
Optimum Emerald Partial (HMO D-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Optimum Emerald Full (HMO D-SNP) Optimum Healthcare, Inc. T4 Yes $0 FL
Freedom Medicare Plan Rx (HMO) Freedom Health, Inc. T4 Yes $0 FL
Freedom Medicare Plan Rx (HMO) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Savings COPD (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom VIP Savings COPD (HMO C-SNP) Freedom Health, Inc. T4 Yes $0 FL
Freedom Platinum Plan Rx (HMO) Freedom Health, Inc. T4 Yes $0 FL

Showing top 50 of 100 plans.

Frequently Asked Questions

Is sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] covered by Medicare Part D?

Yes, sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] is covered by 1,593 Medicare Part D plans (31.5% of all Part D formularies).

What tier is sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] on Medicare Part D plans?

sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] averages Tier 4.3 across Part D plans, ranging from Tier 1 to Tier 5.

Does sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] require prior authorization?

98.8% of Part D formularies require prior authorization for sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]. Step therapy: 0%. Quantity limits: 0%.

How much does Medicare spend on sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor]?

In 2023, total Medicare Part D spending on sapropterin dihydrochloride 500 MG Powder for Oral Solution [Javygtor] was $14,682,881, covering 137 beneficiaries. The average spend per beneficiary was $107,174.32.

Nationwide similar Part D drugs

Data-derived peers across the CMS Part D formulary extract: nearest average tier placement and nearest prior-authorization rate. Not therapeutic alternatives or same-generic strengths.

Data sourced from the Centers for Medicare & Medicaid Services (CMS). See our methodology for details. Retrieved and formatted by PlainMedicare