Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
quinapril 40 MG Oral Tablet quinapril	4,951	97.7%	T2	0%	44,327
sodium polystyrene sulfonate 250 MG/ML Oral Suspension [SPS] sodium polystyrene sulfonate	4,951	97.7%	T3	0%	29,272
hydrochlorothiazide 12.5 MG / irbesartan 150 MG Oral Tablet hydrochlorothiazide	4,950	97.7%	T2	0%	4,902,174
hydrochlorothiazide 12.5 MG / irbesartan 300 MG Oral Tablet hydrochlorothiazide	4,950	97.7%	T2	0%	4,902,174
enalapril maleate 5 MG / hydrochlorothiazide 12.5 MG Oral Tablet enalapril maleate	4,950	97.7%	T2	0%	482,684
acetic acid 20 MG/ML Otic Solution acetic acid	4,950	97.7%	T2	0%	43,136
24 HR diltiazem hydrochloride 420 MG Extended Release Oral Capsule diltiazem hydrochloride	4,950	97.7%	T2	0%	-
benazepril hydrochloride 20 MG / hydrochlorothiazide 12.5 MG Oral Tablet benazepril hydrochloride	4,949	97.7%	T2	0%	540,761
benazepril hydrochloride 5 MG / hydrochlorothiazide 6.25 MG Oral Tablet benazepril hydrochloride	4,949	97.7%	T2	0%	540,761
benazepril hydrochloride 20 MG / hydrochlorothiazide 25 MG Oral Tablet benazepril hydrochloride	4,949	97.7%	T2	0%	540,761
benazepril hydrochloride 10 MG / hydrochlorothiazide 12.5 MG Oral Tablet benazepril hydrochloride	4,949	97.7%	T2	0%	540,761
amylase 30000 UNT / lipase 6000 UNT / protease 19000 UNT Delayed Release Oral Capsule [Creon] amylase	4,948	97.7%	T3	0.3%	185,325
amylase 60000 UNT / lipase 12000 UNT / protease 38000 UNT Delayed Release Oral Capsule [Creon] amylase	4,948	97.7%	T3	0.3%	185,325
amylase 15000 UNT / lipase 3000 UNT / protease 9500 UNT Delayed Release Oral Capsule [Creon] amylase	4,948	97.7%	T3	0.3%	185,325
amylase 120000 UNT / lipase 24000 UNT / protease 76000 UNT Delayed Release Oral Capsule [Creon] amylase	4,948	97.7%	T3	0.3%	185,325
amylase 180000 UNT / lipase 36000 UNT / protease 114000 UNT Delayed Release Oral Capsule [Creon] amylase	4,948	97.7%	T3	0.3%	185,325
captopril 50 MG Oral Tablet captopril	4,948	97.7%	T2	0%	18,382
captopril 100 MG Oral Tablet captopril	4,948	97.7%	T2	0%	18,382
degarelix 120 MG Injection [Firmagon] degarelix	4,948	97.7%	T4	94.4%	384
upadacitinib 1 MG/ML Oral Solution [Rinvoq] upadacitinib	4,947	97.6%	T4	98.7%	21,424
tretinoin 1 MG/ML Topical Cream tretinoin	4,946	97.6%	T3	91.9%	91,688
bacitracin zinc 0.4 UNT/MG / hydrocortisone acetate 0.01 MG/MG / neomycin sulfate 0.0035 MG/MG / polymyxin B sulfate 10 UNT/MG Ophthalmic Ointment bacitracin zinc	4,946	97.6%	T2	0%	14,794
heparin sodium, porcine 20000 UNT/ML Injectable Solution heparin sodium, porcine	4,946	97.6%	T2	27.6%	13,864
nilotinib 150 MG Oral Capsule nilotinib	4,946	97.6%	T4	99.3%	2,961
nilotinib 200 MG Oral Capsule nilotinib	4,946	97.6%	T4	99.3%	2,961
nilotinib 50 MG Oral Capsule nilotinib	4,946	97.6%	T4	99.3%	2,961
mesalamine 66.7 MG/ML Enema mesalamine	4,944	97.6%	T3	0%	95,185
acetylcysteine 100 MG/ML Inhalation Solution acetylcysteine	4,944	97.6%	T2	99.7%	4,830
acetylcysteine 200 MG/ML Inhalation Solution acetylcysteine	4,944	97.6%	T2	99.7%	4,830
azithromycin 20 MG/ML Oral Suspension azithromycin	4,942	97.5%	T2	0%	5,970,026
carteolol hydrochloride 10 MG/ML Ophthalmic Solution carteolol hydrochloride	4,942	97.5%	T2	0%	5,536
{21 (ethinyl estradiol 0.03 MG / levonorgestrel 0.15 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Portia 28 Day] ethinyl estradiol	4,942	97.5%	T2	0%	-
NDA019430 0.3 ML epinephrine 1 MG/ML Auto-Injector NDA019430	4,942	97.5%	T2	0%	-
2 ML penicillin G benzathine 600000 UNT/ML Prefilled Syringe [Bicillin L-A] penicillin G benzathine	4,941	97.5%	T3	8.1%	2,770
{21 (ethinyl estradiol 0.035 MG / norgestimate 0.25 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Sprintec 28 Day] ethinyl estradiol	4,941	97.5%	T2	0%	-
24 HR felodipine 2.5 MG Extended Release Oral Tablet felodipine	4,941	97.5%	T2	0%	-
olmesartan medoxomil 40 MG Oral Tablet olmesartan medoxomil	4,940	97.5%	T2	0%	773,533
olmesartan medoxomil 5 MG Oral Tablet olmesartan medoxomil	4,940	97.5%	T2	0%	773,533
olmesartan medoxomil 20 MG Oral Tablet olmesartan medoxomil	4,940	97.5%	T2	0%	773,533
warfarin sodium 1 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 2 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 2.5 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 3 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 4 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 5 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 6 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 7.5 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
warfarin sodium 10 MG Oral Tablet [Jantoven] warfarin sodium	4,939	97.5%	T1	0%	942,245
fluocinonide 0.0005 MG/MG Topical Gel fluocinonide	4,939	97.5%	T3	0%	379,768
norethindrone acetate 5 MG Oral Tablet [Gallifrey] norethindrone acetate	4,939	97.5%	T2	0%	15,646
Emollient clobetasol propionate 0.5 MG/ML Topical Cream Emollient clobetasol propionate	4,939	97.5%	T3	0%	-
{56 (elexacaftor 50 MG / ivacaftor 37.5 MG / tezacaftor 25 MG Oral Tablet) / 28 (ivacaftor 75 MG Oral Tablet) } Pack [Trikafta (50 MG / 37.5 MG / 25 MG; 75 MG)] elexacaftor	4,938	97.5%	T4	99.4%	-
nystatin 100 UNT/MG Topical Powder [Nystop] nystatin	4,937	97.4%	T2	0%	1,571,473
lactulose 667 MG/ML Oral Solution [Constulose] lactulose	4,937	97.4%	T2	0%	526,962
24 HR quetiapine 50 MG Extended Release Oral Tablet quetiapine	4,937	97.4%	T3	30.8%	-
ammonium lactate 120 MG/ML Topical Lotion ammonium lactate	4,935	97.4%	T2	0.3%	491,025
{21 (ethinyl estradiol 0.035 MG / ethynodiol diacetate 1 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Kelnor 1/35 28 Day] ethinyl estradiol	4,935	97.4%	T2	0%	-
timolol 5 MG Oral Tablet timolol	4,934	97.4%	T3	0%	6,978
adefovir dipivoxil 10 MG Oral Tablet adefovir dipivoxil	4,934	97.4%	T3	5.2%	418
NDA019430 0.3 ML epinephrine 0.5 MG/ML Auto-Injector NDA019430	4,933	97.4%	T2	0%	-
24 HR quetiapine 200 MG Extended Release Oral Tablet quetiapine	4,933	97.4%	T3	30.9%	-
24 HR quetiapine 300 MG Extended Release Oral Tablet quetiapine	4,933	97.4%	T3	30.9%	-
24 HR quetiapine 400 MG Extended Release Oral Tablet quetiapine	4,933	97.4%	T3	30.9%	-
24 HR quetiapine 150 MG Extended Release Oral Tablet quetiapine	4,933	97.4%	T3	30.9%	-
ibandronic acid 150 MG Oral Tablet ibandronic acid	4,933	97.4%	T2	16.9%	-
2 ML clindamycin 150 MG/ML Injection clindamycin	4,932	97.3%	T3	8.8%	-
deferasirox 90 MG Oral Tablet deferasirox	4,930	97.3%	T2	93.7%	3,436
{3 (azithromycin 500 MG Oral Tablet) } Pack azithromycin	4,929	97.3%	T1	0%	-
finerenone 40 MG Oral Tablet [Kerendia] finerenone	4,928	97.3%	T3	75.2%	63,625
30 ACTUAT fluticasone furoate 0.1 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler [Breo]	4,927	97.2%	T3	0%	-
30 ACTUAT fluticasone furoate 0.2 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler [Breo]	4,927	97.2%	T3	0%	-
21 DAY ethinyl estradiol 0.000625 MG/HR / etonogestrel 0.005 MG/HR Vaginal System	4,927	97.2%	T2	0%	-
{21 (desogestrel 0.15 MG / ethinyl estradiol 0.03 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Apri 28 Day] desogestrel	4,926	97.2%	T2	0%	-
ampicillin 100 MG/ML Injectable Solution ampicillin	4,925	97.2%	T3	10.3%	3,864
fluocinonide 0.5 MG/ML Topical Cream fluocinonide	4,923	97.2%	T2	0%	379,768
morphine sulfate 2 MG/ML Oral Solution morphine sulfate	4,923	97.2%	T2	1%	255,247
heparin sodium, porcine 1000 UNT/ML Injectable Solution heparin sodium, porcine	4,923	97.2%	T2	27.5%	13,864
vancomycin 750 MG Injection vancomycin	4,921	97.1%	T3	0%	161,077
24 HR diltiazem hydrochloride 360 MG Extended Release Oral Capsule diltiazem hydrochloride	4,920	97.1%	T2	0%	-
meclizine hydrochloride 12.5 MG Oral Tablet meclizine hydrochloride	4,919	97.1%	T2	20.7%	1,294,975
morphine sulfate 4 MG/ML Oral Solution morphine sulfate	4,919	97.1%	T2	1%	255,247
ambrisentan 5 MG Oral Tablet ambrisentan	4,918	97.1%	T4	98.9%	6,456
ambrisentan 10 MG Oral Tablet ambrisentan	4,918	97.1%	T4	98.9%	6,456
doxycycline hyclate 100 MG Injection [Doxy] doxycycline hyclate	4,917	97%	T3	11.3%	4,121,486
hydrocortisone 25 MG/ML Topical Cream [Procto-Med] hydrocortisone	4,917	97%	T2	0%	1,257,661
{21 (ethinyl estradiol 0.02 MG / norethindrone acetate 1 MG Oral Tablet) / 7 (ferrous fumarate 75 MG Oral Tablet) } Pack [Junel Fe 1/20 28 Day] ethinyl estradiol	4,916	97%	T2	0%	-
fenofibrate 134 MG Oral Capsule fenofibrate	4,915	97%	T2	0%	500,170
fenofibrate 67 MG Oral Capsule fenofibrate	4,915	97%	T2	0%	500,170
sodium zirconium cyclosilicate 5000 MG Powder for Oral Suspension [Lokelma] sodium zirconium cyclosilicate	4,915	97%	T3	11.5%	94,774
sodium zirconium cyclosilicate 10000 MG Powder for Oral Suspension [Lokelma] sodium zirconium cyclosilicate	4,915	97%	T3	11.5%	94,774
1 ML glatiramer acetate 40 MG/ML Prefilled Syringe glatiramer acetate	4,914	97%	T4	81.4%	-
hydrochlorothiazide 12.5 MG / olmesartan medoxomil 20 MG Oral Tablet hydrochlorothiazide	4,913	97%	T2	0%	4,902,174
hydrochlorothiazide 12.5 MG / olmesartan medoxomil 40 MG Oral Tablet hydrochlorothiazide	4,913	97%	T2	0%	4,902,174
hydrochlorothiazide 25 MG / olmesartan medoxomil 40 MG Oral Tablet hydrochlorothiazide	4,913	97%	T2	0%	4,902,174
Microencapsulated potassium chloride 10 MEQ Extended Release Oral Tablet [Klor-Con] Microencapsulated potassium chloride	4,913	97%	T2	0%	24,541
Microencapsulated potassium chloride 20 MEQ Extended Release Oral Tablet [Klor-Con] Microencapsulated potassium chloride	4,913	97%	T2	0%	24,541
{28 (elexacaftor 80 MG / ivacaftor 60 MG / tezacaftor 40 MG Oral Granules) / 28 (ivacaftor 59.5 MG Oral Granules) } Pack [Trikafta (80 MG / 40 MG / 60 MG; 59.5 MG) Granules] elexacaftor	4,912	96.9%	T4	98.7%	-
{28 (elexacaftor 100 MG / ivacaftor 75 MG / tezacaftor 50 MG Oral Granules) / 28 (ivacaftor 75 MG Oral Granules) } Pack [Trikafta (100 MG / 50 MG / 75 MG; 75 MG) Granules] elexacaftor	4,912	96.9%	T4	98.7%	-
temazepam 15 MG Oral Capsule temazepam	4,911	96.9%	T2	29%	394,771
temazepam 30 MG Oral Capsule temazepam	4,911	96.9%	T2	29%	394,771

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team