Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
collagenase 0.25 UNT/MG Topical Ointment [Santyl] collagenase	5,000	98.7%	T3	27.6%	148,983
{21 (prednisone 5 MG Oral Tablet) } Pack prednisone	4,999	98.7%	T2	0%	-
{21 (prednisone 10 MG Oral Tablet) } Pack prednisone	4,999	98.7%	T2	0%	-
NDA021457 200 ACTUAT albuterol 0.09 MG/ACTUAT Metered Dose Inhaler NDA021457	4,999	98.7%	T2	0%	-
24 HR niacin 500 MG Extended Release Oral Tablet niacin	4,999	98.7%	T2	0.3%	-
alprazolam 0.25 MG Oral Tablet alprazolam	4,998	98.6%	T2	6.4%	2,265,351
alprazolam 0.5 MG Oral Tablet alprazolam	4,998	98.6%	T2	6.4%	2,265,351
alprazolam 1 MG Oral Tablet alprazolam	4,998	98.6%	T2	6.4%	2,265,351
alprazolam 2 MG Oral Tablet alprazolam	4,998	98.6%	T2	6.4%	2,265,351
24 HR propranolol hydrochloride 60 MG Extended Release Oral Capsule propranolol hydrochloride	4,998	98.6%	T2	0%	-
24 HR propranolol hydrochloride 80 MG Extended Release Oral Capsule propranolol hydrochloride	4,998	98.6%	T2	0%	-
24 HR propranolol hydrochloride 120 MG Extended Release Oral Capsule propranolol hydrochloride	4,998	98.6%	T2	0%	-
24 HR propranolol hydrochloride 160 MG Extended Release Oral Capsule propranolol hydrochloride	4,998	98.6%	T2	0%	-
1 ML testosterone cypionate 200 MG/ML Injection testosterone cypionate	4,997	98.6%	T2	69.4%	-
nitrofurantoin, macrocrystals 100 MG Oral Capsule nitrofurantoin, macrocrystals	4,995	98.6%	T2	0%	2,638,012
atovaquone 62.5 MG / proguanil hydrochloride 25 MG Oral Tablet atovaquone	4,995	98.6%	T3	0%	21,829
3.5 ML paliperidone palmitate 312 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,995	98.6%	T4	7%	2,964
5 ML paliperidone palmitate 312 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,995	98.6%	T4	7%	2,964
1 ML penicillin G benzathine 600000 UNT/ML Prefilled Syringe [Bicillin L-A] penicillin G benzathine	4,994	98.6%	T3	8%	2,770
hydroxyzine hydrochloride 10 MG Oral Tablet hydroxyzine hydrochloride	4,993	98.5%	T2	53.1%	1,319,270
aprepitant 40 MG Oral Capsule aprepitant	4,993	98.5%	T3	99.7%	4,705
oxybutynin chloride 1 MG/ML Oral Solution oxybutynin chloride	4,992	98.5%	T2	0.6%	881,680
Augmented betamethasone 0.0005 MG/MG Topical Ointment Augmented betamethasone	4,992	98.5%	T3	0%	-
1 ML naloxone hydrochloride 0.4 MG/ML Cartridge naloxone hydrochloride	4,991	98.5%	T2	0%	-
famciclovir 125 MG Oral Tablet famciclovir	4,989	98.5%	T2	0%	60,825
famciclovir 250 MG Oral Tablet famciclovir	4,989	98.5%	T2	0%	60,825
famciclovir 500 MG Oral Tablet famciclovir	4,989	98.5%	T2	0%	60,825
{48 (prednisone 5 MG Oral Tablet) } Pack prednisone	4,989	98.5%	T2	0%	-
{48 (prednisone 10 MG Oral Tablet) } Pack prednisone	4,989	98.5%	T2	0%	-
nafcillin 100 MG/ML Injectable Solution nafcillin	4,989	98.5%	T3	9.2%	-
leuprolide acetate 5 MG/ML Injectable Solution leuprolide acetate	4,988	98.4%	T3	86%	8,570
fluocinolone acetonide 0.00025 MG/MG Topical Ointment fluocinolone acetonide	4,987	98.4%	T2	0%	80,799
disulfiram 500 MG Oral Tablet disulfiram	4,986	98.4%	T3	0%	8,729
1 ML risankizumab-rzaa 150 MG/ML Prefilled Syringe [Skyrizi] risankizumab-rzaa	4,986	98.4%	T4	98.4%	-
1.2 ML risankizumab-rzaa 150 MG/ML Cartridge [Skyrizi] risankizumab-rzaa	4,986	98.4%	T4	98.4%	-
2.4 ML risankizumab-rzaa 150 MG/ML Cartridge [Skyrizi] risankizumab-rzaa	4,986	98.4%	T4	98.4%	-
1 ML risankizumab-rzaa 150 MG/ML Auto-Injector [Skyrizi] risankizumab-rzaa	4,986	98.4%	T4	98.4%	-
amantadine hydrochloride 10 MG/ML Oral Solution amantadine hydrochloride	4,985	98.4%	T2	0%	98,048
linezolid 20 MG/ML Oral Suspension linezolid	4,984	98.4%	T4	21.1%	88,286
0.88 ML paliperidone palmitate 310 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,984	98.4%	T4	6.4%	2,964
1.32 ML paliperidone palmitate 311 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,984	98.4%	T4	6.4%	2,964
1.75 ML paliperidone palmitate 312 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,984	98.4%	T4	6.4%	2,964
2.63 ML paliperidone palmitate 311 MG/ML Prefilled Syringe [Invega] paliperidone palmitate	4,984	98.4%	T4	6.4%	2,964
{2 (480 ML) (magnesium sulfate 0.0277 MEQ/ML / potassium sulfate 0.0374 MEQ/ML / sodium sulfate 0.257 MEQ/ML Oral Solution) } Pack	4,983	98.3%	T3	0%	-
NDA020503 200 ACTUAT albuterol 0.09 MG/ACTUAT Metered Dose Inhaler NDA020503	4,981	98.3%	T2	0%	-
{21 (ethinyl estradiol 0.02 MG / levonorgestrel 0.1 MG Oral Tablet) / 7 (inert ingredients 1 MG Oral Tablet) } Pack [Aviane 28] ethinyl estradiol	4,977	98.2%	T2	0%	-
24 HR levetiracetam 500 MG Extended Release Oral Tablet levetiracetam	4,977	98.2%	T2	0%	-
24 HR levetiracetam 750 MG Extended Release Oral Tablet levetiracetam	4,977	98.2%	T2	0%	-
Sugar-Free cholestyramine resin 4000 MG Powder for Oral Suspension [Prevalite] Sugar-Free cholestyramine resin	4,975	98.2%	T3	0%	23,744
24 HR upadacitinib 45 MG Extended Release Oral Tablet [Rinvoq] upadacitinib	4,975	98.2%	T4	98.7%	21,424
24 HR upadacitinib 15 MG Extended Release Oral Tablet [Rinvoq] upadacitinib	4,975	98.2%	T4	98.7%	21,424
24 HR upadacitinib 30 MG Extended Release Oral Tablet [Rinvoq] upadacitinib	4,975	98.2%	T4	98.7%	21,424
magnesium sulfate 0.0277 MEQ/ML / potassium sulfate 0.0374 MEQ/ML / sodium sulfate 0.257 MEQ/ML Oral Solution magnesium sulfate	4,975	98.2%	T3	0%	929
prasugrel 10 MG Oral Tablet prasugrel	4,972	98.1%	T2	0%	85,432
prasugrel 5 MG Oral Tablet prasugrel	4,972	98.1%	T2	0%	85,432
nafcillin 2000 MG Injection nafcillin	4,972	98.1%	T3	8.8%	-
4 ML penicillin G benzathine 600000 UNT/ML Prefilled Syringe [Bicillin L-A] penicillin G benzathine	4,969	98.1%	T3	8%	2,770
fluocinolone acetonide 0.25 MG/ML Topical Cream fluocinolone acetonide	4,967	98%	T3	0%	80,799
cefazolin 200 MG/ML Injectable Solution cefazolin	4,967	98%	T3	0.7%	19,643
24 HR felodipine 5 MG Extended Release Oral Tablet felodipine	4,966	98%	T2	0%	-
24 HR felodipine 10 MG Extended Release Oral Tablet felodipine	4,966	98%	T2	0%	-
azithromycin 40 MG/ML Oral Suspension azithromycin	4,964	98%	T2	0%	5,970,026
galantamine 4 MG Oral Tablet galantamine	4,964	98%	T3	0%	24,725
galantamine 8 MG Oral Tablet galantamine	4,964	98%	T3	0%	24,725
galantamine 12 MG Oral Tablet galantamine	4,964	98%	T3	0%	24,725
24 HR galantamine hydrobromide 8 MG Extended Release Oral Capsule galantamine hydrobromide	4,964	98%	T3	0%	-
24 HR galantamine hydrobromide 16 MG Extended Release Oral Capsule galantamine hydrobromide	4,964	98%	T3	0%	-
24 HR galantamine hydrobromide 24 MG Extended Release Oral Capsule galantamine hydrobromide	4,964	98%	T3	0%	-
degarelix 80 MG Injection [Firmagon] degarelix	4,963	97.9%	T3	93.8%	384
1 ML heparin sodium, porcine 10000 UNT/ML Injection heparin sodium, porcine	4,961	97.9%	T2	26.9%	-
amoxicillin 50 MG/ML / clavulanate 12.5 MG/ML Oral Suspension amoxicillin	4,960	97.9%	T3	0%	6,202,496
nystatin 100 UNT/MG Topical Powder nystatin	4,959	97.9%	T2	0%	1,571,473
cefoxitin 200 MG/ML Injectable Solution cefoxitin	4,957	97.8%	T3	10.9%	390
fingolimod 0.5 MG Oral Capsule fingolimod	4,956	97.8%	T4	80.8%	2,875
prednisone 1 MG/ML Oral Solution prednisone	4,954	97.8%	T3	48.7%	7,163,637
amoxicillin 125 MG Chewable Tablet amoxicillin	4,954	97.8%	T2	0%	6,202,496
amoxicillin 250 MG Chewable Tablet amoxicillin	4,954	97.8%	T2	0%	6,202,496
flurbiprofen sodium 0.3 MG/ML Ophthalmic Solution flurbiprofen sodium	4,954	97.8%	T2	0%	8,299
dexamethasone 0.1 MG/ML Oral Solution dexamethasone	4,953	97.8%	T2	0%	850,184
morphine sulfate 20 MG/ML Oral Solution morphine sulfate	4,953	97.8%	T2	16.8%	255,247
6 ML clindamycin 150 MG/ML Injection clindamycin	4,953	97.8%	T3	9.8%	-
ibuprofen 800 MG Oral Tablet [Ibu] ibuprofen	4,952	97.7%	T1	0%	3,444,665
rivaroxaban 2.5 MG Oral Tablet [Xarelto] rivaroxaban	4,952	97.7%	T3	0%	1,324,165
loperamide hydrochloride 2 MG Oral Capsule loperamide hydrochloride	4,952	97.7%	T2	0%	389,634
pilocarpine hydrochloride 7.5 MG Oral Tablet pilocarpine hydrochloride	4,952	97.7%	T3	0%	91,595
leucovorin 15 MG Oral Tablet leucovorin	4,952	97.7%	T2	0%	26,004
vericiguat 2.5 MG Oral Tablet [Verquvo] vericiguat	4,952	97.7%	T3	68%	8,218
vericiguat 5 MG Oral Tablet [Verquvo] vericiguat	4,952	97.7%	T3	68%	8,218
tinidazole 500 MG Oral Tablet tinidazole	4,952	97.7%	T3	0%	6,633
ceftazidime 2000 MG Injection ceftazidime	4,952	97.7%	T3	7.9%	5,212
ceftaroline fosamil 400 MG Injection [Teflaro] ceftaroline fosamil	4,952	97.7%	T4	9.1%	887
30 ACTUAT fluticasone furoate 0.1 MG/ACTUAT / umeclidinium 0.0625 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler [Trelegy]	4,952	97.7%	T3	0%	-
solifenacin succinate 5 MG Oral Tablet solifenacin succinate	4,951	97.7%	T2	0.7%	301,190
solifenacin succinate 10 MG Oral Tablet solifenacin succinate	4,951	97.7%	T2	0.7%	301,190
fosinopril sodium 10 MG Oral Tablet fosinopril sodium	4,951	97.7%	T2	0%	50,736
fosinopril sodium 20 MG Oral Tablet fosinopril sodium	4,951	97.7%	T2	0%	50,736
fosinopril sodium 40 MG Oral Tablet fosinopril sodium	4,951	97.7%	T2	0%	50,736
quinapril 5 MG Oral Tablet quinapril	4,951	97.7%	T2	0%	44,327
quinapril 10 MG Oral Tablet quinapril	4,951	97.7%	T2	0%	44,327
quinapril 20 MG Oral Tablet quinapril	4,951	97.7%	T2	0%	44,327

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team