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Medicare Part D drugs starting with H

58 drugs start with H; 28 of them are on at least 90% of 2026 Part D formularies. Part D spending was highest for Humira in 2024: $5.6 billion, what plans and patients paid at the pharmacy before rebates.

Which drugs start with H?

By name; spending is what plans and patients paid at the pharmacy in 2024 (“no 2024 match”: no row of the CMS spending file can be tied to this product alone)
DrugPlans coveringUsual tierMedicare spending, 2024
Hadlima (adalimumab-bwwd)50.5%Tier 5$1 million
Haegarda (C1 esterase inhibitor, human)90.9%Tier 5$82 million
Hailey 24 Fe (ethinyl estradiol / norethindrone acetate)77.3%Tier 2$96 thousand
Hailey Fe (ethinyl estradiol / norethindrone acetate)88.2%Tier 2$96 thousand
Halcinonide0.2%Tier 4$1 million
Halobetasol propionate82.8%Tier 4$12 million
Haloperidol100%Tier 2$29 million
Haloperidol decanoate100%Tier 4$15 million
Harliku (nitisinone)3.1%Tier 5no 2024 match
Harvoni (ledipasvir / sofosbuvir)15.7%Tier 5$36 million
Havrix (hepatitis A vaccine)100%Tier 1$5 million
Heather (norethindrone)96.8%Tier 2$137 thousand
Hemady (dexamethasone)4.3%Tier 4$120 thousand
Hemiclor (chlorthalidone)0.4%Tier 4no 2024 match
Heparin sodium, porcine100%Tier 3$2 million
Heplisav-B (hepatitis B vaccine)100%Tier 1$877 thousand
Hernexeos (zongertinib)100%Tier 5no 2024 match
Hetlioz (tasimelteon)2.3%Tier 5$65 million
Hiberix (Hib vaccine)100%Tier 1$20 thousand
Horizant (gabapentin enacarbil)0.1%Tier 4$32 million
Humalog (insulin lispro)39.1%Tier 3$664 million
Humalog Mix (insulin lispro / insulin lispro protamine, human)36.5%Tier 3$73 million
Humatin (paromomycin)25.8%Tier 5$772 thousand
Humatrope (somatropin)2.6%Tier 5$6 million
Humira (adalimumab)54%Tier 5$5.6 billion
Humulin (insulin isophane, human / insulin, regular, human)40%Tier 3$32 million
Humulin N (insulin isophane, human)40%Tier 3$70 million
Humulin R (insulin, regular, human)94.9%Tier 3$317 million
Hydralazine hydrochloride100%Tier 1$82 million
Hydralazine hydrochloride / isosorbide dinitrate66.6%Tier 3$5 million
Hydrea (hydroxyurea)under 0.1%Tier 1$39 thousand
Hydrochlorothiazide100%Tier 1$81 million
Hydrochlorothiazide / irbesartan97.7%Tier 1$14 million
Hydrochlorothiazide / lisinopril100%Tier 1$47 million
Hydrochlorothiazide / losartan potassium100%Tier 1$80 million
Hydrochlorothiazide / metoprolol tartrate93.5%Tier 2$2 million
Hydrochlorothiazide / olmesartan medoxomil97%Tier 1$35 million
Hydrochlorothiazide / quinapril82%Tier 1$7 thousand
Hydrochlorothiazide / spironolactone99.5%Tier 2$8 million
Hydrochlorothiazide / telmisartan88.2%Tier 1$18 million
Show the other 18 drugs
DrugPlans coveringUsual tierMedicare spending, 2024
Hydrochlorothiazide / triamterene100%Tier 1$26 million
Hydrochlorothiazide / valsartan100%Tier 1$56 million
Hydrocodone bitartrate27.2%Tier 4$4 million
Hydrocodone bitartrate / ibuprofen87.9%Tier 3$2 million
Hydrocortisone100%Tier 1$45 million
Hydrocortisone / neomycin / polymyxin b100%Tier 3$25 million
Hydrocortisone acetate / pramoxine hydrochloride5%Tier 2$405 thousand
Hydrocortisone butyrate50%Tier 4$6 million
Hydrocortisone valerate69.1%Tier 2$1 million
Hydromorphone hydrochloride99.7%Tier 3$18 million
Hydroxychloroquine sulfate100%Tier 2$98 million
Hydroxyurea100%Tier 2$13 million
Hydroxyzine hydrochloride100%Tier 1$74 million
Hydroxyzine pamoate93.6%Tier 1$19 million
Hyftor (sirolimus)2.1%Tier 5$1 million
Hyrimoz (adalimumab-adaz)0.3%Tier 5$9 million
Hyrnuo (sevabertinib)100%Tier 5no 2024 match
Hyzaar (hydrochlorothiazide / losartan potassium)under 0.1%Tier 1$1 million

Source: CMS Part D formulary file, 2026 second quarter; CMS Medicare Part D Spending by Drug, 2024.

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