Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
enasidenib 50 MG Oral Tablet [Idhifa] enasidenib	5,067	100%	T4	99.4%	813
enasidenib 100 MG Oral Tablet [Idhifa] enasidenib	5,067	100%	T4	99.4%	813
lopinavir 80 MG/ML / ritonavir 20 MG/ML Oral Solution [Kaletra] lopinavir	5,067	100%	T4	0%	749
lopinavir 200 MG / ritonavir 50 MG Oral Tablet lopinavir	5,067	100%	T3	0%	749
lopinavir 100 MG / ritonavir 25 MG Oral Tablet lopinavir	5,067	100%	T3	0%	749
bupropion hydrochloride 100 MG Oral Tablet bupropion hydrochloride	5,067	100%	T2	0%	741
bupropion hydrochloride 75 MG Oral Tablet bupropion hydrochloride	5,067	100%	T2	0%	741
bupropion hydrochloride 105 MG / dextromethorphan hydrobromide 45 MG Extended Release Oral Tablet [Auvelity] bupropion hydrochloride	5,067	100%	T4	42.7%	741
asenapine 5 MG Sublingual Tablet asenapine	5,067	100%	T3	21.5%	714
asenapine 10 MG Sublingual Tablet asenapine	5,067	100%	T3	21.5%	714
asenapine 2.5 MG Sublingual Tablet asenapine	5,067	100%	T3	21.5%	714
24 HR asenapine 0.158 MG/HR Transdermal System [Secuado] asenapine	5,067	100%	T4	38.5%	714
24 HR asenapine 0.238 MG/HR Transdermal System [Secuado] asenapine	5,067	100%	T4	38.5%	714
24 HR asenapine 0.317 MG/HR Transdermal System [Secuado] asenapine	5,067	100%	T4	38.5%	714
BCG, live, Tice strain 50 MG Injection BCG, live, Tice strain	5,067	100%	T2	0%	709
0.5 ML Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML Prefilled Syringe [Trumenba] Neisseria	5,067	100%	T2	1.8%	704
asciminib 20 MG Oral Tablet [Scemblix] asciminib	5,067	100%	T4	99.4%	704
asciminib 40 MG Oral Tablet [Scemblix] asciminib	5,067	100%	T4	99.4%	704
asciminib 100 MG Oral Tablet [Scemblix] asciminib	5,067	100%	T4	99.4%	704
quinidine sulfate 300 MG Oral Tablet quinidine sulfate	5,067	100%	T2	0%	676
quinidine sulfate 200 MG Oral Tablet quinidine sulfate	5,067	100%	T2	0%	676
tigecycline 50 MG Injection tigecycline	5,067	100%	T3	13.9%	655
pirtobrutinib 50 MG Oral Tablet [Jaypirca] pirtobrutinib	5,067	100%	T4	99.1%	647
pirtobrutinib 100 MG Oral Tablet [Jaypirca] pirtobrutinib	5,067	100%	T4	99.1%	647
0.5 ML Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML Injection [Hiberix] Haemophilus influenzae type b strain	5,067	100%	T2	0%	639
naltrexone hydrochloride 50 MG Oral Tablet naltrexone hydrochloride	5,067	100%	T2	0%	635
lorlatinib 25 MG Oral Tablet [Lorbrena] lorlatinib	5,067	100%	T4	99.4%	605
lorlatinib 100 MG Oral Tablet [Lorbrena] lorlatinib	5,067	100%	T4	99.4%	605
azacitidine 200 MG Oral Tablet [Onureg] azacitidine	5,067	100%	T4	99.4%	589
azacitidine 300 MG Oral Tablet [Onureg] azacitidine	5,067	100%	T4	99.4%	589
rucaparib 200 MG Oral Tablet [Rubraca] rucaparib	5,067	100%	T4	99.4%	556
rucaparib 250 MG Oral Tablet [Rubraca] rucaparib	5,067	100%	T4	99.4%	556
rucaparib 300 MG Oral Tablet [Rubraca] rucaparib	5,067	100%	T4	99.4%	556
0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide meningococcal protein conjugate vaccine 0.265 MG/ML Injection [PedvaxHIB] Haemophilus	5,067	100%	T2	0%	545
diazoxide 50 MG/ML Oral Suspension diazoxide	5,067	100%	T4	0.3%	525
thalidomide 50 MG Oral Capsule [Thalomid] thalidomide	5,067	100%	T4	87%	500
thalidomide 100 MG Oral Capsule [Thalomid] thalidomide	5,067	100%	T4	87%	500
sonidegib 200 MG Oral Capsule [Odomzo] sonidegib	5,067	100%	T4	99.4%	495
mechlorethamine 0.00016 MG/MG Topical Gel [Valchlor] mechlorethamine	5,067	100%	T4	96.1%	487
momelotinib 200 MG Oral Tablet [Ojjaara] momelotinib	5,067	100%	T4	99.4%	486
momelotinib 150 MG Oral Tablet [Ojjaara] momelotinib	5,067	100%	T4	99.4%	486
momelotinib 100 MG Oral Tablet [Ojjaara] momelotinib	5,067	100%	T4	99.4%	486
zidovudine 300 MG Oral Tablet zidovudine	5,067	100%	T2	0%	481
zidovudine 10 MG/ML Oral Solution zidovudine	5,067	100%	T2	0%	481
zidovudine 100 MG Oral Capsule zidovudine	5,067	100%	T3	0%	481
selpercatinib 40 MG Oral Tablet [Retevmo] selpercatinib	5,067	100%	T4	99.4%	479
selpercatinib 160 MG Oral Tablet [Retevmo] selpercatinib	5,067	100%	T4	99.4%	479
selpercatinib 80 MG Oral Tablet [Retevmo] selpercatinib	5,067	100%	T4	99.4%	479
selpercatinib 120 MG Oral Tablet [Retevmo] selpercatinib	5,067	100%	T4	99.4%	479
belzutifan 40 MG Oral Tablet [Welireg] belzutifan	5,067	100%	T4	99.1%	453
neratinib 40 MG Oral Tablet [Nerlynx] neratinib	5,067	100%	T4	99.4%	452
amoxapine 25 MG Oral Tablet amoxapine	5,067	100%	T3	23.9%	450
amoxapine 50 MG Oral Tablet amoxapine	5,067	100%	T3	23.9%	450
amoxapine 100 MG Oral Tablet amoxapine	5,067	100%	T3	23.9%	450
amoxapine 150 MG Oral Tablet amoxapine	5,067	100%	T3	23.9%	450
adagrasib 200 MG Oral Tablet [Krazati] adagrasib	5,067	100%	T4	99.4%	443
maribavir 200 MG Oral Tablet [Livtencity] maribavir	5,067	100%	T4	77%	433
fedratinib 100 MG Oral Capsule [Inrebic] fedratinib	5,067	100%	T4	99.4%	421
cefoxitin 1000 MG Injection cefoxitin	5,067	100%	T3	10%	390
cefoxitin 2000 MG Injection cefoxitin	5,067	100%	T3	10%	390
crizotinib 20 MG Oral Pellet [Xalkori] crizotinib	5,067	100%	T4	99.4%	387
crizotinib 50 MG Oral Pellet [Xalkori] crizotinib	5,067	100%	T4	99.4%	387
crizotinib 150 MG Oral Pellet [Xalkori] crizotinib	5,067	100%	T4	99.4%	387
crizotinib 250 MG Oral Capsule [Xalkori] crizotinib	5,067	100%	T4	99.4%	387
crizotinib 200 MG Oral Capsule [Xalkori] crizotinib	5,067	100%	T4	99.4%	387
telotristat ethyl 250 MG Oral Tablet [Xermelo] telotristat ethyl	5,067	100%	T4	99.1%	367
0.5 ML acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 58 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 14 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 52 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Pentacel] acellular pertussis vaccine, inactivated	5,067	100%	T2	0%	363
midostaurin 25 MG Oral Capsule [Rydapt] midostaurin	5,067	100%	T4	99.4%	347
etonogestrel 68 MG Drug Implant [Nexplanon] etonogestrel	5,067	100%	T3	0.6%	346
1 ML ropeginterferon alfa-2b-njft 0.5 MG/ML Prefilled Syringe [Besremi] ropeginterferon	5,067	100%	T4	99.1%	333
lenacapavir 300 MG Oral Tablet [Sunlenca] lenacapavir	5,067	100%	T4	0%	320
0.5 ML measles virus vaccine live, attenuated Schwarz strain 5024 UNT/ML / mumps virus vaccine live, RIT-4385 strain 31684 UNT/ML / rubella virus vaccine live (Wistar RA 27-3 strain) 3990 UNT/ML Injection [Priorix] measles virus vaccine live, attenuated Schwarz strain	5,067	100%	T2	0%	304
primaquine phosphate 26.3 MG Oral Tablet primaquine phosphate	5,067	100%	T3	0%	300
vemurafenib 240 MG Oral Tablet [Zelboraf] vemurafenib	5,067	100%	T4	99.4%	298
mesna 400 MG Oral Tablet mesna	5,067	100%	T4	0%	284
erdafitinib 3 MG Oral Tablet [Balversa] erdafitinib	5,067	100%	T4	99.1%	275
erdafitinib 4 MG Oral Tablet [Balversa] erdafitinib	5,067	100%	T4	99.1%	275
erdafitinib 5 MG Oral Tablet [Balversa] erdafitinib	5,067	100%	T4	99.1%	275
chlorambucil 2 MG Oral Tablet [Leukeran] chlorambucil	5,067	100%	T4	22.1%	268
avapritinib 100 MG Oral Tablet [Ayvakit] avapritinib	5,067	100%	T4	99.4%	267
avapritinib 200 MG Oral Tablet [Ayvakit] avapritinib	5,067	100%	T4	99.4%	267
avapritinib 25 MG Oral Tablet [Ayvakit] avapritinib	5,067	100%	T4	99.4%	267
avapritinib 300 MG Oral Tablet [Ayvakit] avapritinib	5,067	100%	T4	99.4%	267
avapritinib 50 MG Oral Tablet [Ayvakit] avapritinib	5,067	100%	T4	99.4%	267
lapatinib 250 MG Oral Tablet lapatinib	5,067	100%	T4	99.4%	260
1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injection [RabAvert] rabies virus vaccine flury-lep strain	5,067	100%	T2	90.9%	259
ripretinib 50 MG Oral Tablet [Qinlock] ripretinib	5,067	100%	T4	99.4%	255
tepotinib 225 MG Oral Tablet [Tepmetko] tepotinib	5,067	100%	T4	99.4%	249
pegvisomant 10 MG Injection [Somavert] pegvisomant	5,067	100%	T4	97%	247
pegvisomant 15 MG Injection [Somavert] pegvisomant	5,067	100%	T4	97%	247
pegvisomant 20 MG Injection [Somavert] pegvisomant	5,067	100%	T4	97%	247
brigatinib 90 MG Oral Tablet [Alunbrig] brigatinib	5,067	100%	T4	99.4%	237
brigatinib 30 MG Oral Tablet [Alunbrig] brigatinib	5,067	100%	T4	99.4%	237
brigatinib 180 MG Oral Tablet [Alunbrig] brigatinib	5,067	100%	T4	99.4%	237
{23 (brigatinib 180 MG Oral Tablet [Alunbrig]) / 7 (brigatinib 90 MG Oral Tablet [Alunbrig]) } Pack [Alunbrig Initiation Pack] brigatinib	5,067	100%	T4	99.4%	237
talazoparib 0.1 MG Oral Capsule [Talzenna] talazoparib	5,067	100%	T4	99.4%	234
talazoparib 0.25 MG Oral Capsule [Talzenna] talazoparib	5,067	100%	T4	99.4%	234
talazoparib 0.35 MG Oral Capsule [Talzenna] talazoparib	5,067	100%	T4	99.4%	234
talazoparib 0.5 MG Oral Capsule [Talzenna] talazoparib	5,067	100%	T4	99.4%	234
talazoparib 0.75 MG Oral Capsule [Talzenna] talazoparib	5,067	100%	T4	99.4%	234

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team