Medicare Part D drugs starting with U
11 drugs start with U; 1 of them are on at least 90% of 2026 Part D formularies. Part D spending was highest for Uptravi in 2024: $909 million, what plans and patients paid at the pharmacy before rebates.
Which drugs start with U?
| Drug | Plans covering | Usual tier | Medicare spending, 2024 |
|---|---|---|---|
| Ubrelvy (ubrogepant) | 80.4% | Tier 3 | $430 million |
| Udenyca (pegfilgrastim-cbqv) | 42.2% | Tier 5 | $20 million |
| Umeclidinium / vilanterol | 6.4% | Tier 3 | no 2024 match |
| Unithroid (levothyroxine sodium) | 89.2% | Tier 1 | $4 million |
| Uptravi (selexipag) | 62% | Tier 5 | $909 million |
| Ursodiol | 100% | Tier 3 | $78 million |
| Ustekinumab | 72.7% | Tier 5 | no 2024 match |
| Ustekinumab-aauz | 3.1% | Tier 3 | no 2024 match |
| Ustekinumab-aekn | 17.3% | Tier 4 | no 2024 match |
| Ustekinumab-ttwe | 6.7% | Tier 3 | no 2024 match |
| Uzedy (risperidone) | 9.2% | Tier 5 | $65 million |
Source: CMS Part D formulary file, 2026 second quarter; CMS Medicare Part D Spending by Drug, 2024.
What else should you check?
- Every drug, by letterAnd the 20 that cost Medicare most
- Stand-alone drug plans for 2027Premiums and deductibles
- Part D in 2027What changes for drug plans