Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.
Drug Name Plans Covering Coverage % Avg Tier PA % 2023 Benes
{14 (24 HR apremilast 75 MG Extended Release Oral Tablet [Otezla]) / 4 (apremilast 10 MG Oral Tablet [Otezla]) / 4 (apremilast 20 MG Oral Tablet [Otezla]) / 19 (apremilast 30 MG Oral Tablet [Otezla]) } Pack [Otezla 28-Day 10/20/30/75 Starter Pack]
apremilast
2,625 51.8% T4 100% 26,811
loteprednol etabonate 0.005 MG/MG Ophthalmic Ointment [Lotemax]
loteprednol etabonate
2,623 51.8% T3 0% 91,483
0.25 ML somatropin 0.8 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T3 100% 1,572
0.25 ML somatropin 1.6 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 2.4 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 3.2 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 4 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 4.8 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 5.6 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 6.4 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 7.2 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
0.25 ML somatropin 8 MG/ML Prefilled Syringe [Genotropin]
somatropin
2,619 51.7% T4 100% 1,572
azilsartan medoxomil 40 MG Oral Tablet [Edarbi]
azilsartan medoxomil
2,618 51.7% T3 0% 17,111
azilsartan medoxomil 80 MG Oral Tablet [Edarbi]
azilsartan medoxomil
2,618 51.7% T3 0% 17,111
avatrombopag 20 MG Oral Tablet [Doptelet]
avatrombopag
2,610 51.5% T4 99.5% 1,609
1 ML epoetin alfa-epbx 40000 UNT/ML Injection [Retacrit]
epoetin alfa-epbx
2,608 51.5% T3 99.2% 12,187
{10 (avatrombopag 20 MG Oral Tablet [Doptelet]) } Pack [Doptelet 40 MG Daily Dose Carton]
avatrombopag
2,604 51.4% T4 99.5% 1,609
{15 (avatrombopag 20 MG Oral Tablet [Doptelet]) } Pack [Doptelet 60 MG Daily Dose Carton]
avatrombopag
2,604 51.4% T4 99.5% 1,609
nafarelin 0.2 MG/ACTUAT Metered Dose Nasal Spray [Synarel]
nafarelin
2,604 51.4% T4 50.8% 15
1250 MG testosterone 0.0162 MG/MG Topical Gel
testosterone
2,601 51.3% T3 85.1% -
2500 MG testosterone 0.0162 MG/MG Topical Gel
testosterone
2,596 51.2% T3 85.1% -
bacitracin zinc 0.4 UNT/MG / hydrocortisone acetate 0.01 MG/MG / neomycin sulfate 0.0035 MG/MG / polymyxin B sulfate 10 UNT/MG Ophthalmic Ointment [Neo-Polycin HC]
bacitracin zinc
2,575 50.8% T2 0% 14,794
pyridostigmine bromide 180 MG Extended Release Oral Tablet
pyridostigmine bromide
2,546 50.2% T3 0% 56,300
dextroamphetamine sulfate 5 MG Extended Release Oral Capsule
dextroamphetamine sulfate
2,541 50.1% T3 0.9% 9,950
dextroamphetamine sulfate 10 MG Extended Release Oral Capsule
dextroamphetamine sulfate
2,541 50.1% T3 0.9% 9,950
dextroamphetamine sulfate 15 MG Extended Release Oral Capsule
dextroamphetamine sulfate
2,541 50.1% T3 0.9% 9,950
tadalafil 2.5 MG Oral Tablet
tadalafil
2,531 50% T3 100% 74,638
tazarotene 0.5 MG/ML Topical Cream
tazarotene
2,515 49.6% T3 81.2% 4,869
nepafenac 3 MG/ML Ophthalmic Suspension [Ilevro]
nepafenac
2,492 49.2% T3 0% 28,476
glipizide 2.5 MG Oral Tablet
glipizide
2,488 49.1% T3 0% 1,178,840
loteprednol etabonate 2.5 MG/ML Ophthalmic Suspension [Eysuvis]
loteprednol etabonate
2,483 49% T3 15% 91,483
nalmefene 27 MG/ML Nasal Spray [Opvee]
nalmefene
2,478 48.9% T3 0% -
1 ML mepolizumab 100 MG/ML Auto-Injector [Nucala]
mepolizumab
2,477 48.9% T4 100% 7,618
1 ML mepolizumab 100 MG/ML Prefilled Syringe [Nucala]
mepolizumab
2,477 48.9% T4 100% 7,618
omadacycline 150 MG Oral Tablet [Nuzyra]
omadacycline
2,470 48.7% T4 8.6% 3,687
nystatin 100000 UNT/ML / triamcinolone acetonide 1 MG/ML Topical Cream
nystatin
2,469 48.7% T2 0% 1,571,473
cevimeline hydrochloride 30 MG Oral Capsule
cevimeline hydrochloride
2,467 48.7% T3 0% 26,123
0.5 ML filgrastim-aafi 0.6 MG/ML Prefilled Syringe [Nivestym]
filgrastim-aafi
2,459 48.5% T4 76.7% -
0.8 ML filgrastim-aafi 0.6 MG/ML Prefilled Syringe [Nivestym]
filgrastim-aafi
2,459 48.5% T4 76.7% -
hydrocortisone valerate 0.002 MG/MG Topical Ointment
hydrocortisone valerate
2,455 48.5% T3 0% 15,376
0.4 ML mepolizumab 100 MG/ML Prefilled Syringe [Nucala]
mepolizumab
2,455 48.5% T4 100% 7,618
epinastine hydrochloride 0.5 MG/ML Ophthalmic Solution
epinastine hydrochloride
2,454 48.4% T2 0% 7,817
1 ML filgrastim-aafi 0.3 MG/ML Injection [Nivestym]
filgrastim-aafi
2,447 48.3% T4 76.6% -
1.6 ML filgrastim-aafi 0.3 MG/ML Injection [Nivestym]
filgrastim-aafi
2,447 48.3% T4 76.6% -
doxepin 3 MG Oral Tablet
doxepin
2,446 48.3% T2 1.6% 276,316
doxepin 6 MG Oral Tablet
doxepin
2,446 48.3% T2 1.6% 276,316
olanzapine 5 MG / samidorphan 10 MG Oral Tablet [Lybalvi]
olanzapine
2,442 48.2% T4 43.9% 516,737
olanzapine 10 MG / samidorphan 10 MG Oral Tablet [Lybalvi]
olanzapine
2,442 48.2% T4 43.9% 516,737
olanzapine 15 MG / samidorphan 10 MG Oral Tablet [Lybalvi]
olanzapine
2,442 48.2% T4 43.9% 516,737
olanzapine 20 MG / samidorphan 10 MG Oral Tablet [Lybalvi]
olanzapine
2,442 48.2% T4 43.9% 516,737
tretinoin 0.0005 MG/MG Topical Gel
tretinoin
2,437 48.1% T3 90.6% 91,688
pentosan polysulfate 100 MG Oral Capsule [Elmiron]
pentosan polysulfate
2,434 48% T3 2.7% 593,832
nystatin 100 UNT/MG / triamcinolone acetonide 0.001 MG/MG Topical Ointment
nystatin
2,430 48% T2 0% 1,571,473
levocetirizine dihydrochloride 0.5 MG/ML Oral Solution
levocetirizine dihydrochloride
2,427 47.9% T3 0% 642,854
fidaxomicin 40 MG/ML Oral Suspension [Dificid]
fidaxomicin
2,427 47.9% T4 19.6% 21,562
hydrocortisone butyrate 0.001 MG/MG Topical Ointment
hydrocortisone butyrate
2,426 47.9% T3 0% 6,139
lidocaine 0.05 MG/MG Medicated Patch [Lidocan]
lidocaine
2,422 47.8% T3 95.2% 481,042
0.4 ML adalimumab-bwwd 100 MG/ML Prefilled Syringe [Hadlima]
adalimumab-bwwd
2,418 47.7% T4 98.5% -
0.4 ML adalimumab-bwwd 100 MG/ML Auto-Injector [Hadlima]
adalimumab-bwwd
2,418 47.7% T4 98.5% -
0.8 ML adalimumab-bwwd 50 MG/ML Prefilled Syringe [Hadlima]
adalimumab-bwwd
2,414 47.6% T4 98.5% -
0.8 ML adalimumab-bwwd 50 MG/ML Auto-Injector [Hadlima]
adalimumab-bwwd
2,414 47.6% T4 98.5% -
glimepiride 2 MG / pioglitazone 30 MG Oral Tablet
glimepiride
2,411 47.6% T3 0% 1,187,344
glimepiride 4 MG / pioglitazone 30 MG Oral Tablet
glimepiride
2,411 47.6% T3 0% 1,187,344
teduglutide 5 MG Injection [Gattex]
teduglutide
2,408 47.5% T4 100% 914
estrogens, conjugated (USP) 0.3 MG Oral Tablet
estrogens,
2,391 47.2% T2 4.9% 241,518
estrogens, conjugated (USP) 0.45 MG Oral Tablet
estrogens,
2,391 47.2% T2 4.9% 241,518
estrogens, conjugated (USP) 0.625 MG Oral Tablet
estrogens,
2,391 47.2% T2 4.9% 241,518
estrogens, conjugated (USP) 0.9 MG Oral Tablet
estrogens,
2,391 47.2% T2 4.9% 241,518
estrogens, conjugated (USP) 1.25 MG Oral Tablet
estrogens,
2,391 47.2% T2 4.9% 241,518
loteprednol etabonate 5 MG/ML Ophthalmic Suspension
loteprednol etabonate
2,389 47.1% T2 0% 91,483
ketorolac tromethamine 10 MG Oral Tablet
ketorolac tromethamine
2,369 46.8% T2 31.1% 951,621
desonide 0.5 MG/ML Topical Cream
desonide
2,359 46.6% T3 0% 101,247
omadacycline 100 MG Injection [Nuzyra]
omadacycline
2,350 46.4% T4 15% 3,687
{24 (ethinyl estradiol 0.02 MG / norethindrone acetate 1 MG Chewable Tablet) / 4 (ferrous fumarate 75 MG Oral Tablet) } Pack
ethinyl estradiol
2,340 46.2% T2 0% -
triptorelin 11.25 MG Injection [Trelstar]
triptorelin
2,338 46.1% T3 80.4% 2,074
lisdexamfetamine dimesylate 10 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 20 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 30 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 40 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 50 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 60 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
lisdexamfetamine dimesylate 70 MG Oral Capsule
lisdexamfetamine dimesylate
2,329 46% T3 15% 57,529
{24 (ethinyl estradiol 0.025 MG / norethindrone 0.8 MG Chewable Tablet) / 4 (ferrous fumarate 75 MG Chewable Tablet) } Pack [Kaitlib Fe 28 Day]
ethinyl estradiol
2,322 45.8% T2 0% -
adapalene 0.003 MG/MG Topical Gel
adapalene
2,320 45.8% T3 29.7% 4,155
oxycodone hydrochloride 5 MG Oral Capsule
oxycodone hydrochloride
2,307 45.5% T2 2.5% 2,133,988
{56 (amoxicillin 500 MG Oral Capsule) / 28 (clarithromycin 500 MG Oral Tablet) / 28 (vonoprazan 20 MG Oral Tablet) } Pack [Voquezna 14 Day TriplePak 20;500;500]
amoxicillin
2,307 45.5% T3 91.9% -
Hyponatremia tolvaptan 15 MG Oral Tablet
Hyponatremia tolvaptan
2,306 45.5% T4 92.1% -
loteprednol etabonate 0.005 MG/MG Ophthalmic Gel
loteprednol etabonate
2,303 45.5% T2 0% 91,483
Hyponatremia tolvaptan 30 MG Oral Tablet
Hyponatremia tolvaptan
2,302 45.4% T4 92.8% -
fluoxetine 90 MG Delayed Release Oral Capsule
fluoxetine
2,301 45.4% T3 0% 1,427,221
phenytoin sodium 100 MG Extended Release Oral Capsule [Dilantin]
phenytoin sodium
2,299 45.4% T3 8% 11
{84 (amoxicillin 500 MG Oral Capsule) / 28 (vonoprazan 20 MG Oral Tablet) } Pack [Voquezna 14 Day DualPak 20;500]
amoxicillin
2,299 45.4% T3 93.6% -
erythromycin lactobionate 500 MG Injection [Erythrocin]
erythromycin lactobionate
2,299 45.4% T3 1.4% -
lidocaine 0.05 MG/MG Medicated Patch [Tridacaine]
lidocaine
2,298 45.4% T3 95% 481,042
mupirocin 20 MG/ML Topical Cream
mupirocin
2,297 45.3% T3 0% 2,467,308
promethazine hydrochloride 25 MG Rectal Suppository
promethazine hydrochloride
2,296 45.3% T3 43.8% 523,738
fluoxetine 20 MG Oral Tablet
fluoxetine
2,292 45.2% T2 0% 1,427,221
triptorelin 22.5 MG Injection [Trelstar]
triptorelin
2,288 45.2% T3 80.4% 2,074
demeclocycline hydrochloride 150 MG Oral Tablet
demeclocycline hydrochloride
2,283 45.1% T3 0.6% 2,089
demeclocycline hydrochloride 300 MG Oral Tablet
demeclocycline hydrochloride
2,283 45.1% T3 0.6% 2,089
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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.