Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
hydrochlorothiazide 12.5 MG / valsartan 160 MG Oral Tablet hydrochlorothiazide	5,065	100%	T2	0%	4,902,174
hydrochlorothiazide 25 MG / valsartan 160 MG Oral Tablet hydrochlorothiazide	5,065	100%	T2	0%	4,902,174
hydrochlorothiazide 12.5 MG / valsartan 320 MG Oral Tablet hydrochlorothiazide	5,065	100%	T2	0%	4,902,174
hydrochlorothiazide 25 MG / valsartan 320 MG Oral Tablet hydrochlorothiazide	5,065	100%	T2	0%	4,902,174
simvastatin 80 MG Oral Tablet simvastatin	5,065	100%	T2	1.5%	3,917,152
buspirone hydrochloride 7.5 MG Oral Tablet buspirone hydrochloride	5,065	100%	T2	0%	1,420,432
hydrocortisone 25 MG/ML Topical Cream hydrocortisone	5,065	100%	T2	0%	1,257,661
fenofibrate 54 MG Oral Tablet fenofibrate	5,065	100%	T2	0%	500,170
bisoprolol fumarate 5 MG Oral Tablet bisoprolol fumarate	5,065	100%	T2	0%	262,683
bisoprolol fumarate 10 MG Oral Tablet bisoprolol fumarate	5,065	100%	T2	0%	262,683
minocycline 75 MG Oral Capsule minocycline	5,065	100%	T2	0%	158,316
sodium polystyrene sulfonate 15000 MG Powder for Oral Suspension sodium polystyrene sulfonate	5,065	100%	T2	0%	29,272
clindamycin 10 MG/ML Topical Solution clindamycin	5,065	100%	T2	0%	8,722
ceftriaxone 100 MG/ML Injectable Solution ceftriaxone	5,065	100%	T3	0%	3,930
Atrial Fibrillation sotalol hydrochloride 120 MG Oral Tablet Atrial Fibrillation sotalol hydrochloride	5,065	100%	T2	0%	-
{11 (varenicline 0.5 MG Oral Tablet) / 42 (varenicline 1 MG Oral Tablet) } Pack varenicline	5,065	100%	T3	0%	-
Augmented betamethasone 0.5 MG/ML Topical Cream Augmented betamethasone	5,065	100%	T2	0%	-
polyethylene glycol 3350 420000 MG / potassium chloride 1480 MG / sodium bicarbonate 5720 MG / sodium chloride 11200 MG Powder for Oral Solution polyethylene glycol	5,065	100%	T2	0%	-
triamcinolone acetonide 1 MG/ML Topical Lotion triamcinolone acetonide	5,063	99.9%	T2	0%	3,621,019
triamcinolone acetonide 1 MG/ML Topical Cream triamcinolone acetonide	5,063	99.9%	T2	0%	3,621,019
triamcinolone acetonide 5 MG/ML Topical Cream triamcinolone acetonide	5,063	99.9%	T2	0%	3,621,019
dexamethasone phosphate 1 MG/ML Ophthalmic Solution dexamethasone phosphate	5,063	99.9%	T2	0%	850,184
lactulose 667 MG/ML Oral Solution [Enulose] lactulose	5,063	99.9%	T2	0%	526,962
ammonium lactate 120 MG/ML Topical Cream ammonium lactate	5,063	99.9%	T2	0.3%	491,025
cholestyramine resin 4000 MG Powder for Oral Suspension cholestyramine resin	5,063	99.9%	T2	0%	186,287
modafinil 100 MG Oral Tablet modafinil	5,063	99.9%	T2	96.7%	69,010
modafinil 200 MG Oral Tablet modafinil	5,063	99.9%	T2	96.7%	69,010
misoprostol 0.1 MG Oral Tablet misoprostol	5,063	99.9%	T2	0%	47,809
theophylline 600 MG Extended Release Oral Tablet theophylline	5,063	99.9%	T2	0%	39,063
theophylline 400 MG Extended Release Oral Tablet theophylline	5,063	99.9%	T2	0%	39,063
leucovorin 10 MG Oral Tablet leucovorin	5,063	99.9%	T2	0%	26,004
voriconazole 50 MG Oral Tablet voriconazole	5,063	99.9%	T3	43.2%	11,795
ceftazidime 200 MG/ML Injectable Solution ceftazidime	5,063	99.9%	T3	8.5%	5,212
ceftazidime 1000 MG Injection ceftazidime	5,063	99.9%	T3	8.5%	5,212
100 ML fluconazole 2 MG/ML Injection fluconazole	5,063	99.9%	T3	12.5%	-
100 ML levofloxacin 5 MG/ML Injection levofloxacin	5,063	99.9%	T3	8.2%	-
bedaquiline 20 MG Oral Tablet [Sirturo] bedaquiline	5,063	99.9%	T4	75.7%	-
chlorpromazine hydrochloride 100 MG/ML Oral Solution chlorpromazine hydrochloride	5,062	99.9%	T3	15.5%	37,336
72 HR fentanyl 0.012 MG/HR Transdermal System fentanyl	5,062	99.9%	T3	49.8%	-
triamcinolone acetonide 0.001 MG/MG Oral Paste triamcinolone acetonide	5,061	99.9%	T2	0%	3,621,019
sulfamethoxazole 40 MG/ML / trimethoprim 8 MG/ML Oral Suspension sulfamethoxazole	5,061	99.9%	T2	0%	3,086,523
metronidazole 0.0075 MG/MG Topical Gel metronidazole	5,061	99.9%	T2	0%	1,528,785
betamethasone 1 MG/ML Topical Cream betamethasone	5,061	99.9%	T2	0%	407,711
betamethasone 0.001 MG/MG Topical Ointment betamethasone	5,061	99.9%	T2	0%	407,711
lithium carbonate 300 MG Oral Tablet lithium carbonate	5,061	99.9%	T1	0%	103,265
tretinoin 0.25 MG/ML Topical Cream tretinoin	5,061	99.9%	T3	92.4%	91,688
3 ML insulin, regular, human 100 UNT/ML Pen Injector [Novolin R] insulin, regular, human	5,061	99.9%	T3	0%	32,117
isavuconazonium sulfate 74.5 MG Oral Capsule [Cresemba] isavuconazonium sulfate	5,061	99.9%	T4	91.7%	3,570
octreotide 0.2 MG/ML Injectable Solution octreotide	5,061	99.9%	T3	75.4%	3,041
1 ML octreotide 0.05 MG/ML Injection octreotide	5,061	99.9%	T3	75.1%	-
24 HR oxybutynin chloride 15 MG Extended Release Oral Tablet oxybutynin chloride	5,061	99.9%	T2	0.6%	-
Atrial Fibrillation sotalol hydrochloride 80 MG Oral Tablet Atrial Fibrillation sotalol hydrochloride	5,061	99.9%	T2	0%	-
12 HR timolol 5 MG/ML Ophthalmic Solution timolol	5,061	99.9%	T1	0%	-
24 HR oxybutynin chloride 5 MG Extended Release Oral Tablet oxybutynin chloride	5,061	99.9%	T2	0.6%	-
24 HR oxybutynin chloride 10 MG Extended Release Oral Tablet oxybutynin chloride	5,061	99.9%	T2	0.6%	-
Atrial Fibrillation sotalol hydrochloride 160 MG Oral Tablet Atrial Fibrillation sotalol hydrochloride	5,061	99.9%	T2	0%	-
morphine sulfate 100 MG Extended Release Oral Tablet morphine sulfate	5,060	99.9%	T2	49.8%	255,247
buprenorphine 2 MG / naloxone 0.5 MG Sublingual Tablet buprenorphine	5,060	99.9%	T2	0%	74,893
buprenorphine 8 MG / naloxone 2 MG Sublingual Tablet buprenorphine	5,060	99.9%	T2	0%	74,893
propafenone hydrochloride 300 MG Oral Tablet propafenone hydrochloride	5,060	99.9%	T2	0%	51,674
fluconazole 10 MG/ML Oral Suspension fluconazole	5,059	99.8%	T2	0%	2,001,592
atenolol 50 MG / chlorthalidone 25 MG Oral Tablet atenolol	5,059	99.8%	T1	0%	1,630,835
atenolol 100 MG / chlorthalidone 25 MG Oral Tablet atenolol	5,059	99.8%	T1	0%	1,630,835
glipizide 2.5 MG / metformin hydrochloride 250 MG Oral Tablet glipizide	5,059	99.8%	T2	0%	1,178,840
glipizide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet glipizide	5,059	99.8%	T2	0%	1,178,840
glipizide 5 MG / metformin hydrochloride 500 MG Oral Tablet glipizide	5,059	99.8%	T2	0%	1,178,840
lithium carbonate 600 MG Oral Capsule lithium carbonate	5,059	99.8%	T1	0%	103,265
indapamide 1.25 MG Oral Tablet indapamide	5,059	99.8%	T1	0%	97,501
indapamide 2.5 MG Oral Tablet indapamide	5,059	99.8%	T1	0%	97,501
amphetamine aspartate 1.875 MG / amphetamine sulfate 1.875 MG / dextroamphetamine saccharate 1.875 MG / dextroamphetamine sulfate 1.875 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
amphetamine aspartate 3.75 MG / amphetamine sulfate 3.75 MG / dextroamphetamine saccharate 3.75 MG / dextroamphetamine sulfate 3.75 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
amphetamine aspartate 1.25 MG / amphetamine sulfate 1.25 MG / dextroamphetamine saccharate 1.25 MG / dextroamphetamine sulfate 1.25 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
amphetamine aspartate 2.5 MG / amphetamine sulfate 2.5 MG / dextroamphetamine saccharate 2.5 MG / dextroamphetamine sulfate 2.5 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
amphetamine aspartate 5 MG / amphetamine sulfate 5 MG / dextroamphetamine saccharate 5 MG / dextroamphetamine sulfate 5 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
amphetamine aspartate 7.5 MG / amphetamine sulfate 7.5 MG / dextroamphetamine saccharate 7.5 MG / dextroamphetamine sulfate 7.5 MG Oral Tablet amphetamine aspartate	5,059	99.8%	T2	19.8%	466
{6 (nirmatrelvir 150 MG Oral Tablet) / 5 (ritonavir 100 MG Oral Tablet) } Pack [Paxlovid 300 MG /100 MG ; 150 MG / 100 MG Dose Pack] nirmatrelvir	5,059	99.8%	T2	0%	-
potassium chloride 1.33 MEQ/ML Oral Solution potassium chloride	5,058	99.8%	T3	0%	3,479,756
gentamicin 3 MG/ML Ophthalmic Solution gentamicin	5,058	99.8%	T2	0%	255,052
clarithromycin 25 MG/ML Oral Suspension clarithromycin	5,058	99.8%	T3	0%	168,843
clarithromycin 50 MG/ML Oral Suspension clarithromycin	5,058	99.8%	T3	0%	168,843
theophylline 300 MG Extended Release Oral Tablet theophylline	5,058	99.8%	T3	0%	39,063
meropenem 500 MG Injection meropenem	5,058	99.8%	T2	6.1%	27,599
bacitracin 0.5 UNT/MG / polymyxin B 10 UNT/MG Ophthalmic Ointment bacitracin	5,058	99.8%	T2	0%	14,794
12 HR bupropion hydrochloride 100 MG Extended Release Oral Tablet bupropion hydrochloride	5,058	99.8%	T2	0%	-
12 HR bupropion hydrochloride 150 MG Extended Release Oral Tablet bupropion hydrochloride	5,058	99.8%	T2	0%	-
12 HR bupropion hydrochloride 200 MG Extended Release Oral Tablet bupropion hydrochloride	5,058	99.8%	T2	0%	-
1 ML octreotide 0.1 MG/ML Injection octreotide	5,058	99.8%	T3	75.4%	-
doxycycline hyclate 100 MG Oral Capsule doxycycline hyclate	5,057	99.8%	T2	0%	4,121,486
doxycycline hyclate 100 MG Oral Tablet doxycycline hyclate	5,057	99.8%	T2	0%	4,121,486
doxycycline hyclate 20 MG Oral Tablet doxycycline hyclate	5,057	99.8%	T2	0%	4,121,486
oxycodone hydrochloride 5 MG Oral Tablet oxycodone hydrochloride	5,057	99.8%	T2	0.9%	2,133,988
oxycodone hydrochloride 15 MG Oral Tablet oxycodone hydrochloride	5,057	99.8%	T2	0.9%	2,133,988
oxycodone hydrochloride 30 MG Oral Tablet oxycodone hydrochloride	5,057	99.8%	T2	1.2%	2,133,988
oxycodone hydrochloride 10 MG Oral Tablet oxycodone hydrochloride	5,057	99.8%	T2	0.9%	2,133,988
oxycodone hydrochloride 20 MG Oral Tablet oxycodone hydrochloride	5,057	99.8%	T2	0.9%	2,133,988
promethazine hydrochloride 25 MG Oral Tablet promethazine hydrochloride	5,057	99.8%	T2	60.7%	523,738
lidocaine 25 MG/ML / prilocaine 25 MG/ML Topical Cream lidocaine	5,057	99.8%	T2	56.4%	481,042
betamethasone 1 MG/ML Topical Lotion betamethasone	5,057	99.8%	T2	0%	407,711
budesonide 0.125 MG/ML Inhalation Suspension budesonide	5,057	99.8%	T3	99.7%	61,841
meropenem 1000 MG Injection meropenem	5,057	99.8%	T3	6.1%	27,599

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team