Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
piperacillin 2000 MG / tazobactam 250 MG Injection piperacillin	5,057	99.8%	T3	0%	22,422
norethindrone acetate 5 MG Oral Tablet norethindrone acetate	5,057	99.8%	T2	0%	15,646
ceftriaxone 1000 MG Injection ceftriaxone	5,057	99.8%	T3	0%	3,930
ceftriaxone 2000 MG Injection ceftriaxone	5,057	99.8%	T3	0%	3,930
lomustine 10 MG Oral Capsule lomustine	5,057	99.8%	T3	12.8%	662
lomustine 40 MG Oral Capsule lomustine	5,057	99.8%	T4	12.8%	662
lomustine 100 MG Oral Capsule lomustine	5,057	99.8%	T4	12.8%	662
{2 (sotatercept-csrk 45 MG Injection [Winrevair]) } Pack [Winrevair 45 MG, 2 Vial Kit] sotatercept-csrk	5,057	99.8%	T4	99.4%	-
12 HR carbamazepine 100 MG Extended Release Oral Capsule carbamazepine	5,057	99.8%	T3	0%	-
12 HR carbamazepine 200 MG Extended Release Oral Capsule carbamazepine	5,057	99.8%	T3	0%	-
12 HR carbamazepine 300 MG Extended Release Oral Capsule carbamazepine	5,057	99.8%	T3	0%	-
100 ML sodium chloride 9 MG/ML Injection sodium chloride	5,057	99.8%	T3	1.2%	-
{2 (sotatercept-csrk 60 MG Injection [Winrevair]) } Pack [Winrevair 60 MG, 2 Vial Kit] sotatercept-csrk	5,056	99.8%	T4	99.4%	-
amoxicillin 500 MG Oral Tablet amoxicillin	5,055	99.8%	T1	0%	6,202,496
griseofulvin 25 MG/ML Oral Suspension griseofulvin	5,055	99.8%	T3	0%	1,743
72 HR fentanyl 0.1 MG/HR Transdermal System fentanyl	5,055	99.8%	T3	52.3%	-
Microencapsulated potassium chloride 10 MEQ Extended Release Oral Tablet Microencapsulated potassium chloride	5,055	99.8%	T2	0%	-
Microencapsulated potassium chloride 20 MEQ Extended Release Oral Tablet Microencapsulated potassium chloride	5,055	99.8%	T2	0%	-
Sprinkle duloxetine 40 MG Delayed Release Oral Capsule [Drizalma] Sprinkle duloxetine	5,055	99.8%	T3	35.9%	-
ciclopirox 7.7 MG/ML Topical Cream ciclopirox	5,054	99.7%	T2	0%	397,306
24 HR diltiazem hydrochloride 120 MG Extended Release Oral Capsule [Dilt] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 180 MG Extended Release Oral Capsule [Dilt] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 240 MG Extended Release Oral Capsule [Dilt] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 120 MG Extended Release Oral Capsule [Cartia] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 180 MG Extended Release Oral Capsule [Cartia] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 240 MG Extended Release Oral Capsule [Cartia] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
24 HR diltiazem hydrochloride 300 MG Extended Release Oral Capsule [Cartia] diltiazem hydrochloride	5,054	99.7%	T2	0%	-
hydromorphone hydrochloride 2 MG Oral Tablet hydromorphone hydrochloride	5,053	99.7%	T2	0.9%	234,154
hydromorphone hydrochloride 4 MG Oral Tablet hydromorphone hydrochloride	5,053	99.7%	T2	0.9%	234,154
hydromorphone hydrochloride 8 MG Oral Tablet hydromorphone hydrochloride	5,053	99.7%	T2	0.9%	234,154
roflumilast 0.25 MG Oral Tablet roflumilast	5,053	99.7%	T3	29.6%	59,491
clindamycin 75 MG Oral Capsule clindamycin	5,053	99.7%	T2	0%	8,722
polyethylene glycol 3350 240000 MG / potassium chloride 2980 MG / sodium bicarbonate 6720 MG / sodium chloride 5840 MG / sodium sulfate 22720 MG Powder for Oral Solution [GaviLyte-C] polyethylene glycol	5,052	99.7%	T2	0%	338,109
selenium sulfide 25 MG/ML Medicated Shampoo selenium sulfide	5,052	99.7%	T2	0%	24,476
cefazolin 500 MG Injection cefazolin	5,052	99.7%	T3	0%	19,643
bacitracin 0.4 UNT/MG / neomycin 0.0035 MG/MG / polymyxin B 10 UNT/MG Ophthalmic Ointment bacitracin	5,052	99.7%	T2	0%	14,794
tinidazole 250 MG Oral Tablet tinidazole	5,052	99.7%	T3	0%	6,633
flucytosine 250 MG Oral Capsule flucytosine	5,052	99.7%	T4	39.9%	2,899
danazol 50 MG Oral Capsule danazol	5,052	99.7%	T3	13.7%	1,840
danazol 200 MG Oral Capsule danazol	5,052	99.7%	T3	13.7%	1,840
cefepime 1000 MG Injection cefepime	5,052	99.7%	T3	0%	1,061
dornase alfa 1 MG/ML Inhalation Solution [Pulmozyme] dornase alfa	5,052	99.7%	T4	100%	87
lithium citrate 60 MG/ML Oral Solution lithium citrate	5,052	99.7%	T2	0.3%	19
1.14 ML dupilumab 175 MG/ML Prefilled Syringe [Dupixent] dupilumab	5,052	99.7%	T4	100%	-
1 ML medroxyprogesterone acetate 150 MG/ML Prefilled Syringe medroxyprogesterone acetate	5,052	99.7%	T2	0%	-
{28 (norethindrone 0.35 MG Oral Tablet) } Pack norethindrone	5,052	99.7%	T2	0%	-
trientine hydrochloride 250 MG Oral Capsule trientine hydrochloride	5,052	99.7%	T4	87.2%	-
tramadol hydrochloride 50 MG Oral Tablet tramadol hydrochloride	5,051	99.7%	T2	0.9%	3,884,717
liothyronine sodium 0.005 MG Oral Tablet liothyronine sodium	5,051	99.7%	T2	0%	171,270
liothyronine sodium 0.025 MG Oral Tablet liothyronine sodium	5,051	99.7%	T2	0%	171,270
liothyronine sodium 0.05 MG Oral Tablet liothyronine sodium	5,051	99.7%	T2	0%	171,270
vancomycin 500 MG Injection vancomycin	5,051	99.7%	T3	0%	161,077
100 ML glucose 50 MG/ML Injection glucose	5,051	99.7%	T2	0.9%	-
tobramycin 60 MG/ML Inhalation Solution tobramycin	5,050	99.7%	T4	99.7%	195,319
albuterol 5 MG/ML Inhalation Solution albuterol	5,050	99.7%	T2	99.7%	1,487
penicillamine 250 MG Oral Tablet penicillamine	5,050	99.7%	T4	30%	162
1.14 ML dupilumab 175 MG/ML Auto-Injector [Dupixent] dupilumab	5,050	99.7%	T4	100%	-
2 ML naloxone hydrochloride 1 MG/ML Prefilled Syringe naloxone hydrochloride	5,050	99.7%	T2	0%	-
piperacillin 3000 MG / tazobactam 375 MG Injection piperacillin	5,049	99.6%	T3	0%	22,422
timolol 10 MG Oral Tablet timolol	5,049	99.6%	T3	0%	6,978
10 ML magnesium sulfate 500 MG/ML Prefilled Syringe magnesium sulfate	5,049	99.6%	T3	1.2%	-
cyclobenzaprine hydrochloride 5 MG Oral Tablet cyclobenzaprine hydrochloride	5,048	99.6%	T2	53%	2,458,292
cyclobenzaprine hydrochloride 10 MG Oral Tablet cyclobenzaprine hydrochloride	5,048	99.6%	T2	53%	2,458,292
prednisolone sodium phosphate 2.5 MG/ML / sulfacetamide sodium 100 MG/ML Ophthalmic Solution prednisolone sodium phosphate	5,048	99.6%	T2	0%	21,651
sacubitril 24 MG / valsartan 26 MG Oral Tablet sacubitril	5,047	99.6%	T2	0%	663,587
sacubitril 49 MG / valsartan 51 MG Oral Tablet sacubitril	5,047	99.6%	T2	0%	663,587
sacubitril 97 MG / valsartan 103 MG Oral Tablet sacubitril	5,047	99.6%	T2	0%	663,587
cefepime 2000 MG Injection cefepime	5,047	99.6%	T3	0%	1,061
pirfenidone 801 MG Oral Tablet pirfenidone	5,046	99.6%	T4	99.7%	7,776
ampicillin 1000 MG Injection ampicillin	5,046	99.6%	T3	10.1%	3,864
cilastatin 250 MG / imipenem 250 MG Injection cilastatin	5,046	99.6%	T3	6.7%	-
ibuprofen 600 MG Oral Tablet [Ibu] ibuprofen	5,045	99.6%	T1	0%	3,444,665
promethazine hydrochloride 50 MG Oral Tablet promethazine hydrochloride	5,045	99.6%	T2	60.9%	523,738
erythromycin 20 MG/ML Topical Solution erythromycin	5,045	99.6%	T2	0%	1,861
1 ML peginterferon alfa-2a 0.18 MG/ML Injection [Pegasys] peginterferon	5,045	99.6%	T4	71%	24
metronidazole 7.5 MG/ML Topical Cream metronidazole	5,044	99.5%	T3	0%	1,528,785
voriconazole 40 MG/ML Oral Suspension voriconazole	5,044	99.5%	T4	78%	11,795
{6 (azithromycin 250 MG Oral Tablet) } Pack azithromycin	5,044	99.5%	T1	0%	-
Augmented betamethasone 0.5 MG/ML Topical Lotion Augmented betamethasone	5,044	99.5%	T3	0%	-
levofloxacin 25 MG/ML Oral Solution levofloxacin	5,043	99.5%	T3	0%	1,827,884
octreotide 1 MG/ML Injectable Solution octreotide	5,043	99.5%	T4	75.2%	3,041
methadone hydrochloride 5 MG Oral Tablet methadone hydrochloride	5,042	99.5%	T2	35%	68,081
methadone hydrochloride 10 MG Oral Tablet methadone hydrochloride	5,042	99.5%	T2	37.1%	68,081
haloperidol decanoate 50 MG/ML Injectable Solution haloperidol decanoate	5,042	99.5%	T3	14.2%	34,910
1 ML haloperidol decanoate 100 MG/ML Injection haloperidol decanoate	5,042	99.5%	T3	14.2%	-
hydrochlorothiazide 25 MG / spironolactone 25 MG Oral Tablet hydrochlorothiazide	5,041	99.5%	T2	0%	4,902,174
diclofenac sodium 15 MG/ML Topical Solution diclofenac sodium	5,041	99.5%	T3	26.8%	3,196,668
celecoxib 400 MG Oral Capsule celecoxib	5,041	99.5%	T2	0%	1,627,703
nateglinide 60 MG Oral Tablet nateglinide	5,041	99.5%	T2	0%	38,358
nateglinide 120 MG Oral Tablet nateglinide	5,041	99.5%	T2	0%	38,358
1 ML naloxone hydrochloride 0.4 MG/ML Injection naloxone hydrochloride	5,041	99.5%	T2	0%	-
meclizine hydrochloride 25 MG Oral Tablet meclizine hydrochloride	5,040	99.5%	T2	20.5%	1,294,975
bosutinib 100 MG Oral Capsule [Bosulif] bosutinib	5,040	99.5%	T4	99.4%	1,732
{56 (varenicline 1 MG Oral Tablet) } Pack varenicline	5,040	99.5%	T3	0%	-
oseltamivir 6 MG/ML Oral Suspension oseltamivir	5,039	99.4%	T2	0%	380,069
vancomycin 100 MG/ML Injectable Solution vancomycin	5,039	99.4%	T3	0.6%	161,077
atropine sulfate 0.025 MG / diphenoxylate hydrochloride 2.5 MG Oral Tablet atropine sulfate	5,038	99.4%	T3	30.1%	109,532
0.5 ML omalizumab 150 MG/ML Auto-Injector [Xolair] omalizumab	5,038	99.4%	T4	100%	9,161
1 ML omalizumab 150 MG/ML Auto-Injector [Xolair] omalizumab	5,038	99.4%	T4	100%	9,161
2 ML omalizumab 150 MG/ML Prefilled Syringe [Xolair] omalizumab	5,038	99.4%	T4	100%	9,161

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team