Medicare Part D drugs starting with Y
12 drugs start with Y; 1 of them are on at least 90% of 2026 Part D formularies. Part D spending was highest for Yuvafem in 2024: $30 million, what plans and patients paid at the pharmacy before rebates.
Which drugs start with Y?
| Drug | Plans covering | Usual tier | Medicare spending, 2024 |
|---|---|---|---|
| Yargesa (miglustat) | 29.1% | Tier 5 | no 2024 match |
| Yasmin (drospirenone / ethinyl estradiol) | 0.1% | Tier 1 | $44 thousand |
| Yaz (drospirenone / ethinyl estradiol) | 0.1% | Tier 1 | $101 thousand |
| Yesintek (ustekinumab-kfce) | 74% | Tier 3 | no 2024 match |
| YF-Vax (yellow fever vaccine) | 100% | Tier 1 | $2 million |
| Yimmugo (immune globulin intravenous, human) | under 0.1% | Tier 2 | no 2024 match |
| Yonsa (abiraterone acetate) | 37.6% | Tier 5 | $15 million |
| Yorvipath (teriparatide) | 2.8% | Tier 5 | no 2024 match |
| Yuflyma (adalimumab-aaty) | 10.2% | Tier 5 | $9 million |
| Yupelri (revefenacin) | 9.9% | Tier 5 | $7 million |
| Yutrepia (treprostinil) | 15% | Tier 5 | no 2024 match |
| Yuvafem (estradiol) | 81.7% | Tier 4 | $30 million |
Source: CMS Part D formulary file, 2026 second quarter; CMS Medicare Part D Spending by Drug, 2024.
What else should you check?
- Every drug, by letterAnd the 20 that cost Medicare most
- Stand-alone drug plans for 2027Premiums and deductibles
- Part D in 2027What changes for drug plans