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Independent; not a government site. Official answers: Medicare.gov, 1-800-MEDICARE.

Is PremaSol (alanine and 18 more ingredients) covered by Medicare Part D?

4,241 of 5,052 Medicare Part D plan offerings (83.9%) list PremaSol on their 2026 formulary, most often on tier 5; 97.5% of the formularies that cover it require prior authorization.

Plans that cover it
83.9%
4,241 of 5,052 offerings; the median drug: 76%
Usual tier
Tier 5
from tier 1 to tier 6
Prior authorization
97.5%
of formularies that cover it; the median drug: 1%
Quantity limits
0%
of formularies that cover it; the median drug: 30%

Source: CMS Part D formulary file, 2026 second quarter: the formularies in use in 2026. A plan's 2027 formulary can differ; check your own plan's coverage in Medicare Plan Finder.

What does it cost under Part D in 2027?

Your yearly cap in 2027
Out-of-pocket spending on covered Part D drugs stops at $2,400 in 2027 ($2,100 in 2026); after that, you pay nothing for covered drugs for the rest of the year.
The deductible
A plan's drug deductible is at most $700 in 2027 ($615 in 2026); many plans charge less or none.

Source: CMS, Announcement of calendar year 2027 Part D parameters; Medicare.gov, “How much does Medicare drug coverage cost?” (read Oct. 7, 2026).

How much does Medicare spend on it?

Part D spending by year

2020$229 thousand
2021$194 thousand
2022$213 thousand
2023$547 thousand
2024 (latest)$418 thousand

Source: CMS Medicare Part D Spending by Drug, 2020 to 2024 (published June 2026). Row used: Premasol (Parenteral Amino Acid 10% No.7).

Which forms and strengths are counted?

  • alanine 5.4 mg/ml / arginine 12 mg/ml / aspartate 3.2 mg/ml / cysteine 0.16 mg/ml / glutamate 5 mg/ml / glycine 3.6 mg/ml / histidine 4.8 mg/ml / isoleucine 8.2 mg/ml / leucine 14 mg/ml / lysine 8.2 mg/ml / methionine 3.4 mg/ml / phenylalanine 4.8 mg/ml / proline 6.8 mg/ml / serine 3.8 mg/ml / taurine 0.25 mg/ml / threonine 4.2 mg/ml / tryptophan 2 mg/ml / tyrosine 2.4 mg/ml / valine 7.8 mg/ml injectable solution

What else should you check?

Data, not medical advice. Coverage is the share of plan formularies listing the drug; your plan's formulary, tier and pharmacy decide what you pay.