Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
24 HR donepezil hydrochloride 10 MG / memantine hydrochloride 28 MG Extended Release Oral Capsule [Namzaric] donepezil hydrochloride	1,240	24.5%	T3	6.9%	21,609
tolvaptan 15 MG Oral Tablet [Jynarque] tolvaptan	1,237	24.4%	T4	98.9%	1,228
tolvaptan 30 MG Oral Tablet [Jynarque] tolvaptan	1,237	24.4%	T4	98.9%	1,228
levonorgestrel 0.000833 MG/HR Intrauterine System [Mirena] levonorgestrel	1,214	24%	T3	3.3%	650
alanine 10.4 MG/ML / arginine 5.75 MG/ML / calcium chloride 0.004 MEQ/ML / dibasic potassium phosphate 2.61 MG/ML / glucose 150 MG/ML / glycine 5.15 MG/ML / histidine 2.4 MG/ML / isoleucine 3 MG/ML / leucine 3.65 MG/ML / lysine 2.9 MG/ML / magnesium chloride 0.01 MEQ/ML / methionine 2 MG/ML / phenylalanine 2.8 MG/ML / proline 3.4 MG/ML / serine 2.5 MG/ML / sodium acetate trihydrate 3.4 MG/ML / sodium chloride 0.01 MEQ/ML / threonine 2.1 MG/ML / tryptophan 0.9 MG/ML / tyrosine 0.2 MG/ML / valine 2.9 MG/ML Injectable Solution [Clinimix E 5/15] alanine	1,214	24%	T3	90.5%	-
alanine 5.7 MG/ML / arginine 3.16 MG/ML / calcium chloride 0.004 MEQ/ML / dibasic potassium phosphate 2.61 MG/ML / glucose 50 MG/ML / glycine 2.83 MG/ML / histidine 1.32 MG/ML / isoleucine 1.65 MG/ML / leucine 2.01 MG/ML / lysine 1.59 MG/ML / magnesium chloride 0.01 MEQ/ML / methionine 1.1 MG/ML / phenylalanine 1.54 MG/ML / proline 1.87 MG/ML / serine 1.38 MG/ML / sodium acetate trihydrate 2.17 MG/ML / sodium chloride 0.02 MEQ/ML / threonine 1.16 MG/ML / tryptophan 0.5 MG/ML / tyrosine 0.11 MG/ML / valine 1.6 MG/ML Injectable Solution [Clinimix E 2.75/5] alanine	1,214	24%	T3	90.5%	-
alanine 8.8 MG/ML / arginine 4.89 MG/ML / calcium chloride 0.004 MEQ/ML / dibasic potassium phosphate 2.61 MG/ML / glucose 50 MG/ML / glycine 4.38 MG/ML / histidine 2.04 MG/ML / isoleucine 2.55 MG/ML / leucine 3.11 MG/ML / lysine 2.47 MG/ML / magnesium chloride 0.01 MEQ/ML / methionine 1.7 MG/ML / phenylalanine 2.38 MG/ML / proline 2.89 MG/ML / serine 2.13 MG/ML / sodium acetate trihydrate 2.97 MG/ML / sodium chloride 0.013 MEQ/ML / threonine 1.79 MG/ML / tryptophan 0.77 MG/ML / tyrosine 0.17 MG/ML / valine 2.47 MG/ML Injectable Solution [Clinimix E 4.25/5] alanine	1,214	24%	T3	90.5%	-
alanine 10.4 MG/ML / arginine 5.75 MG/ML / calcium chloride 0.004 MEQ/ML / dibasic potassium phosphate 2.61 MG/ML / glucose 200 MG/ML / glycine 5.15 MG/ML / histidine 2.4 MG/ML / isoleucine 3 MG/ML / leucine 3.65 MG/ML / lysine 2.9 MG/ML / magnesium chloride 0.01 MEQ/ML / methionine 2 MG/ML / phenylalanine 2.8 MG/ML / proline 3.4 MG/ML / serine 2.5 MG/ML / sodium acetate trihydrate 3.4 MG/ML / sodium chloride 0.01 MEQ/ML / threonine 2.1 MG/ML / tryptophan 0.9 MG/ML / tyrosine 0.2 MG/ML / valine 2.9 MG/ML Injectable Solution [Clinimix E 5/20] alanine	1,214	24%	T3	90.5%	-
acetaminophen 300 MG / hydrocodone bitartrate 7.5 MG Oral Tablet acetaminophen	1,209	23.9%	T3	0%	156
acetaminophen 300 MG / hydrocodone bitartrate 10 MG Oral Tablet acetaminophen	1,209	23.9%	T3	0%	156
tretinoin 0.001 MG/MG Topical Gel tretinoin	1,207	23.8%	T4	81.8%	91,688
omaveloxolone 50 MG Oral Capsule [Skyclarys] omaveloxolone	1,207	23.8%	T5	98.1%	321
deutivacaftor 125 MG / tezacaftor 50 MG / vanzacaftor 10 MG Oral Tablet [Alyftrek] deutivacaftor	1,206	23.8%	T4	99.4%	-
deutivacaftor 50 MG / tezacaftor 20 MG / vanzacaftor 4 MG Oral Tablet [Alyftrek] deutivacaftor	1,206	23.8%	T4	99.4%	-
codeine sulfate 60 MG Oral Tablet codeine sulfate	1,205	23.8%	T3	0%	3,569
codeine sulfate 30 MG Oral Tablet codeine sulfate	1,201	23.7%	T3	0%	3,569
desonide 0.5 MG/ML Topical Lotion desonide	1,199	23.7%	T3	0%	101,247
glyburide 1.25 MG Oral Tablet glyburide	1,199	23.7%	T3	19.2%	59,131
glyburide 2.5 MG Oral Tablet glyburide	1,199	23.7%	T3	19.2%	59,131
glyburide 5 MG Oral Tablet glyburide	1,199	23.7%	T3	19.2%	59,131
{56 (tolvaptan 15 MG Oral Tablet [Jynarque]) } Pack [Jynarque 15/15 Carton] tolvaptan	1,197	23.6%	T5	91.7%	486
{28 (tolvaptan 15 MG Oral Tablet [Jynarque]) / 28 (tolvaptan 30 MG Oral Tablet [Jynarque]) } Pack [Jynarque 30/15 Carton] tolvaptan	1,197	23.6%	T5	91.7%	486
{28 (tolvaptan 15 MG Oral Tablet [Jynarque]) / 28 (tolvaptan 45 MG Oral Tablet [Jynarque]) } Pack [Jynarque 45/15 Carton] tolvaptan	1,197	23.6%	T5	91.7%	486
{28 (tolvaptan 30 MG Oral Tablet [Jynarque]) / 28 (tolvaptan 60 MG Oral Tablet [Jynarque]) } Pack [Jynarque 60/30 Carton] tolvaptan	1,197	23.6%	T5	91.7%	486
{28 (tolvaptan 30 MG Oral Tablet [Jynarque]) / 28 (tolvaptan 90 MG Oral Tablet [Jynarque]) } Pack [Jynarque 90/30 Carton] tolvaptan	1,197	23.6%	T5	91.7%	486
24 HR nisoldipine 20 MG Extended Release Oral Tablet nisoldipine	1,187	23.4%	T3	0%	-
24 HR nisoldipine 30 MG Extended Release Oral Tablet nisoldipine	1,187	23.4%	T3	0%	-
24 HR nisoldipine 40 MG Extended Release Oral Tablet nisoldipine	1,187	23.4%	T3	0%	-
metronidazole 375 MG Oral Capsule metronidazole	1,184	23.4%	T2	0%	1,528,785
fluocinonide 1 MG/ML Topical Cream fluocinonide	1,178	23.2%	T2	0%	379,768
0.4 ML methylnaltrexone bromide 20 MG/ML Prefilled Syringe [Relistor] methylnaltrexone bromide	1,177	23.2%	T4	66.9%	-
emtricitabine 200 MG / rilpivirine 25 MG / tenofovir disoproxil fumarate 300 MG Oral Tablet [Complera] emtricitabine	1,174	23.2%	T5	0%	997
200 ML immunoglobulin G, human 50 MG/ML Injection [Gammaplex] immunoglobulin G, human	1,173	23.1%	T4	98.1%	40
BX Rating 24 HR methylphenidate hydrochloride 18 MG Extended Release Oral Tablet BX Rating	1,167	23%	T3	3.6%	-
fluorouracil 5 MG/ML Topical Cream fluorouracil	1,166	23%	T4	9.8%	500,442
codeine sulfate 15 MG Oral Tablet codeine sulfate	1,162	22.9%	T3	0%	3,569
hydrocodone bitartrate 5 MG / ibuprofen 200 MG Oral Tablet hydrocodone bitartrate	1,151	22.7%	T3	0%	5,184
vonoprazan 10 MG Oral Tablet [Voquezna] vonoprazan	1,150	22.7%	T3	93.4%	48
vonoprazan 20 MG Oral Tablet [Voquezna] vonoprazan	1,150	22.7%	T3	93.4%	48
tizanidine 2 MG Oral Capsule tizanidine	1,144	22.6%	T2	0%	1,905,964
tizanidine 4 MG Oral Capsule tizanidine	1,144	22.6%	T2	0%	1,905,964
tizanidine 6 MG Oral Capsule tizanidine	1,141	22.5%	T2	0%	1,905,964
nifurtimox 30 MG Oral Tablet [Lampit] nifurtimox	1,135	22.4%	T4	5.4%	-
nifurtimox 120 MG Oral Tablet [Lampit] nifurtimox	1,135	22.4%	T4	5.4%	-
pretomanid 200 MG Oral Tablet pretomanid	1,134	22.4%	T4	33.3%	18
hydrocodone bitartrate 10 MG / ibuprofen 200 MG Oral Tablet hydrocodone bitartrate	1,130	22.3%	T3	0%	5,184
phenytoin 25 MG/ML Oral Suspension [Dilantin] phenytoin	1,129	22.3%	T4	4.2%	14,557
chenodeoxycholate 250 MG Oral Tablet [Chenodal] chenodeoxycholate	1,129	22.3%	T5	91.7%	38
ospemifene 60 MG Oral Tablet [Osphena] ospemifene	1,127	22.2%	T3	77.6%	4,511
84 HR estradiol 0.00208 MG/HR / norethindrone acetate 0.00583 MG/HR Transdermal System [Combipatch] estradiol	1,122	22.1%	T4	0%	3,033
84 HR estradiol 0.00208 MG/HR / norethindrone acetate 0.0104 MG/HR Transdermal System [Combipatch] estradiol	1,122	22.1%	T4	0%	3,033
mesalamine 250 MG Extended Release Oral Capsule [Pentasa] mesalamine	1,119	22.1%	T3	0%	95,185
60 ACTUAT testosterone 30 MG/ACTUAT Topical Solution	1,112	21.9%	T2	86.1%	-
28 ACTUAT teriparatide 0.02 MG/ACTUAT Pen Injector [Forteo]	1,109	21.9%	T5	94.1%	15,602
dextroamphetamine sulfate 5 MG Oral Tablet [Zenzedi] dextroamphetamine sulfate	1,106	21.8%	T3	0%	9,950
dextroamphetamine sulfate 10 MG Oral Tablet [Zenzedi] dextroamphetamine sulfate	1,106	21.8%	T3	0%	9,950
buprenorphine 11.4 MG / naloxone 2.9 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
buprenorphine 0.7 MG / naloxone 0.18 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
buprenorphine 1.4 MG / naloxone 0.36 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
buprenorphine 2.9 MG / naloxone 0.71 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
buprenorphine 5.7 MG / naloxone 1.4 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
buprenorphine 8.6 MG / naloxone 2.1 MG Sublingual Tablet [Zubsolv] buprenorphine	1,103	21.8%	T3	0%	74,893
24 HR carvedilol phosphate 10 MG Extended Release Oral Capsule carvedilol phosphate	1,099	21.7%	T3	0%	-
24 HR carvedilol phosphate 20 MG Extended Release Oral Capsule carvedilol phosphate	1,099	21.7%	T3	0%	-
24 HR carvedilol phosphate 40 MG Extended Release Oral Capsule carvedilol phosphate	1,099	21.7%	T3	0%	-
24 HR carvedilol phosphate 80 MG Extended Release Oral Capsule carvedilol phosphate	1,099	21.7%	T3	0%	-
ethacrynic acid 25 MG Oral Tablet ethacrynic acid	1,093	21.6%	T4	5.9%	3,813
cholic acid 50 MG Oral Capsule [Cholbam] cholic acid	1,092	21.6%	T5	100%	-
cholic acid 250 MG Oral Capsule [Cholbam] cholic acid	1,092	21.6%	T5	100%	-
50 ML immunoglobulin G, human 100 MG/ML Injection [Gammaplex] immunoglobulin G, human	1,085	21.4%	T4	100%	40
temazepam 22.5 MG Oral Capsule temazepam	1,084	21.4%	T2	24.1%	394,771
magnesium chloride 0.00148 MEQ/ML / potassium chloride 0.00497 MEQ/ML / sodium acetate 0.027 MEQ/ML / sodium chloride 0.0899 MEQ/ML / sodium gluconate 5.02 MG/ML Injectable Solution [Plasmalyte A] magnesium chloride	1,083	21.4%	T3	8.6%	-
diroximel fumarate 231 MG Delayed Release Oral Capsule [Vumerity] diroximel fumarate	1,081	21.3%	T4	96.6%	2,304
amoxicillin 250 MG / omeprazole 10 MG / rifabutin 12.5 MG Delayed Release Oral Capsule [Talicia] amoxicillin	1,080	21.3%	T4	0%	6,202,496
200 ML immunoglobulin G, human 100 MG/ML Injection [Gammaplex] immunoglobulin G, human	1,068	21.1%	T4	100%	40
glyburide 1.25 MG / metformin hydrochloride 250 MG Oral Tablet glyburide	1,066	21%	T3	19.6%	59,131
glyburide 2.5 MG / metformin hydrochloride 500 MG Oral Tablet glyburide	1,066	21%	T3	19.6%	59,131
glyburide 5 MG / metformin hydrochloride 500 MG Oral Tablet glyburide	1,066	21%	T3	19.6%	59,131
100 ML immunoglobulin G, human 100 MG/ML Injection [Gammaplex] immunoglobulin G, human	1,064	21%	T4	100%	40
1 ML abatacept 125 MG/ML Prefilled Syringe [Orencia] abatacept	1,060	20.9%	T4	98.8%	1,749
1 ML abatacept 125 MG/ML Auto-Injector [Orencia] abatacept	1,060	20.9%	T4	98.8%	1,749
0.4 ML abatacept 125 MG/ML Prefilled Syringe [Orencia] abatacept	1,060	20.9%	T4	98.8%	1,749
0.7 ML abatacept 125 MG/ML Prefilled Syringe [Orencia] abatacept	1,060	20.9%	T4	98.8%	1,749
30/70 Release 24 HR methylphenidate hydrochloride 10 MG Extended Release Oral Capsule	1,060	20.9%	T3	10.3%	-
168 HR estradiol 0.00188 MG/HR / levonorgestrel 0.000625 MG/HR Transdermal System [Climara Pro] estradiol	1,058	20.9%	T4	8.1%	1,983
0.2 ML adalimumab-ryvk 100 MG/ML Prefilled Syringe [Simlandi] adalimumab-ryvk	1,052	20.8%	T4	97.9%	-
0.4 ML adalimumab-ryvk 100 MG/ML Auto-Injector [Simlandi] adalimumab-ryvk	1,052	20.8%	T4	97.9%	-
0.4 ML adalimumab-ryvk 100 MG/ML Prefilled Syringe [Simlandi] adalimumab-ryvk	1,052	20.8%	T4	97.9%	-
24 HR timolol 5 MG/ML Ophthalmic Solution timolol	1,050	20.7%	T3	0%	-
30/70 Release 24 HR methylphenidate hydrochloride 20 MG Extended Release Oral Capsule	1,050	20.7%	T3	10.7%	-
30/70 Release 24 HR methylphenidate hydrochloride 40 MG Extended Release Oral Capsule	1,050	20.7%	T3	10.7%	-
acetaminophen 300 MG / hydrocodone bitartrate 5 MG Oral Tablet acetaminophen	1,048	20.7%	T3	0%	156
0.8 ML adalimumab-ryvk 100 MG/ML Auto-Injector [Simlandi] adalimumab-ryvk	1,048	20.7%	T4	97.9%	-
mavorixafor 100 MG Oral Capsule [Xolremdi] mavorixafor	1,046	20.6%	T4	100%	-
30/70 Release 24 HR methylphenidate hydrochloride 60 MG Extended Release Oral Capsule	1,046	20.6%	T3	10.9%	-
168 HR granisetron 0.129 MG/HR Transdermal System [Sancuso] granisetron	1,045	20.6%	T4	0%	1,178
calcitriol 0.000003 MG/MG Topical Ointment calcitriol	1,044	20.6%	T3	10%	310,587
promethazine hydrochloride 50 MG Rectal Suppository [Promethegan] promethazine hydrochloride	1,041	20.5%	T3	46.3%	523,738
pyridostigmine bromide 30 MG Oral Tablet pyridostigmine bromide	1,041	20.5%	T3	0%	56,300
dexamethasone 0.5 MG/ML / tobramycin 3 MG/ML Ophthalmic Suspension [Tobradex] dexamethasone	1,033	20.4%	T3	0%	850,184

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team