1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq]

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pegvaliase-pqpz

RxCUI: 2046380

Important: Drug coverage and costs vary by plan and location. Verify coverage directly with your Medicare plan before filling a prescription. This is informational data only and should not replace advice from your healthcare provider or pharmacist.
3.9%
Plan Coverage
198
Plans Covering
T4.1
Avg Tier
95.5%
Prior Auth Required

What the CMS Formulary Data Shows for 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq]

Per the CMS 2026 Part D formulary file, 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] (RxNorm concept RXCUI 2046380, generic name pegvaliase-pqpz) appears on 22 distinct formulary files spanning 198 Medicare Part D plan offerings - 3.9% of enrollable Part D products, selective placement; verify formulary inclusion before enrolling. Tier placement ranges from Tier 1 to Tier 5, with a cross-plan average of Tier 4.1.

Real-world access to 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] depends on utilization management as much as tier placement: 95.5% of covering formularies require prior authorization. 0% require step therapy. 18.2% apply quantity limits.

Historical spending context from the CMS Medicare Part D Drug Spending Dashboard shows 91 Part D beneficiaries filled 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] in 2023, with total plan-and-beneficiary spending of $20,307,239 and an average per-beneficiary annual cost of $223,156.47. The plan-by-plan detail below lists exactly which PDP and MA-PD contracts carry 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] today.

Coverage Details

Formularies covering
22
Plans covering
198
Coverage rate
3.9%
Tier range
Tier 1 – Tier 5
Average tier
Tier 4, Non-Preferred

Restrictions

Prior authorization required
95.5% of formularies
Step therapy required
0% of formularies
Quantity limits
18.2% of formularies

2023 Medicare Spending

Beneficiaries
91
Total spending
$20,307,239
Avg per beneficiary
$223,156.47

Tier Distribution Across Plans

6 plans
Tier 1, Preferred Generic
1 plans
Tier 2, Generic
3 plans
Tier 4, Non-Preferred
90 plans
Tier 5, Specialty

Medicare Advantage Plans (MA-PD) Covering 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq]

100 Medicare Advantage plans with Part D drug coverage include this drug.

Plan Insurer Tier PA Premium States
Hamaspik Medicare Choice (HMO D-SNP) HAMASPIK, INC. T1 Yes $0 NY
Mass General Brigham SCO (HMO D-SNP) MASS GENERAL BRIGHAM HEALTH PLAN, INC T1 Yes $0 MA
Mass General Brigham One Care (HMO D-SNP) MASS GENERAL BRIGHAM HEALTH PLAN, INC T1 Yes $0 MA
Gold Dialysis & Kidney Complete (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T1 Yes $4.80 FL
Gold Dialysis & Kidney Complete (HMO-POS C-SNP) GOLD KIDNEY OF ARIZONA T1 Yes $17.00 AZ
Hamaspik Medicare Select (HMO D-SNP) HAMASPIK, INC. T1 Yes $34.50 NY
CalOptima Health OneCare Complete (HMO D-SNP) ORANGE COUNTY HEALTH AUTHORITY T2 Yes $0 CA
PHP (HMO C-SNP) AIDS HEALTHCARE FOUNDATION T4 Yes $0 CA
VNS Health Total (HMO D-SNP) VNS CHOICE T4 Yes $0 NY
VNS Health EasyCare Plus (HMO D-SNP) VNS CHOICE T4 Yes $51.60 NY
Select Health Medicare Essential (HMO) SELECTHEALTH, INC. T5 Yes $0 UT
Select Health Medicare Essential (HMO) SELECTHEALTH, INC. T5 Yes $0 NV
Select Health Medicare Dual (HMO D-SNP) SELECTHEALTH, INC. T5 Yes $0 UT
Select Health Medicare Essential (HMO) SELECTHEALTH, INC. T5 Yes $0 UT
Select Health Medicare + Kroger (HMO) SELECTHEALTH, INC. T5 Yes $0 NV
Select Health Medicare + Kroger (HMO) SELECTHEALTH, INC. T5 Yes $0 UT
Select Health Medicare Essential (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare Essential (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare + Kroger (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare Flex (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare + Kroger (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare Active (HMO) SELECTHEALTH, INC. T5 Yes $0 CO
Select Health Medicare Dual (HMO D-SNP) SELECTHEALTH, INC. T5 Yes $0 NV
Select Health Medicare Wellness (HMO) SELECTHEALTH, INC. T5 Yes $0 NV
SummaCare Medicare Topaz (HMO) SUMMACARE INC. T5 Yes $0 OH
SummaCare Medicare Quartz (HMO) SUMMACARE INC. T5 Yes $0 OH
Healthy Mississippi Premier Advantage (HMO-POS) Healthy Mississippi, Inc. T5 Yes $0 MS
Gold Heart & Diabetes (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T5 Yes $0 FL
Gold Heart & Diabetes Complete (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T5 Yes $0 FL
Gold Dialysis & Kidney (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T5 Yes $0 FL
Gold Health (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T5 Yes $0 FL
Gold Dialysis & Kidney (HMO-POS C-SNP) GOLD KIDNEY OF FLORIDA INC T5 Yes $0 FL
Gold Heart & Diabetes (HMO-POS C-SNP) GOLD KIDNEY OF ARIZONA T5 Yes $0 AZ
Gold Dialysis & Kidney (HMO-POS C-SNP) GOLD KIDNEY OF ARIZONA T5 Yes $0 AZ
Gold Heart & Diabetes (HMO-POS C-SNP) GOLD KIDNEY OF ARIZONA T5 Yes $0 AZ
Gold Dialysis & Kidney (HMO-POS C-SNP) GOLD KIDNEY OF ARIZONA T5 Yes $0 AZ
VillageCareMAX Medicare Health Advantage Plan (HMO D-SNP) VILLAGE SENIOR SERVICES CORPORATION T5 Yes $0 NY
VillageCareMAX Medicare Total Advantage Plan (HMO D-SNP) VILLAGE SENIOR SERVICES CORPORATION T5 Yes $0 NY
Kaiser Permanente Senior Advantage LA, Orange Co. (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Enhanced Solano (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Inland Empire (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Sr Adv Enhanced Marin San Mateo (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Ventura (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Enhanced Kern (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Basic Kern (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage San Diego (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Sr Adv Enhanced Santa Clara (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Enhanced Stanis (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Basic Stanis (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA
Kaiser Permanente Senior Advantage Basic SnJoaq (HMO) KAISER FOUNDATION HP, INC. T5 No $0 CA

Frequently Asked Questions

Is 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] covered by Medicare Part D?

Yes, 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] is covered by 198 Medicare Part D plans (3.9% of all Part D formularies).

What tier is 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] on Medicare Part D plans?

1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] averages Tier 4.1 across Part D plans, ranging from Tier 1 to Tier 5.

Does 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] require prior authorization?

95.5% of Part D formularies require prior authorization for 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq]. Step therapy: 0%. Quantity limits: 18.2%.

How much does Medicare spend on 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq]?

In 2023, total Medicare Part D spending on 1 ML pegvaliase-pqpz 20 MG/ML Prefilled Syringe [Palynziq] was $20,307,239, covering 91 beneficiaries. The average spend per beneficiary was $223,156.47.

Data sourced from the Centers for Medicare & Medicaid Services (CMS). See our methodology for details. Retrieved and formatted by PlainMedicare Editorial