Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.
Drug Name Plans Covering Coverage % Avg Tier PA % 2023 Benes
24 HR paliperidone 9 MG Extended Release Oral Tablet [Invega]
paliperidone
2 0% T1 100% 2,964
abacavir 20 MG/ML Oral Solution [Ziagen]
abacavir
2 0% T1 0% 2,809
etravirine 100 MG Oral Tablet [Intelence]
etravirine
2 0% T1 0% 2,742
etravirine 200 MG Oral Tablet [Intelence]
etravirine
2 0% T1 0% 2,742
alosetron 0.5 MG Oral Tablet [Lotronex]
alosetron
2 0% T1 100% 2,223
alosetron 1 MG Oral Tablet [Lotronex]
alosetron
2 0% T1 100% 2,223
24 HR quetiapine 50 MG Extended Release Oral Tablet [Seroquel]
quetiapine
2 0% T1 100% 1,943
24 HR quetiapine 150 MG Extended Release Oral Tablet [Seroquel]
quetiapine
2 0% T1 100% 1,943
24 HR quetiapine 200 MG Extended Release Oral Tablet [Seroquel]
quetiapine
2 0% T1 100% 1,943
24 HR quetiapine 300 MG Extended Release Oral Tablet [Seroquel]
quetiapine
2 0% T1 100% 1,943
24 HR quetiapine 400 MG Extended Release Oral Tablet [Seroquel]
quetiapine
2 0% T1 100% 1,943
atazanavir 300 MG Oral Capsule [Reyataz]
atazanavir
2 0% T1 0% 1,861
atazanavir 200 MG Oral Capsule [Reyataz]
atazanavir
2 0% T1 0% 1,861
ciprofloxacin 500 MG Oral Tablet [Cipro]
ciprofloxacin
2 0% T1 0% 1,810
ciprofloxacin 250 MG Oral Tablet [Cipro]
ciprofloxacin
2 0% T1 0% 1,810
tranylcypromine 10 MG Oral Tablet [Parnate]
tranylcypromine
2 0% T1 0% 1,773
24 HR mesalamine 375 MG Extended Release Oral Capsule [Apriso]
mesalamine
2 0% T1 0% 1,717
24 HR desvenlafaxine succinate 25 MG Extended Release Oral Tablet [Pristiq]
desvenlafaxine succinate
2 0% T1 0% 1,555
24 HR desvenlafaxine succinate 50 MG Extended Release Oral Tablet [Pristiq]
desvenlafaxine succinate
2 0% T1 0% 1,555
24 HR desvenlafaxine succinate 100 MG Extended Release Oral Tablet [Pristiq]
desvenlafaxine succinate
2 0% T1 0% 1,555
aztreonam 1000 MG Injection [Azactam]
aztreonam
2 0% T1 0% 1,454
aztreonam 2000 MG Injection [Azactam]
aztreonam
2 0% T1 0% 1,454
sunitinib 12.5 MG Oral Capsule [Sutent]
sunitinib
2 0% T1 100% 1,343
sunitinib 25 MG Oral Capsule [Sutent]
sunitinib
2 0% T1 100% 1,343
sunitinib 37.5 MG Oral Capsule [Sutent]
sunitinib
2 0% T1 100% 1,343
sunitinib 50 MG Oral Capsule [Sutent]
sunitinib
2 0% T1 100% 1,343
malathion 5 MG/ML Topical Lotion [Ovide]
malathion
2 0% T1 0% 1,252
250 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
estradiol
2 0% T1 0% 1,057
500 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
estradiol
2 0% T1 0% 1,057
1000 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
estradiol
2 0% T1 0% 1,057
750 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
estradiol
2 0% T1 0% 1,057
1250 MG estradiol 0.001 MG/MG Topical Gel [Divigel]
estradiol
2 0% T1 0% 1,057
emtricitabine 200 MG Oral Capsule [Emtriva]
emtricitabine
2 0% T1 0% 997
Pulmonary Hypertension tadalafil 20 MG Oral Tablet [Adcirca]
Pulmonary Hypertension tadalafil
2 0% T1 100% 802
lopinavir 100 MG / ritonavir 25 MG Oral Tablet [Kaletra]
lopinavir
2 0% T1 0% 749
lopinavir 200 MG / ritonavir 50 MG Oral Tablet [Kaletra]
lopinavir
2 0% T1 0% 749
tigecycline 50 MG Injection [Tygacil]
tigecycline
2 0% T1 0% 655
{21 (methylprednisolone 4 MG Oral Tablet [Medrol]) } Pack [Medrol Dosepak]
methylprednisolone
2 0% T1 0% 588
diazoxide 50 MG/ML Oral Suspension [Proglycem]
diazoxide
2 0% T1 0% 525
ascorbic acid 4700 MG / polyethylene glycol 3350 100000 MG / potassium chloride 1015 MG / sodium ascorbate 5900 MG / sodium chloride 2690 MG / sodium sulfate 7500 MG Powder for Oral Solution [MoviPrep]
ascorbic acid
2 0% T1 0% 517
tasimelteon 20 MG Oral Capsule [Hetlioz]
tasimelteon
2 0% T1 100% 499
benzoyl peroxide 0.05 MG/MG / erythromycin 0.03 MG/MG Topical Gel [Benzamycin]
benzoyl peroxide
2 0% T1 0% 465
alendronic acid 70 MG Oral Tablet [Fosamax]
alendronic acid
2 0% T1 0% 424
24 HR timolol 5 MG/ML Ophthalmic Solution [Istalol]
timolol
2 0% T1 0% 410
0.4 ML enoxaparin sodium 100 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
0.6 ML enoxaparin sodium 100 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
0.8 ML enoxaparin sodium 100 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
1 ML enoxaparin sodium 100 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
0.3 ML enoxaparin sodium 100 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
0.8 ML enoxaparin sodium 150 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
1 ML enoxaparin sodium 150 MG/ML Prefilled Syringe [Lovenox]
enoxaparin sodium
2 0% T1 0% 339
lapatinib 250 MG Oral Tablet [Tykerb]
lapatinib
2 0% T1 100% 260
Hyponatremia tolvaptan 15 MG Oral Tablet [Samsca]
Hyponatremia tolvaptan
2 0% T1 100% 165
Hyponatremia tolvaptan 30 MG Oral Tablet [Samsca]
Hyponatremia tolvaptan
2 0% T1 100% 165
penicillamine 250 MG Oral Tablet [Depen]
penicillamine
2 0% T1 0% 162
sapropterin dihydrochloride 100 MG Oral Tablet [Kuvan]
sapropterin dihydrochloride
2 0% T1 100% 137
sapropterin dihydrochloride 100 MG Powder for Oral Solution [Kuvan]
sapropterin dihydrochloride
2 0% T1 100% 137
sapropterin dihydrochloride 500 MG Powder for Oral Solution [Kuvan]
sapropterin dihydrochloride
2 0% T1 100% 137
vigabatrin 500 MG Oral Tablet [Sabril]
vigabatrin
2 0% T1 0% 124
vigabatrin 500 MG Powder for Oral Solution [Sabril]
vigabatrin
2 0% T1 0% 124
{4 (risedronate sodium 35 MG Delayed Release Oral Tablet) } Pack [Atelvia]
risedronate sodium
2 0% T1 0% 117
24 HR diltiazem hydrochloride 120 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
24 HR diltiazem hydrochloride 180 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
24 HR diltiazem hydrochloride 240 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
24 HR diltiazem hydrochloride 300 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
24 HR diltiazem hydrochloride 360 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
24 HR diltiazem hydrochloride 420 MG Extended Release Oral Capsule [Tiazac]
diltiazem hydrochloride
2 0% T1 0% 114
0.5 ML sumatriptan 12 MG/ML Cartridge [Imitrex]
sumatriptan
2 0% T1 0% 99
0.5 ML sumatriptan 8 MG/ML Cartridge [Imitrex]
sumatriptan
2 0% T1 0% 99
pyrimethamine 25 MG Oral Tablet [Daraprim]
pyrimethamine
2 0% T1 100% 95
sodium phenylbutyrate 500 MG Oral Tablet [Buphenyl]
sodium phenylbutyrate
2 0% T1 100% 69
24 HR diltiazem hydrochloride 120 MG Extended Release Oral Capsule [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 180 MG Extended Release Oral Capsule [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 240 MG Extended Release Oral Capsule [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 300 MG Extended Release Oral Capsule [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 360 MG Extended Release Oral Capsule [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 120 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 180 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 240 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 300 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 360 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR diltiazem hydrochloride 420 MG Extended Release Oral Tablet [Cardizem]
diltiazem hydrochloride
2 0% T1 0% 44
24 HR nisoldipine 8.5 MG Extended Release Oral Tablet [Sular]
nisoldipine
2 0% T1 0% 35
24 HR nisoldipine 17 MG Extended Release Oral Tablet [Sular]
nisoldipine
2 0% T1 0% 35
24 HR nisoldipine 34 MG Extended Release Oral Tablet [Sular]
nisoldipine
2 0% T1 0% 35
tolcapone 100 MG Oral Tablet [Tasmar]
tolcapone
2 0% T1 0% 25
{1 (aprepitant 125 MG Oral Capsule [Emend]) / 2 (aprepitant 80 MG Oral Capsule [Emend]) } Pack [Emend Tri-Fold Pack]
aprepitant
2 0% T1 100% 22
metyrosine 250 MG Oral Capsule [Demser]
metyrosine
2 0% T1 0% 20
pentamidine isethionate 300 MG Injection [Pentam]
pentamidine isethionate
2 0% T1 0% 20
Augmented betamethasone 0.0005 MG/MG Topical Ointment [Diprolene]
Augmented betamethasone
2 0% T1 0% 17
{24 (drospirenone 3 MG / estetrol 14.2 MG Oral Tablet) / 4 (inert ingredients 1 MG Oral Tablet) } Pack [Nextstellis 28 Day]
drospirenone
2 0% T2 0% -
24 HR venlafaxine 150 MG Extended Release Oral Capsule [Effexor]
venlafaxine
2 0% T1 0% -
24 HR glipizide 5 MG Extended Release Oral Tablet [Glucotrol]
glipizide
2 0% T1 0% -
Osmotic 24 HR nifedipine 30 MG Extended Release Oral Tablet [Procardia]
Osmotic
2 0% T1 0% -
Osmotic 24 HR nifedipine 60 MG Extended Release Oral Tablet [Procardia]
Osmotic
2 0% T1 0% -
Osmotic 24 HR nifedipine 90 MG Extended Release Oral Tablet [Procardia]
Osmotic
2 0% T1 0% -
{6 (azithromycin 250 MG Oral Tablet [Zithromax]) } Pack [Z-PAK]
azithromycin
2 0% T1 0% -
{3 (azithromycin 500 MG Oral Tablet [Zithromax]) } Pack [TRI-PAK]
azithromycin
2 0% T1 0% -
12 HR bupropion hydrochloride 150 MG Extended Release Oral Tablet [Wellbutrin]
bupropion hydrochloride
2 0% T1 0% -
12 HR bupropion hydrochloride 200 MG Extended Release Oral Tablet [Wellbutrin]
bupropion hydrochloride
2 0% T1 0% -
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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.