Medicare Part D Drug Coverage List

According to the Centers for Medicare & Medicaid Services (CMS) 2026 Part D formulary data, this list covers 6,046 drugs across Medicare Part D plans, sorted by how broadly each is covered. Under the Inflation Reduction Act, Part D out-of-pocket costs are capped at $2,000 a year in 2026; see our methodology for how coverage breadth is calculated.

Coverage varies by plan and geography. Verify drug coverage with your specific plan before making decisions.

Overview Browse Drugs Part D Plans Rankings

Drug Name	Plans Covering	Coverage %	Avg Tier	PA %	2023 Benes
pantoprazole 40 MG Oral Granules pantoprazole	33	0.7%	T2	0%	6,191,845
doxycycline hyclate 150 MG Oral Tablet doxycycline hyclate	33	0.7%	T2	0%	4,121,486
tadalafil 4 MG/ML Oral Suspension [Tadliq] tadalafil	33	0.7%	T4	100%	74,638
Sensor 3 ML insulin glargine 100 UNT/ML Pen Injector [Basaglar] Sensor	33	0.7%	T4	25%	-
0.5 ML testosterone enanthate 200 MG/ML Auto-Injector [Xyosted] testosterone enanthate	32	0.6%	T3	100%	5,120
0.5 ML testosterone enanthate 100 MG/ML Auto-Injector [Xyosted] testosterone enanthate	32	0.6%	T3	100%	5,120
0.5 ML testosterone enanthate 150 MG/ML Auto-Injector [Xyosted] testosterone enanthate	32	0.6%	T3	100%	5,120
bismuth subcitrate 140 MG / metronidazole 125 MG / tetracycline hydrochloride 125 MG Oral Capsule [Pylera] bismuth subcitrate	32	0.6%	T3	20%	-
0.8 ML donidalorsen 100 MG/ML Auto-Injector [Dawnzera] donidalorsen	32	0.6%	T4	100%	-
levothyroxine sodium 0.013 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.025 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.0375 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.044 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.05 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.0625 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.075 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.088 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.1 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.112 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.125 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.137 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.15 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.175 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
levothyroxine sodium 0.2 MG Oral Capsule [Tirosint] levothyroxine sodium	31	0.6%	T3	0%	8,687,969
desonide 0.0005 MG/MG Topical Gel desonide	31	0.6%	T4	0%	101,247
dasatinib 70 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
dasatinib 20 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
dasatinib 50 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
dasatinib 100 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
dasatinib 80 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
dasatinib 140 MG Oral Tablet [Sprycel] dasatinib	31	0.6%	T4	100%	5,120
1 ML tildrakizumab-asmn 100 MG/ML Prefilled Syringe [Ilumya] tildrakizumab-asmn	31	0.6%	T4	100%	629
24 HR dapagliflozin 5 MG / metformin hydrochloride 1000 MG Extended Release Oral Tablet dapagliflozin	31	0.6%	T3	0%	-
24 HR dapagliflozin 10 MG / metformin hydrochloride 1000 MG Extended Release Oral Tablet dapagliflozin	31	0.6%	T3	0%	-
3 ML apomorphine hydrochloride 10 MG/ML Cartridge [Apokyn] apomorphine hydrochloride	30	0.6%	T4	25%	581
{28 (drospirenone 0.25 MG / estradiol 0.5 MG Oral Tablet) } Pack [Angeliq 0.25/0.5 28 Day] drospirenone	30	0.6%	T4	0%	-
metformin hydrochloride 500 MG / sitagliptin 50 MG Oral Tablet metformin hydrochloride	29	0.6%	T2	0%	5,918,026
metformin hydrochloride 1000 MG / sitagliptin 50 MG Oral Tablet metformin hydrochloride	29	0.6%	T2	0%	5,918,026
tramadol hydrochloride 25 MG Oral Tablet tramadol hydrochloride	29	0.6%	T2	8.3%	3,884,717
spironolactone 5 MG/ML Oral Suspension spironolactone	29	0.6%	T2	0%	2,081,937
hydrocortisone 25 MG/ML Topical Solution hydrocortisone	29	0.6%	T3	0%	1,257,661
vancomycin 25 MG/ML Oral Solution [Firvanq] vancomycin	29	0.6%	T3	0%	161,077
vancomycin 50 MG/ML Oral Solution [Firvanq] vancomycin	29	0.6%	T3	0%	161,077
metaxalone 400 MG Oral Tablet metaxalone	29	0.6%	T3	50%	24,167
amphetamine sulfate 10 MG Oral Tablet amphetamine sulfate	29	0.6%	T4	100%	203
amphetamine sulfate 5 MG Oral Tablet amphetamine sulfate	29	0.6%	T4	100%	203
hydrocortisone 20 MG/ML Topical Lotion [Ala-Scalp] hydrocortisone	28	0.6%	T2	0%	1,257,661
amylase 24600 UNT / lipase 4200 UNT / protease 14200 UNT Delayed Release Oral Capsule [Pancreaze] amylase	28	0.6%	T3	16.7%	2,095
amylase 61500 UNT / lipase 10500 UNT / protease 35500 UNT Delayed Release Oral Capsule [Pancreaze] amylase	28	0.6%	T3	16.7%	2,095
amylase 98400 UNT / lipase 16800 UNT / protease 56800 UNT Delayed Release Oral Capsule [Pancreaze] amylase	28	0.6%	T3	16.7%	2,095
amylase 83900 UNT / lipase 21000 UNT / protease 54700 UNT Delayed Release Oral Capsule [Pancreaze] amylase	28	0.6%	T4	16.7%	2,095
lofexidine 0.18 MG Oral Tablet [Lucemyra] lofexidine	28	0.6%	T4	0%	781
asenapine 2.5 MG Sublingual Tablet [Saphris] asenapine	28	0.6%	T3	50%	714
24 HR tramadol hydrochloride 100 MG Extended Release Oral Capsule tramadol hydrochloride	28	0.6%	T2	50%	-
24 HR tramadol hydrochloride 200 MG Extended Release Oral Capsule tramadol hydrochloride	28	0.6%	T2	50%	-
24 HR tramadol hydrochloride 300 MG Extended Release Oral Capsule tramadol hydrochloride	28	0.6%	T2	50%	-
methocarbamol 1000 MG Oral Tablet [Tanlor] methocarbamol	27	0.5%	T2	0%	1,036,252
esomeprazole 20 MG / naproxen 375 MG Delayed Release Oral Tablet esomeprazole	27	0.5%	T4	100%	685,529
esomeprazole 20 MG / naproxen 500 MG Delayed Release Oral Tablet esomeprazole	27	0.5%	T4	100%	685,529
benzoyl peroxide 0.0375 MG/MG / clindamycin phosphate 0.012 MG/MG Topical Gel benzoyl peroxide	27	0.5%	T3	0%	465
168 HR estradiol 0.000583 MG/HR Transdermal System [Menostar] estradiol	27	0.5%	T4	25%	404
1 ML medroxyprogesterone acetate 150 MG/ML Injection [Depo-Provera] medroxyprogesterone acetate	27	0.5%	T3	0%	61
1 ML medroxyprogesterone acetate 150 MG/ML Prefilled Syringe [Depo-Provera] medroxyprogesterone acetate	27	0.5%	T3	0%	61
levothyroxine sodium 0.025 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.05 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.075 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.088 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.1 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.125 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.15 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.175 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
levothyroxine sodium 0.2 MG Oral Capsule levothyroxine sodium	26	0.5%	T3	0%	8,687,969
hydralazine hydrochloride 37.5 MG / isosorbide dinitrate 20 MG Oral Tablet [Bidil] hydralazine hydrochloride	26	0.5%	T3	0%	1,411,222
fluocinolone acetonide 0.1 MG/ML Otic Solution [Dermotic] fluocinolone acetonide	26	0.5%	T3	0%	80,799
ketoprofen 25 MG Oral Capsule ketoprofen	26	0.5%	T2	0%	1,019
10 ML plazomicin 50 MG/ML Injection [Zemdri] plazomicin	26	0.5%	T5	0%	-
0.5 ML tirzepatide 30 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
0.5 ML tirzepatide 25 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
0.5 ML tirzepatide 20 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
0.5 ML tirzepatide 15 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
0.5 ML tirzepatide 10 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
0.5 ML tirzepatide 5 MG/ML Auto-Injector [Zepbound] tirzepatide	26	0.5%	T4	100%	-
24 HR metformin hydrochloride 500 MG / sitagliptin 50 MG Extended Release Oral Tablet metformin hydrochloride	25	0.5%	T2	0%	-
24 HR metformin hydrochloride 1000 MG / sitagliptin 50 MG Extended Release Oral Tablet metformin hydrochloride	25	0.5%	T2	0%	-
24 HR metformin hydrochloride 1000 MG / sitagliptin 100 MG Extended Release Oral Tablet metformin hydrochloride	25	0.5%	T2	0%	-
60 ACTUAT fluticasone propionate 0.1 MG/ACTUAT / salmeterol 0.05 MG/ACTUAT Dry Powder Inhaler [Advair]	25	0.5%	T3	0%	-
60 ACTUAT fluticasone propionate 0.25 MG/ACTUAT / salmeterol 0.05 MG/ACTUAT Dry Powder Inhaler [Advair]	25	0.5%	T3	0%	-
60 ACTUAT fluticasone propionate 0.5 MG/ACTUAT / salmeterol 0.05 MG/ACTUAT Dry Powder Inhaler [Advair]	25	0.5%	T3	0%	-
30 ACTUAT fluticasone furoate 0.1 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler	25	0.5%	T2	0%	-
30 ACTUAT fluticasone furoate 0.2 MG/ACTUAT / vilanterol 0.025 MG/ACTUAT Dry Powder Inhaler	25	0.5%	T2	0%	-
amylase 15200 UNT / lipase 2600 UNT / protease 8800 UNT Delayed Release Oral Capsule [Pancreaze] amylase	24	0.5%	T3	20%	2,095
amylase 149900 UNT / lipase 37000 UNT / protease 97300 UNT Delayed Release Oral Capsule [Pancreaze] amylase	24	0.5%	T3	20%	2,095
diclofenac potassium 50 MG Powder for Oral Solution diclofenac potassium	23	0.5%	T3	0%	147,980
ertugliflozin 5 MG Oral Tablet [Steglatro] ertugliflozin	23	0.5%	T4	33.3%	722
ertugliflozin 15 MG Oral Tablet [Steglatro] ertugliflozin	23	0.5%	T4	33.3%	722
ertugliflozin 2.5 MG / metformin hydrochloride 500 MG Oral Tablet [Segluromet] ertugliflozin	23	0.5%	T4	33.3%	722
ertugliflozin 7.5 MG / metformin hydrochloride 500 MG Oral Tablet [Segluromet] ertugliflozin	23	0.5%	T4	33.3%	722
ertugliflozin 2.5 MG / metformin hydrochloride 1000 MG Oral Tablet [Segluromet] ertugliflozin	23	0.5%	T4	33.3%	722
ertugliflozin 7.5 MG / metformin hydrochloride 1000 MG Oral Tablet [Segluromet] ertugliflozin	23	0.5%	T4	33.3%	722
vosoritide 0.4 MG Injection [Voxzogo] vosoritide	23	0.5%	T4	100%	-

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Source: CMS Quarterly Prescription Drug Plan Formulary PUF 2026. 6,046 drugs with RXCUI identifiers from NLM RxNorm. Coverage percentages based on 0 active Part D plans.

Compiled by Plainmedicare Editorial, Health Insurance Editorial Team