Medicare Part D coverage · piperacillin · RxCUI 1659134

piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn]

Per the CMS 2026 Part D formulary file, piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] is covered by 408 Medicare Part D plans (8.1% of enrollable products), averaging Tier 3.4, with prior authorization required on 0% of covering formularies.

8.1%
Plan coverage
408
Plans covering
T3.4
Avg tier
0%
Prior auth required

Verify with CMS →

Important: Drug coverage and costs vary by plan and location. Verify coverage directly with your Medicare plan before filling a prescription. This is informational data only and should not replace advice from your healthcare provider or pharmacist.

What the CMS Formulary Data Shows for piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn]

Per the CMS 2026 Part D formulary file, piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] (RxNorm concept RXCUI 1659134, generic name piperacillin) appears on 35 distinct formulary files spanning 408 Medicare Part D plan offerings - 8.1% of enrollable Part D products, selective placement; verify formulary inclusion before enrolling. Tier placement ranges from Tier 1 to Tier 4, with a cross-plan average of Tier 3.4.

Real-world access to piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] depends on utilization management as much as tier placement: 0% of covering formularies require prior authorization. 0% require step therapy. 0% apply quantity limits.

Historical spending context from the CMS Medicare Part D Drug Spending Dashboard shows 22,422 Part D beneficiaries filled piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] in 2023, with total plan-and-beneficiary spending of $14,109,478 and an average per-beneficiary annual cost of $629.27. The plan-by-plan detail below lists exactly which PDP and MA-PD contracts carry piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] today.

Coverage Details

Formularies covering
35
Plans covering
408
Coverage rate
8.1%
Tier range
Tier 1 – Tier 4
Average tier
Tier 3, Preferred Brand

Restrictions

Prior authorization required
0% of formularies
Step therapy required
0% of formularies
Quantity limits
0% of formularies

2023 Medicare Spending

Beneficiaries
22,422
Total spending
$14,109,478
Avg per beneficiary
$629.27

Tier Distribution Across Plans

18 plans
Tier 1, Preferred Generic
82 plans
Tier 4, Non-Preferred

Medicare Advantage Plans (MA-PD) Covering piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn]

100 Medicare Advantage plans with Part D drug coverage include this drug.

Plan Insurer Tier PA Premium States
Gold Coast Health Plan Total Care Advantage (HMO D-SNP) Ventura County Medi-Cal Managed Care Commission T1 No $0 CA
Blue Cross Medicare Advantage Dual Care Plus (HMO D-SNP) Health Care Service Corporation T1 No $0 NM
Blue Cross MA Dual Care Plus Preferred (PPO D-SNP) Health Care Service Corporation T1 No $0 NM
SecureBlue (HMO D-SNP) HMO Minnesota T1 No $0 MN
Hamaspik Medicare Choice (HMO D-SNP) Hamaspik, Inc. T1 No $0 NY
SeniorCare Complete (HMO D-SNP) South Country Health Alliance T1 No $0 MN
AbilityCare (HMO D-SNP) South Country Health Alliance T1 No $0 MN
Alameda Alliance Wellness (HMO D-SNP) Alameda Alliance FOR Health T1 No $0 CA
Highmark Wholecare Medicare Assured Diamond (HMO D-SNP) Gateway Health Plan, Inc. T1 No $0 PA
Highmark Wholecare Medicare Assured Diamond (HMO D-SNP) Gateway Health Plan, Inc. T1 No $0 PA
Highmark Health Options Duals (HMO D-SNP) Highmark Health Options West Virginia Inc. T1 No $0 WV
Highmark Health Options Duals (HMO D-SNP) Highmark Bcbsd, Inc. T1 No $0 DE
Blue Cross Medicare Advantage Dual Care Plus (HMO D-SNP) Hcsc Insurance Services Company T1 No $4.80 TX
Blue Cross Medicare Advantage Dual Care Plus (HMO D-SNP) GHS Insurance Company T1 No $5.00 OK
Highmark Wholecare Medicare Assured Ruby (HMO D-SNP) Gateway Health Plan, Inc. T1 No $13.10 PA
Highmark Wholecare Medicare Assured Ruby (HMO D-SNP) Gateway Health Plan, Inc. T1 No $17.60 PA
Highmark Health Options Duals Select (HMO D-SNP) Highmark Bcbsd, Inc. T1 No $31.20 DE
Hamaspik Medicare Select (HMO D-SNP) Hamaspik, Inc. T1 No $34.50 NY
Anthem I CareMore Medicare Advantage 2 (HMO-POS) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Chronic Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Show the next 30 plans
Anthem I CareMore Home Care (HMO I-SNP) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Chronic Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Lung Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Kidney Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Lung Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Anthem I CareMore Kidney Care (HMO-POS C-SNP) Blue Cross OF California T4 No $0 CA
Wellpoint Lung Care (HMO-POS C-SNP) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint Chronic Care (HMO-POS C-SNP) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint Medicare Advantage 1 (HMO-POS) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint Premium Savings (HMO) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint I CareMore Home Care (HMO I-SNP) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint I CareMore Home Care (HMO I-SNP) Wellpoint Health Plans, Inc. T4 No $0 AZ
Wellpoint Medicare Advantage 2 (HMO-POS) Wellpoint Texas, Inc. T4 No $0 AZ
Wellpoint I CareMore Home Care 2 (HMO I-SNP) Wellpoint Texas, Inc. T4 No $0 AZ
Wellpoint Lung Care 2 (HMO-POS C-SNP) Wellpoint Texas, Inc. T4 No $0 AZ
Wellpoint Chronic Care 2 (HMO-POS C-SNP) Wellpoint Texas, Inc. T4 No $0 AZ
Wellpoint I CareMore Kidney Care (HMO-POS C-SNP) Wellpoint Texas, Inc. T4 No $0 AZ
Anthem Chronic Care (HMO-POS C-SNP) Healthkeepers, Inc. T4 No $0 VA
Anthem I CareMore Medicare Advantage (HMO-POS) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Premium Savings (HMO-POS) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Medicare Advantage (HMO-POS) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Chronic Care 2 (HMO-POS C-SNP) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Chronic Care 2 (HMO-POS C-SNP) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Lung Care 2 (HMO-POS C-SNP) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Lung Care 2 (HMO-POS C-SNP) Blue Cross OF California Partnership Plan, Inc. T4 No $0 CA
Anthem I CareMore Medicare Advantage (HMO-POS) HMO Colorado, Inc. T4 No $0 NV
Anthem I CareMore Lung Care (HMO-POS C-SNP) HMO Colorado, Inc. T4 No $0 NV
Anthem I CareMore Chronic Care (HMO-POS C-SNP) HMO Colorado, Inc. T4 No $0 NV
Anthem I CareMore Home Care (HMO I-SNP) HMO Colorado, Inc. T4 No $0 NV
Anthem I CareMore Kidney Care (HMO-POS C-SNP) HMO Colorado, Inc. T4 No $0 NV

Showing top 50 of 100 plans.

Frequently Asked Questions

Is piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] covered by Medicare Part D?

Yes, piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] is covered by 408 Medicare Part D plans (8.1% of all Part D formularies).

What tier is piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] on Medicare Part D plans?

piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] averages Tier 3.4 across Part D plans, ranging from Tier 1 to Tier 4.

Does piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] require prior authorization?

0% of Part D formularies require prior authorization for piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn]. Step therapy: 0%. Quantity limits: 0%.

How much does Medicare spend on piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn]?

In 2023, total Medicare Part D spending on piperacillin 2000 MG / tazobactam 250 MG Injection [Zosyn] was $14,109,478, covering 22,422 beneficiaries. The average spend per beneficiary was $629.27.

Nationwide similar Part D drugs

Data-derived peers across the CMS Part D formulary extract: nearest average tier placement and nearest prior-authorization rate. Not therapeutic alternatives or same-generic strengths.

Data sourced from the Centers for Medicare & Medicaid Services (CMS). See our methodology for details. Retrieved and formatted by PlainMedicare